Prevalence and Incidence of Plague
Plague: Rare Disease
Plague is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Plague, or a subtype of Plague,
affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Plague as a "rare disease".
More information about Plague is available from Orphanet
Plague Prevalence: Book Excerpts
Incidence (annual) of Plague:
9 annual cases of plague notified in USA 1999 (MMWR 1999) ... see also overview of Plague.
Incidence Rate:
approx 1 in 30,222,221 or 0.00% or 9 people in USA [Source statistic for calcuation: "9 annual cases of plague notified in USA 1999 (MMWR 1999)" -- see also general information about data sources]
Incidence extrapolations for USA for Plague:
9 per year,
0 per month,
0 per week,
0 per day,
0 per hour,
0 per minute,
0 per second.
[Source statistic for calculation: "9 annual cases of plague notified in USA 1999 (MMWR 1999)" -- see also general information about data sources]
Prevalance of Plague:
In the U.S., 1
to 40 cases reported annually (avg = 13 cases) by western states, 1971-1995
Worldwide, 2861
cases reported by 10 countries to WHO in 1995
SEQUELAE
- Rare, consequences
of disseminated intravascular coagulation, lung damage
- Mortality 50-90%
if untreated; 15% when diagnosed and treated
COSTS
TRANSMISSION
- Flea-borne, from
infected rodents to humans
- Direct contact
with infected tissues or fluids from handling sick or dead animals
- Respiratory droplets
from cats and humans with pneumonic plague
RESERVOIRS
- Primarily wild
rodents in U.S. (especially rock squirrels, ground squirrels, prairie
dogs, other burrowing rodents)
- Commensal rats
may be important elsewhere
RISK GROUPS
- In the U.S., persons
exposed to rodent fleas, wild rodents, or other susceptible animals
in enzootic areas of western states
- Most cases occur
in southwestern states of NM, AZ, CO, and in CA
- Highest rates in
Native Americans, especially Navajos; other risk groups: hunters; veterinarians
and pet owners handling infected cats; campers or hikers entering areas
with outbreaks of animal plague
SURVEILLANCE
- National Notifiable
Disease Surveillance System (NNDSS) for animal plague surveillance,
for reports of human cases, and laboratory testing of fleas, animal
tissues and serum specimens, and serosurveys of carnivores
- CDC, Fort Collins,
is a WHO Collaborating Center for Reference and Research on Plague Control,
and reports all human plague cases in the U.S. to WHO
OPPORTUNITIES
- Increased self-sufficiency
of state and county public health labs
- Expanded active
surveillance through carnivore serosurveys and application of geographic
information systems (GIS) to surveillance programs
- Increased education
of public and health professionals
- Collaborative applied
research on plague prevention and control with other federal, state,
and local health agencies, including application of GIS to surveillance
RESEARCH
- Ecology-based prevention
and control strategies
- Improved diagnostic
reagents and methods
- Development of
potential vaccine candidates
- Risk factor identification
using landscape ecology and epidemiology
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P. (Source: excerpt from Plague Epidemiology: DVBID_1)
...
Annually, 140 cases of plague were reported (average 13 cases)
by western states in 19711995. (Source: excerpt from Facts About Plague: CDC-OC)
Worldwide prevalence of Plague:
Globally,
the World Health Organization reports 1,000 to 3,000 cases of plague every
year. (Source: excerpt from CDC Plague Home Page: DVBID)
Prevelance of Plague discussion:
In the United
States, the last urban plague epidemic occurred in Los Angeles in 1924-25.
Since then, human plague in the United States has occurred as mostly scattered
cases in rural areas (an average of 10 to 15 persons each year). Globally,
the World Health Organization reports 1,000 to 3,000 cases of plague every
year. In North America, plague is found in certain animals and their fleas
from the Pacific Coast to the Great Plains, and from southwestern Canada
to Mexico. Most human cases in the United States occur in two regions:
1) northern New Mexico, northern Arizona, and southern Colorado; and 2)
California, southern Oregon, and far western Nevada. Plague also exists
in Africa, Asia, and South America (see map). (Source: excerpt from CDC Plague Home Page: DVBID)
Incidence statistics for Plague:
The following statistics relate to the incidence of Plague:
- 0 new cases of plague per 100,000 population was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW)
- 0 new cases of plague was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW)
- 10 registered cases in Peru 2001 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
- 2 registered cases in the US 2001 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
- 2 registered cases in Brazil 2000 (Regional Core Health Data Initiative, Pan American Health Organisation, 2003)
- more statistics...»
More Statistics about Plague:
Hospitalization statistics
All statistics for Plague
Prevalence/Incidence of Plague: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Plague.
Plague:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Plague is usually transmitted to humans through the bite of a flea from an infected rodent host, such as a rat, squirrel, prairie dog, or hare. (See Carrier of bubonic plague.) Occasionally, transmission occurs from handling infected animals or their tissues. Bubonic plague is notorious for the historic pandemics in Europe and Asia during the Middle Ages, which in some areas killed up to two-thirds of the population. This form is rarely transmitted from person to person. However, the untreated bubonic form may progress to a secondary pneumonic form, which is transmitted by contaminated respiratory droplets (coughing) and is highly contagious. In the United States, the primary pneumonic form usually occurs after inhalation of Y. pestis in a laboratory.
Sylvatic (wild rodent) plague remains endemic in South America, the Near East, central and Southeast Asia, north central and southern Africa, Mexico, and western United States and Canada. In the United States, its incidence has been rising, a possible reflection of different bacterial strains or environmental changes that favor rodent growth in certain areas. Plague tends to occur between May and September; between October and February it usually occurs in hunters who skin wild animals. One attack confers permanent immunity.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Plague:
Plague - epidemiology
(The 5-Minute Pediatric Consult)
- >50% of the contemporary cases of plague occur in persons <20 years of age, possibly because of an increased tendency for children to encounter small animals and rodents when living in rural areas.
- A large proportion of the cases in the US have occurred in the Southwest throughout the year but most commonly during the spring and summer.
- Bubonic plague:
- 75% of plague cases worldwide
- An outbreak of the pneumonic plague has been reported recently in India; however, the identification of the specific causative organism has been called into question.
- 13 cases of plague occurred in the US in 2006 including 5 septicemic and 8 bubonic cases. 2 developed plague pneumonia.
- No cases of person-to-person transmissions of plague pneumonia have been reported in the US since 1925.
>
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Plague usually refers to the estimated population
of people who are managing Plague at any given time.
The term 'incidence' of Plague refers to the annual diagnosis rate,
or the number of new cases of Plague diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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