Causes of Pregnancy toxemia /hypertension
Causes of Pregnancy toxemia /hypertension (Diseases Database):
The follow list shows some of the possible medical causes of Pregnancy toxemia /hypertension
that are listed by the Diseases Database:
Source: Diseases Database
Pregnancy toxemia /hypertension Causes: Book Excerpts
Pregnancy toxemia /hypertension as a complication of other conditions:
Other conditions that might have
Pregnancy toxemia /hypertension as a complication may,
potentially, be an underlying cause of Pregnancy toxemia /hypertension.
Our database lists the following as having
Pregnancy toxemia /hypertension as a complication of that condition:
Pregnancy toxemia /hypertension as a symptom:
Conditions listing Pregnancy toxemia /hypertension
as a symptom may also be potential underlying causes of Pregnancy toxemia /hypertension.
Our database lists the following as having
Pregnancy toxemia /hypertension as a symptom of that condition:
What causes Pregnancy toxemia /hypertension?
Article excerpts about the
causes of Pregnancy toxemia /hypertension:
REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI (Excerpt)
Preeclampsia is a pregnancy-specific syndrome in which there is
increased vascular responsiveness to vasoconstrictor stimuli and activation of
the coagulation cascade. The initial insult appears to be reduced placental
perfusion frequently due to abnormal implantation of the blastocyst and abnormal
remodeling of the maternal vessels that supply the intervillous space. These
phenomena lead to decreased perfusion of the placenta and are considered by some
to represent stage one of a two-stage process. Stage two refers to development
of the maternal and fetal syndrome of preeclampsia. At present, the link between
stages is not clear. It is evident that reduced placental perfusion does not
always result in the maternal syndrome, and that maternal factors also are
required. Genetic polymorphisms, fetal signals, and increased hypoxia at the
maternal fetal interface likely play a role in the interaction of reduced
placental perfusion and the maternal constitution to generate the preeclampsia
syndrome. Many of these predisposing maternal factors are also risk factors for
cardiovascular disease in later life. For example, coagulation abnormalities,
dyslipidemia, increased inflammatory markers, and evidence of oxidative stress
and endothelial activation are associated with increased cardiovascular disease
risk, and also are detectable in women who develop preeclampsia, occurring
before the overt clinical symptoms appear.
(Source: excerpt from REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI)
REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI (Excerpt)
Some women
with preeclampsia also have autoimmune disorders. There are several promising
animal models that suggest a role for inflammation in the pathogenesis of
preeclampsia. There is evidence of activation of the inflammatory response in
pregnancy that is further increased in preeclampsia. Researchers have thus been
led to consider inflammatory markers both as important in the epidemiology of
preeclampsia, and as a potential link between preeclampsia and future
cardiovascular disease. (Source: excerpt from REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI)
REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI (Excerpt)
Many of the features of preeclampsia mimic the insulin resistance
or metabolic syndrome, and insulin resistance is a prominent feature of
preeclampsia. These findings provide evidence of a link between preeclampsia and
future cardiovascular disease, although the direction of causation is unclear at
present.
(Source: excerpt from REPORT of the WORKING GROUP on RESEARCH on HYPERTENSION DURING PREGNANCY: NHLBI)
Medical news summaries relating to Pregnancy toxemia /hypertension:
The following medical news items are relevant to causes of Pregnancy toxemia /hypertension:
Related information on causes of Pregnancy toxemia /hypertension:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Pregnancy toxemia /hypertension may be found in:
Causes of Pregnancy toxemia /hypertension: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Pregnancy toxemia /hypertension.
Pregnancy-induced hypertension:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
The cause of pregnancy-induced hypertension is unknown, but geographic, ethnic, racial, nutritional, immunologic, and familial factors and pre-existing vascular disease may contribute to its development. Age is also a factor. Primiparas who are older than age 35 are at higher risk for preeclampsia.
Preeclampsia develops in about 7% of pregnancies. Incidence is significantly higher in low socioeconomic groups. About 5% of females with preeclampsia develop eclampsia; of these, about 15% die from PIH itself or its complications. Fetal mortality is high due to the increased incidence of premature delivery and uteroplacental insufficiency.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Hypertension, pregnancy-induced:
Causes
(Handbook of Diseases)
The cause of PIH is unknown, but it appears to be related to inadequate prenatal care (especially poor nutrition), parity (more prevalent in primigravidas), multiple pregnancies, preexisting diabetes mellitus, and hypertension.
Age is also a factor. Adolescents and primiparas over age 35 are at higher risk for preeclampsia. Other theories postulate a long list of potential toxic sources, such as autolysis of placental infarcts, autointoxication, uremia, maternal sensitization to total proteins, and pyelonephritis.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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