Causes of Primary biliary cirrhosis
List of causes of Primary biliary cirrhosis
Following is a list of causes or underlying conditions
(see also Misdiagnosis of underlying causes of Primary biliary cirrhosis)
that could possibly cause Primary biliary cirrhosis includes:
- Unknown etiology
- Genetic factors
- Autoimmune in nature
Primary biliary cirrhosis Causes: Book Excerpts
Primary biliary cirrhosis as a complication of other conditions:
Other conditions that might have
Primary biliary cirrhosis as a complication may,
potentially, be an underlying cause of Primary biliary cirrhosis.
Our database lists the following as having
Primary biliary cirrhosis as a complication of that condition:
What causes Primary biliary cirrhosis?
Causes: Primary biliary cirrhosis:
The cause of primary biliary cirrhosis is unknown.
(Source: excerpt from Primary Biliary Cirrhosis: NIDDK)
Medical news summaries relating to Primary biliary cirrhosis:
The following medical news items are relevant to causes of Primary biliary cirrhosis:
Related information on causes of Primary biliary cirrhosis:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Primary biliary cirrhosis may be found in:
Causes of Primary biliary cirrhosis: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Primary biliary cirrhosis.
Ascites:
Differential Diagnosis
(In A Page: Pediatric Signs and Symptoms)
Hepatic, resulting in portal hypertension
–Hepatic cirrhosis: Extrahepatic biliary atresia, α-1-antitrypsin deficiency,
galactosemia, tyrosinemia
–Portal vein thrombosis
–Cavernous transformation: Catheterization,
dehydration, clotting disorder, omphalitis
–Budd-Chiari syndrome, due to neoplasm,
collagen disease, hypercoagulopathy, OCP
–Arteriovenous fistula
–Fulminant hepatic failure (drugs, virus)
–Congenital hepatic fibrosis
–Lysosomal storage diseases (e.g., Gaucher)
-
Bile ascites (bile peritonitis): Spontaneous rupture of the common bile duct
-
Renal
–Nephrotic syndrome
–Urinary ascites (due to bladder rupture)
–Obstructive uropathy: Congenital ascites may
be seen with bilateral hydronephrosis
-
Peritoneal dialysis
-
Cardiac
–Congestive heart failure
–Chronic constrictive pericarditis
–Inferior vena cava web
–Erythroblastosis fetalis
-
Peritonitis
–Tuberculous peritonitis
–Schistosomiasis (Mansoni)
–Tularemia
–Abscess
-
Gastrointestinal disorders
–Infarcted bowel
–Bowel perforation
–Pancreatitis, ruptured pancreatic duct
–Protein-losing gastroenteropathy
-
Chylous ascites
–Collection of lymph within the abdominal cavity; secondary to lymphatic obstruction from trauma, surgery, tumor, tuberculosis, or filariasis
-
Gynecologic
–Ovarian tumors, cyst torsion or rupture
-
Malignancy
–Leukemia, lymphoma, neuroblastoma
-
Systemic lupus erythromatosus
-
Ventriculoperitoneal shunt
-
Hypothyroidism
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Cirrhosis and fibrosis:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
These clinical types of cirrhosis reflect its diverse etiology:
❑ Portal, nutritional, or alcoholic (Laennec’s) cirrhosis, the most common type, occurs in 30% to 50% of cirrhotic patients, up to 90% of whom have a history of alcoholism. Liver damage results from malnutrition, especially of dietary protein, and chronic alcohol ingestion. Fibrous tissue forms in portal areas and around central veins.
❑ Biliary cirrhosis (15% to 20% of patients) results from injury or prolonged obstruction.
❑ Postnecrotic (posthepatic) cirrhosis (10% to 30% of patients) stems from various types of hepatitis.
❑ Pigment cirrhosis (5% to 10% of patients) may result from disorders such as hemochromatosis.
❑ Cardiac cirrhosis (rare) refers to liver damage caused by right-sided heart failure.
❑ Idiopathic cirrhosis (about 10% of patients) has no known cause.
Noncirrhotic fibrosis may result from schistosomiasis or congenital hepatic fibrosis or may be idiopathic.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Cirrhosis:
Causes
(Handbook of Diseases)
Cirrhosis has various causes, depending on the type.
Hepatocellular disease
Postnecrotic cirrhosis accounts for 10% to 30% of patients and stems from various types of hepatitis (such as types A, B, C, D viral hepatitis) or toxic exposures.
Laënnec’s cirrhosis — also called portal, nutritional, or alcoholic cirrhosis — is the most common type and is commonly caused by hepatitis C. Liver damage results from malnutrition (especially dietary protein) and overuse of alcohol. Fibrous tissue forms in portal areas and around central veins.
Autoimmune disease, such as sarcoidosis and chronic inflammatory bowel disease, may result in cirrhosis.
Cholestatic diseases
Cholestatic diseases include diseases of the biliary tree (biliary cirrhosis resulting from bile duct diseases suppressing bile flow) and sclerosing cholangitis.
Metabolic diseases
Metabolic diseases include disorders such as Wilson’s disease, alpha1-antitrypsin deficiency, and hemochromatosis (pigment cirrhosis).
Other types of cirrhosis
Other types of cirrhosis include Budd-Chiari syndrome, cardiac cirrhosis, and cryptogenic cirrhosis. Cardiac cirrhosis is rare; the liver damage results from right-sided heart failure. Cryptogenic refers to cirrhosis of unknown cause.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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