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Diseases » Pleural effusion » Clinical Trials

Clinical Trials for Pleural effusion

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Pleural effusion is grouped into the following categories:-

View by trial name

View by drugs used in Pleural effusion clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Pleural effusion:

Multiple Biomarkers in Undiagnosed Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006)
Talc in Treating Patients With Malignant Pleural Effusion - This study is no longer recruiting patients (Current: 23 Nov 2006) - talc
Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions - This study is no longer recruiting patients (Current: 23 Nov 2006) - bleomycin,doxycycline,talc
ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006) - ILX-295501
Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura - This study has been completed (Current: 23 Nov 2006) - decitabine
Non-Small Cell Lung Cancer Registry - This study is no longer recruiting patients (Current: 23 Nov 2006)
Phase II Randomized, Open-Label Study of Cetuximab and Bevacizumab in Combination With Paclitaxel and Carboplatin in Patients With Stage IIIb/IV NSCLC - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Erbitux (cetuximab)
Use of the Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in the Diagnosis of Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006)
Use of Procalcitonin in the Diagnosis of Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006)
Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - talc
Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer - This study has been completed (Current: 23 Nov 2006) - bortezomib,carboplatin,gemcitabine
Surgery and Intrapleural Docetaxel in Treating Patients With Malignant Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006) - docetaxel
Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion - This study is currently recruiting patients (Current: 23 Nov 2006)
A Quality of Life Study re Management of Malignant Pleural Effusions - This study is currently recruiting patients (Current: 23 Nov 2006)
Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion - This study is currently recruiting patients (Current: 23 Nov 2006) - Alteplase
Effects of Carboplatin and Gemcitabine on Stage IIIB Pleural Effusion and Stage IV Lung Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - Carboplatin,Gemcitabine,Dexamethasone
Gene Therapy for Pleural Malignancies - This study is currently recruiting patients (Current: 23 Nov 2006)
Ecteinascidin 743 in Treating Adults With Advanced Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006) - ecteinascidin 743
Penclomedine in Treating Patients With Solid Tumors or Lymphoma - This study has been completed (Current: 23 Nov 2006) - penclomedine
Decitabine in Treating Patients With Melanoma or Other Advanced Cancer - This study has been completed (Current: 23 Nov 2006) - decitabine
Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - fluorouracil,leucovorin calcium,topotecan
L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-778,123
Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - interferon alfa,interleukin-12
Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - fluorouracil,leucovorin calcium,SCH 66336
Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - amifostine,carboplatin,cyclophosphamide,sargramostim
Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-778,123,L-778,123/paclitaxel,paclitaxel
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of the HER2/Neu Protein - This study is no longer recruiting patients (Current: 23 Nov 2006) - interleukin-12,trastuzumab
Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer - This study has been completed (Current: 23 Nov 2006) - R115777,R115777/trastuzumab,trastuzumab
Treatment With Octreotide in Patients With Lymphangioleiomyomatosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Octreotide
Combination Chemotherapy in Treating Patients With Advanced Lung Cancer, Esophageal Cancer, Pleural Mesothelioma, or Lung Metastases - This study is currently recruiting patients (Current: 23 Nov 2006) - celecoxib,decitabine,romidepsin
Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions - This study is no longer recruiting patients (Current: 23 Nov 2006) - BG00001
FR901228 and Flavopiridol in Treating Patients With Advanced Lung, Esophageal, or Pleural Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - flavopiridol,romidepsin
Corticosteroids in the Treatment of Tuberculous Pleurisy - This study is currently recruiting patients (Current: 23 Nov 2006) - prednisolone
Safety and Effectiveness of ABT-510 Plus Combination Chemotherapy in Subjects With Non-Small Cell Lung Cancer (NSCLC) - This study is no longer recruiting patients (Current: 23 Nov 2006) - ABT-510/Thrombospondin-1 mimetic,Carboplatin/Taxol

Drugs used in Clinical Trials for Pleural effusion

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Pleural effusion: