Diseases » Polio » Clinical Trials

Clinical Trials for Polio

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Polio is grouped into the following categories:-

View by trial name

View by drugs used in Polio clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Polio:

Immunogenicity and Safety of Imovax Polio in Chinese Infants Compared to Local OPV - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of "Post-Polio Syndrome" - This study has been completed (Current: 23 Nov 2006)
Immunogenicity and Safety of Pentaxim in South African Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand - This study is no longer recruiting patients (Current: 23 Nov 2006)
Safety of Imovax Polio in Chinese Infants and Children - This study is no longer recruiting patients (Current: 23 Nov 2006)
Immunogenicity Study of Antibody Persistence and Booster Effect of PENTAXIM at 18 Months in Healthy Argentinean Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Post-Marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine - This study is currently recruiting patients (Current: 23 Nov 2006)
Study to Compare Pediacel to Infanrix-IPV+Hib When Both Are Co-Administered With Prevenar in Infants and Toddlers - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of Menactra in Children Aged 4 to 6 Years When Administered Concomitantly With a Fifth Dose of DAPTACEL - This study is currently recruiting patients (Current: 23 Nov 2006)
Immunogenicity and Safety of Tetraxim Versus Local DTP + IPV - This study is currently recruiting patients (Current: 23 Nov 2006)
Pentavalent DTaP-Hep B-IPV - This study has been suspended (Current: 23 Nov 2006)
Comparison of Immune Response Using 2 Vaccination Schedules Using Inactivated Polio Vaccine - This study has been completed (Current: 23 Nov 2006)
Immunogenicity and Safety of Pentaxim in an Indian Population - This study is currently recruiting patients (Current: 23 Nov 2006)
Immunogenicity of DTaP-IPV-HB-PRP~T Combined Vaccine Compared With PENTAXIM and ENGERIX B at 2-3-4 Months Schedule - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Comparison of DTaP IPV HB PRP~T Combined Vaccine to CombAct-HIB Concomitantly Given With Engerix B Paediatric and OPV - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar - This study is currently recruiting patients (Current: 23 Nov 2006)
Comparison of a DTaP-IPV-HB-PRP~T Combined Vaccine to Infanrix-Hexa, When Administered With Prevnar in Thai Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of an Investigational Vaccine in Healthy Infants in Taiwan - This study is no longer recruiting patients (Current: 23 Nov 2006)
Pilot Study Freeze and Transport Immune Cells - This study is no longer recruiting patients (Current: 23 Nov 2006)
Comparison of Safety and Immunogenicity of Pediacel and Infanrix IPV+Hib (Penta) Given in a 3 Dose Schedule in Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Compare Immunogenicity & Safety of 2 Formulations of GSK Biologicals DTPa-HBV-IPV/Hib Vaccine Given in Healthy Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Concomitant Use of Gardasil (V501, Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis and Poliomyelitis Vaccine in Adolescents - This study is no longer recruiting patients (Current: 23 Nov 2006)
Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age. - This study is currently recruiting patients (Current: 23 Nov 2006)
Post-Poliosyndrome Treated With Intravenous Immunoglobulin (IvIg) - This study has been completed (Current: 23 Nov 2006) - IvIg
Assessment of the Immunogenicity and Safety of PENTAXIM in Philippines - This study is no longer recruiting patients (Current: 23 Nov 2006)
Safety and Immune Response of Different Pediatric Combination Vaccines. - This study is currently recruiting patients (Current: 23 Nov 2006)
To Evaluate Immunogenicity & Safety of GSK Bios DTPa-HBV-IPV/Hib (Mixed Vaccine) and DTPa-IPV/Hib + HBV Vaccines - This study has been completed (Current: 23 Nov 2006)
Efficacy and Safety of Xepol (Human Immunoglobulin) in Subjects With Post-Polio Syndrome (PPS) - This study has been completed (Current: 23 Nov 2006) - Xepol
Modafinil to Treat Fatigue in Post-Polio Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006) - Modafinil
Electromyography to Diagnose Neuromuscular Disorders - This study has been completed (Current: 23 Nov 2006)
A Study to Assess the Feasibility of an Acellular Pertussis Vaccine (Pa) Given Soon After Birth, Followed by 3-Dose Primary Vaccination With the DTPa-HBV-IPV/Hib Vaccine. A Booster Dose of DTPa-HBV-IPV/Hib Will Be Given in the 2nd Year of Life. - This study has been completed (Current: 23 Nov 2006)
Brain Physiology in Polio Survivors - This study is currently recruiting patients (Current: 23 Nov 2006)
Vaccination of Children Following Allogeneic Stem Cell Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
Safety of DTaP-IPV-HB-PRP~T Combined Vaccine Compared to Tritanrix-HepB/Hib and OPV Given at Age 2, 4, and 6 Months. - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Immunogenicity & Safety of GSKs Combined DTPa-HBV-IPV/Hib Vaccine in Indian Infants at 2 Diff Vaccination Schedules - This study is no longer recruiting patients (Current: 23 Nov 2006)
Study to Compare Booster Vaccination With Pediacel to Infanrix Hexa When Both Are Co-Administered With Prevenar - This study is currently recruiting patients (Current: 23 Nov 2006)
Evaluation of the Immunogenicity, Safety and Reactogenicity of the Combined DTPa-IPV Vaccine in Healthy Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of Inactivated Poliovirus Vaccine Given at an Earlier Schedule With Shorter Intervals - This study has been completed (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Polio

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Polio: