Causes of Primary Immune Deficiency
Primary Immune Deficiency Causes: Book Excerpts
Primary Immune Deficiency as a symptom:
Conditions listing Primary Immune Deficiency
as a symptom may also be potential underlying causes of Primary Immune Deficiency.
Our database lists the following as having
Primary Immune Deficiency as a symptom of that condition:
Related information on causes of Primary Immune Deficiency:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Primary Immune Deficiency may be found in:
Causes of Primary Immune Deficiency: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Primary Immune Deficiency.
Common variable immunodeficiency:
Causes
(Professional Guide to Diseases (Eighth Edition))
The cause of common variable immunodeficiency is unknown. Most patients have a normal circulating B-cell count but defective synthesis or release of immunoglobulins. Many also exhibit progressive deterioration of T-cell (cell-mediated) immunity revealed by delayed hypersensitivity skin testing.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Severe combined immunodeficiency disease:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes. Many molecular defects such as mutation of the kinase ZAP-70 can cause SCID. X-linked SCID is due to a mutation of a subunit of the interleukin (IL)-2, IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.
SCID affects more males than females. Its estimated incidence is 1 in every 100,000 to 500,000 births. Most untreated patients die from infection within 1 year of birth.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Common variable immunodeficiency:
Causes
(Handbook of Diseases)
Exactly what causes common variable immunodeficiency is unknown. Most patients have a normal circulating B-cell count but defective synthesis or release of immunoglobulins. Many also exhibit progressive deterioration of T-cell (cell-mediated) immunity, which is revealed by delayed hypersensitivity skin testing.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Severe combined immunodeficiency disease:
Causes
(Handbook of Diseases)
SCID is usually transmitted as an autosomal recessive trait, although it may be X-linked. In most cases, the genetic defect seems associated with failure of the stem cell to differentiate into T and B lymphocytes.
Many molecular defects, such as mutation of the kinase ZAP-70, can cause SCID. X-linked SCID results from a mutation of a subunit of the interleukin-2 (IL-2), IL-4, and IL-7 receptors. Less commonly, it results from an enzyme deficiency.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Chronic fatigue and immune dysfunction syndrome:
Causes
(Handbook of Diseases)
Although the cause of CFIDS is unknown, researchers suspect that it may be found in human herpesvirus 6 or in other herpesviruses, enteroviruses, or retroviruses. Rising levels of antibodies to EBV, once thought to implicate EBV infection as the cause of CFIDS, are now considered a result of this disease.
CFIDS may be associated with a reaction to viral illness that’s complicated by dysfunctional immune response and by other factors that may include sex, age, genetic disposition, prior illness, stress, and environment.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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