TREATMENTS &
RESEARCH

Search the
latest
treatment
information
here.

Dr. Huntley's
Diagnosis
Checklist

Have a symptom?
See what questions
a doctor would ask.
 
Diseases » Plague » Prevalence
 

Prevalence and Incidence of Plague

Plague: Rare Disease

Plague is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Plague, or a subtype of Plague, affects less than 200,000 people in the US population.

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Plague as a "rare disease". More information about Plague is available from Orphanet

Plague Prevalence: Book Excerpts

Incidence (annual) of Plague:

9 annual cases of plague notified in USA 1999 (MMWR 1999) ... see also overview of Plague.

Incidence Rate:

approx 1 in 30,222,221 or 0.00% or 9 people in USA [Source statistic for calcuation: "9 annual cases of plague notified in USA 1999 (MMWR 1999)" -- see also general information about data sources]

Incidence extrapolations for USA for Plague:

9 per year, 0 per month, 0 per week, 0 per day, 0 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "9 annual cases of plague notified in USA 1999 (MMWR 1999)" -- see also general information about data sources]

Prevalance of Plague:

In the U.S., 1 to 40 cases reported annually (avg = 13 cases) by western states, 1971-1995

  • Worldwide, 2861 cases reported by 10 countries to WHO in 1995

    SEQUELAE

    • Rare, consequences of disseminated intravascular coagulation, lung damage
    • Mortality 50-90% if untreated; 15% when diagnosed and treated

    COSTS

    • Not known

    TRANSMISSION

    • Flea-borne, from infected rodents to humans
    • Direct contact with infected tissues or fluids from handling sick or dead animals
    • Respiratory droplets from cats and humans with pneumonic plague

    RESERVOIRS

    • Primarily wild rodents in U.S. (especially rock squirrels, ground squirrels, prairie dogs, other burrowing rodents)
    • Commensal rats may be important elsewhere

    RISK GROUPS

    • In the U.S., persons exposed to rodent fleas, wild rodents, or other susceptible animals in enzootic areas of western states
    • Most cases occur in southwestern states of NM, AZ, CO, and in CA
    • Highest rates in Native Americans, especially Navajos; other risk groups: hunters; veterinarians and pet owners handling infected cats; campers or hikers entering areas with outbreaks of animal plague

    SURVEILLANCE

    • National Notifiable Disease Surveillance System (NNDSS) for animal plague surveillance, for reports of human cases, and laboratory testing of fleas, animal tissues and serum specimens, and serosurveys of carnivores
    • CDC, Fort Collins, is a WHO Collaborating Center for Reference and Research on Plague Control, and reports all human plague cases in the U.S. to WHO

    OPPORTUNITIES

    • Increased self-sufficiency of state and county public health labs
    • Expanded active surveillance through carnivore serosurveys and application of geographic information systems (GIS) to surveillance programs
    • Increased education of public and health professionals
    • Collaborative applied research on plague prevention and control with other federal, state, and local health agencies, including application of GIS to surveillance

    RESEARCH

    • Ecology-based prevention and control strategies
    • Improved diagnostic reagents and methods
    • Development of potential vaccine candidates
    • Risk factor identification using landscape ecology and epidemiology
       

    Return to top of page    

     

    CDC Home | Search | Health Topics A-Z |

    This page last reviewed June 22, 2001

    | Division of Vector-Borne Infectious Diseases  |
    National Center for Infectious Diseases |
    Centers for Disease Control and Prevention |
    P.
    (Source: excerpt from Plague Epidemiology: DVBID_1) ... Annually, 1­40 cases of plague were reported (average 13 cases) by western states in 1971­1995. (Source: excerpt from Facts About Plague: CDC-OC)

    Worldwide prevalence of Plague:

    Globally, the World Health Organization reports 1,000 to 3,000 cases of plague every year. (Source: excerpt from CDC Plague Home Page: DVBID)

    Prevelance of Plague discussion:

    In the United States, the last urban plague epidemic occurred in Los Angeles in 1924-25. Since then, human plague in the United States has occurred as mostly scattered cases in rural areas (an average of 10 to 15 persons each year). Globally, the World Health Organization reports 1,000 to 3,000 cases of plague every year. In North America, plague is found in certain animals and their fleas from the Pacific Coast to the Great Plains, and from southwestern Canada to Mexico. Most human cases in the United States occur in two regions: 1) northern New Mexico, northern Arizona, and southern Colorado; and 2) California, southern Oregon, and far western Nevada. Plague also exists in Africa, Asia, and South America (see map). (Source: excerpt from CDC Plague Home Page: DVBID)

    Incidence statistics for Plague:

    The following statistics relate to the incidence of Plague:

    • 0 new cases of plague per 100,000 population was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW)
    • 0 new cases of plague was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW)
    • 10 registered cases in Peru 2001 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
    • 2 registered cases in the US 2001 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
    • 2 registered cases in Brazil 2000 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
    • more statistics...»

    More Statistics about Plague:

  • Hospitalization statistics
  • All statistics for Plague

    Prevalence/Incidence of Plague: Online Medical Books

    16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Plague.

    Plague: Causes and incidence
    (Professional Guide to Diseases (Eighth Edition))

    Plague is usually transmitted to humans through the bite of a flea from an infected rodent host, such as a rat, squirrel, prairie dog, or hare. (See Carrier of bubonic plague.) Occasionally, transmission occurs from handling infected animals or their tissues. Bubonic plague is notorious for the historic pandemics in Europe and Asia during the Middle Ages, which in some areas killed up to two-thirds of the population. This form is rarely transmitted from person to person. However, the untreated bubonic form may progress to a secondary pneumonic form, which is transmitted by contaminated respiratory droplets (coughing) and is highly contagious. In the United States, the primary pneumonic form usually occurs after inhalation of Y. pestis in a laboratory.

    Sylvatic (wild rodent) plague remains endemic in South America, the Near East, central and Southeast Asia, north central and southern Africa, Mexico, and western United States and Canada. In the United States, its incidence has been rising, a possible reflection of different bacterial strains or environmental changes that favor rodent growth in certain areas. Plague tends to occur between May and September; between October and February it usually occurs in hunters who skin wild animals. One attack confers permanent immunity.

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Diseases (Eighth Edition), 2005

    Plague: Plague - epidemiology
    (The 5-Minute Pediatric Consult)

    • >50% of the contemporary cases of plague occur in persons <20 years of age, possibly because of an increased tendency for children to encounter small animals and rodents when living in rural areas.
    • A large proportion of the cases in the US have occurred in the Southwest throughout the year but most commonly during the spring and summer.
    • Bubonic plague:
      • 75% of plague cases worldwide
    • An outbreak of the pneumonic plague has been reported recently in India; however, the identification of the specific causative organism has been called into question.
    • 13 cases of plague occurred in the US in 2006 including 5 septicemic and 8 bubonic cases. 2 developed plague pneumonia.
    • No cases of person-to-person transmissions of plague pneumonia have been reported in the US since 1925.
    >

    » READ BOOK EXCERPT ONLINE »

    Source: The 5-Minute Pediatric Consult, 2008

    About prevalence and incidence statistics:

    The term 'prevalence' of Plague usually refers to the estimated population of people who are managing Plague at any given time. The term 'incidence' of Plague refers to the annual diagnosis rate, or the number of new cases of Plague diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.


     » Next page: Videos related to Plague

    Rate This Website

    What do you think about the features of this website? Take our user survey and have your say:

    Website User Survey

    Medical Tools & Articles:

    Next articles:

    Tools & Services:

    Medical Articles:

    Forums & Message Boards

  •  
    HONcode We subscribe to the HONcode principles

    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise