Cure Research for Primary insomnia

Treatments for Primary insomnia

Treatments to consider for Primary insomnia may include:

Hypnotics and benzodiazepines (BZDs) are the mainstays of short-term treatment of primary insomnia
Stimulus control therapy
Relaxation therapy
Cognitive behaviour therapy
more treatments...»

Medical Research Breakthroughs and Primary insomnia

Circadin for insomnia: Circadin(R), the first melatonin agent approved by the European Medicines Agency (EMEA), is now available for the treatment of primary insomnia. Circadin, sustained-release melatonin, provides natural sleep by increasing the body's own level of this naturally occurring hormone throughout the night. Unlike existing sleep medications, it is not associated with problems such as dependency and poor next day functioning. The trials showed that almost half of patients taking Circadin experienced a significant improvement in quality of sleep, and nearly 40% improved on morning alertness, as measured by the Leeds Sleep Evaluation Questionnaire. Other study endpoints included sleep latency (or time to get to sleep), and a clinically significant reduction in time was found in the Circadin group, similar to that of traditional sleep medications. Circadin mode of action avoids side effects associated with traditional sleep treatments. Clinical studies with Circadin have not shown any risk of rebound insomnia nor any impairment on memory or psychomotor functioning at any point after dosing. Circadin has a positive safety profile and in clinical studies the incidence of adverse events with Circadin was low and even less than with placebo. Adverse effects were generally mild and infrequent and those reported included headache, sore throat, back pain and generalised feelings of weakness. Hence Circadin has heralded a new phase in the treatment of insomnia.