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Symptoms of Primary biliary cirrhosis

Symptoms of Primary biliary cirrhosis

The list of signs and symptoms mentioned in various sources for Primary biliary cirrhosis includes the 40 symptoms listed below:

Research symptoms & diagnosis of Primary biliary cirrhosis:

Primary biliary cirrhosis: Complications

Review medical complications possibly associated with Primary biliary cirrhosis:

Primary biliary cirrhosis Symptoms: Book Excerpts

Diagnostic Testing

Diagnostic testing of medical conditions related to Primary biliary cirrhosis:

Research More About Primary biliary cirrhosis

Do I have Primary biliary cirrhosis?

Home Diagnostic Testing

Home medical tests related to Primary biliary cirrhosis:

Wrongly Diagnosed with Primary biliary cirrhosis?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Primary biliary cirrhosis includes:

See the full list of 10 alternative diagnoses for Primary biliary cirrhosis

Primary biliary cirrhosis: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

More about symptoms of Primary biliary cirrhosis:

More information about symptoms of Primary biliary cirrhosis and related conditions:

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

Medical Books Online about Primary biliary cirrhosis

Medical Books Excerpts Excerpts of published medical book chapters related to Primary biliary cirrhosis are available from published medical books for more detailed information about Primary biliary cirrhosis.

Medical Books Excerpts
  • ASCITES
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • Ascites
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Ascites
  • "A Pocket Manual of Differential Diagnosis" (1999)
  • Ascites
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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Patient Surveys for Primary biliary cirrhosis

Symptoms of Primary biliary cirrhosis: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of Primary biliary cirrhosis.


Cirrhosis and fibrosis: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Clinical manifestations of cirrhosis and fibrosis are similar for all types, regardless of the cause. Early indications are vague, but usually include GI signs and symptoms (anorexia, indigestion, nausea, vomiting, constipation, or diarrhea) and a dull abdominal ache. Major and late signs and symptoms develop as a result of hepatic insufficiency and portal hypertension:

❑ Respiratory — pleural effusion and limited thoracic expansion due to abdominal ascites, interfering with efficient gas exchange and leading to hypoxia

❑ Central nervous system — progressive signs or symptoms of hepatic encephalopathy — lethargy, mental changes, slurred speech, asterixis (flapping tremor), peripheral neuritis, paranoia, hallucinations, extreme obtundation, and coma

❑ Hematologic — bleeding tendencies (nosebleeds, easy bruising, and bleeding gums) and anemia

❑ Endocrine — testicular atrophy, menstrual irregularities, gynecomastia, and loss of chest and axillary hair

❑ Skin — severe pruritus, extreme dryness, poor tissue turgor, abnormal pigmentation, spider angiomas, palmar erythema, and possibly jaundice

❑ Hepatic — jaundice, hepatomegaly, ascites, edema of the legs, hepatic encephalopathy, and hepatorenal syndrome comprise the other major effects of full-fledged cirrhosis

❑ Miscellaneous — musty breath, enlarged superficial abdominal veins, muscle atrophy, pain in the right upper abdominal quadrant that worsens when the patient sits up or leans forward, palpable liver or spleen, and temperature of 101° to 103° F (38.3° to 39.4° C). Bleeding from esophageal varices results from portal hypertension.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Cirrhosis: Signs and symptoms
(Handbook of Diseases)

Signs and symptoms of cirrhosis and fibrosis are similar for all types, regardless of cause. Early indications are insidious and vague but usually include weakness, fatigue, muscle cramps, weight loss, GI signs and symptoms (anorexia, indigestion, nausea, vomiting, constipation, diarrhea), and abdominal pain (which may be attributed to an enlarged liver).

Major and late signs and symptoms develop as a result of hepatic insufficiency and portal hypertension and include the following:

respiratory — pleural effusion and limited thoracic expansion because of abdominal ascites, interfering with efficient gas exchange and leading to hypoxia

central nervous system — progressive signs and symptoms of hepatic encephalopathy: lethargy, mental changes, slurred speech, asterixis (flapping tremor), peripheral neuritis, paranoia, hallucinations, extreme obtundation, and coma

hematologic — bleeding tendencies (nosebleeds, easy bruising, bleeding gums), anemia, and hematemesis

endocrine — testicular atrophy, menstrual irregularities, gynecomastia, loss of chest and axillary hair, loss of libido, and sterility

skin — severe pruritus, extreme dryness, poor tissue turgor, abnormal pigmentation, spider nevi (on upper half of body), palmar erythema, jaundice, and peripheral edema

hepatic — jaundice, hepatomegaly, ascites, edema of the legs, hepatic encephalopathy, and hepatorenal syndrome constitute the other major effects of full-fledged cirrhosis

miscellaneous — musty breath, enlarged superficial abdominal veins, muscle atrophy, pain in the right upper abdominal quadrant that worsens when the patient sits up or leans forward, splenomegaly, and wasting appearance of chronic illness. Fever may be present and usually associated with portal hepatitis, spontaneous bacterial peritonitis, or cholangitis. Bleeding from esophageal and rectal varices results from portal hypertension.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Cirrhosis: Cirrhosis - signs & symptoms
(The 5-Minute Pediatric Consult)

  • Compensated (latent) cirrhosis: Asymptomatic, with no signs or symptoms of liver disease. Discovered incidentally either during routine physical examinations with an enlarged liver and/or palpable spleen, or as a result of an investigation for an unrelated condition.
  • Decompensated (active) cirrhosis: As cirrhosis progresses, overt signs and symptoms may occur including failure to thrive, muscle weakness, fatigue, fever, jaundice, pruritus, edema, abdominal pain, ascites, steatorrhea, and spontaneous bleeding (i.e., epistaxis) or bruising. This stage may also present with acute, precipitous liver failure or a life-threatening complication such as an esophageal variceal hemorrhage.

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

Article Excerpts About Symptoms of Primary biliary cirrhosis:

The most common symptoms of primary biliary cirrhosis are itchy skin and fatigue. Other symptoms include jaundice (yellowing of the eyes and skin), cholesterol deposits on the skin, fluid retention, and dry eyes or mouth. Some people with primary biliary cirrhosis also have osteoporosis, arthritis, and thyroid problems. (Source: excerpt from Primary Biliary Cirrhosis: NIDDK)

Primary biliary cirrhosis as a Cause of Symptoms or Medical Conditions

When considering symptoms of Primary biliary cirrhosis, it is also important to consider Primary biliary cirrhosis as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Primary biliary cirrhosis may cause:

- (Source - Diseases Database)

Primary biliary cirrhosis: Onset and Incubation

Onset of Primary biliary cirrhosis: Primary biliary cirrhosis mostly affects middle-aged women, with a mean age of 39 years. Onset usually occurs in persons aged 30-65 years.

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

Full list of premium articles on symptoms and diagnosis

About signs and symptoms of Primary biliary cirrhosis:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Primary biliary cirrhosis. This signs and symptoms information for Primary biliary cirrhosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Primary biliary cirrhosis signs or Primary biliary cirrhosis symptoms. Furthermore, signs and symptoms of Primary biliary cirrhosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Primary biliary cirrhosis symptoms.


 » Next page: Diagnostic Tests for Primary biliary cirrhosis

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