Clinical Trials for Proteinuria
Clinical trials are research studies conducted in an effort to improve overall patient health and care.
Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition.
Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks.
A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.
A brief description of each phase:
- Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
- Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
- Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
- Phase IV: These studies monitor long-term side effects after the treatment has been marketed.
Clinical Trials data for Proteinuria is grouped into the following categories:-
The format for each of the following is:
- The name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
- followed by a list of drug/s, if any, used in the trial
ClinicalTrials.gov has listed the following trials for Proteinuria:
- Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
- Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney - This study has been completed (Current: 23 Nov 2006) - Spironolactone,Irbesartan
- Tarka Vs. Lotrel in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tarka (trandolapril/verapamil),Lotrel (amlodipine/benazepril)
- Effect of Valsartan on Proteinuria in Patients With Hypertension and Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006) - valsartan
- Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency - This study has been terminated (Current: 23 Nov 2006) - Benazepril,Losartan
- Antiproteinuric Agents and Fabry Disease - This study has been completed (Current: 23 Nov 2006)
- Olmesartan Medoxomil and Diabetic Nephropathy - This study has been completed (Current: 23 Nov 2006) - Olmesartan medoxomil,Losartan
- Angiotensin II Blockade - This study is currently recruiting patients (Current: 23 Nov 2006) - Losartan
- Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - losartan and hydrochlorothiazide
- ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial - This study is no longer recruiting patients (Current: 23 Nov 2006) - olmesartan medoxomil
- Treatment Targets for Chronic Hypertension in Pregnancy - This study is currently recruiting patients (Current: 23 Nov 2006) - methyldopa,labetalol,nifedipine,clonidine
- Statins in Proteinuric Nephropathies - This study is currently recruiting patients (Current: 23 Nov 2006) - Statins
- High Doses of Candesartan Cilexetil on the Reduction of Proteinuria - This study is currently recruiting patients (Current: 23 Nov 2006) - candesartan cilexetil
- Impact of Screening Patients With HIV for Kidney Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Anti-Proteinuric Response to ACEI, ARB and Diuretics Combination. - This study is no longer recruiting patients (Current: 23 Nov 2006) - ramipril 5 mg + valsartan 80 mg/day,,ramipril 10 mg + valsartan 160 mg/day,,ramipril 5 mg + valsartan 80 mg/day + increased dosage of furosémide
- Irbesartan Versus Placebo in Combination With Ramipril for Treatment of Albuminuria - This study is no longer recruiting patients (Current: 23 Nov 2006) - Irbesartan,ramipril
- Effects of Amlodipine/Benazepril on Albuminuria in Hypertensive Patients With Type 2 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - amlodipine/benazepril
- Rationale and Design for Shiga Microalbuminuria Reduction Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - Valsartan,Amlodipine
- Higher Dose of Ramipril Versus Addition of Telmisartan-Ramipril in Hypertension and Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - ramipril,ramipril-telmisartan
- Aldosterone and Vascular Disease in Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - mineralocorticoid receptor antagonist
- Stress-Relief Management for Treatment of Late Complications in Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
- Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy - This study is currently recruiting patients (Current: 23 Nov 2006) - XL784
- Once-A-Month Steroid Treatment for Patients With Focal Segmental Glomerulosclerosis - This study has been completed (Current: 23 Nov 2006) - Dexamethasone
- Permeability Factor Protein in Focal Segmental Glomerulosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Cyclophosphamide
- Sirolimus for Focal Segmental Glomerulosclerosis - This study has been completed (Current: 23 Nov 2006) - Sirolimus
- Steroid Treatment for Kidney Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Oral dexamethasone
- Urinary Vitamin C Loss in Diabetic Subjects - This study is currently recruiting patients (Current: 23 Nov 2006)
- Retinoids for Minimal Change Disease and Focal Segmental Glomerulosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Retinoids for Podocyte Disease
- Pirfenidone to Treat Kidney Disease in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
- Effect of Sulodexide in Overt Diabetic Nephropathy - This study is currently recruiting patients (Current: 23 Nov 2006) - Sulodexide
- High Dose Ace Inhibitor Therapy Versus Combination of ACE and ARB Therapy - This study is currently recruiting patients (Current: 23 Nov 2006) - High dose ACE-I vs ARB
- The Effects of Obesity and Protein Intake on the Kidney - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pentoxifylline and Progression of Chronic Kidney Disease in Moderate-to-High Risk Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - Pentoxifylline
- Prospective Evaluation of Proteinuria and Renal Function in Diabetic Patients With Progressive Renal Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosuvastatin,Atorvastatin
- Prospective Evaluation of Proteinuria and Renal Function in Non-Diabetic Patients With Progressive Renal Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosuvastatin,Atorvastatin
- Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy - This study is currently recruiting patients (Current: 23 Nov 2006) - Mycophenolate Mofetil
- Calcitriol in the Treatment of IgA Nephropathy - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Calcitriol
- Delaying the Progression of Diabetic Nephropathy in Pima Indians - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Pioglitazone and Losartan Provides Additional Renoprotection - This study has been completed (Current: 23 Nov 2006) - pioglitazone,losartan
- Inhibition of the Renin Angiotensin System Plus Corticosteroids for the Treatment of Proteinuria in IGA Nephropathy - This study has been completed (Current: 23 Nov 2006) - ENALAPRIL VALSARTAN METHYLPREDNISONE
- TNF Blockade With Remicade in Active Lupus Nephritis WHO Class V (TRIAL ) - This study is currently recruiting patients (Current: 23 Nov 2006) - infliximab,azathioprine
- Correlation of Urinary Kallikrein With Cytokines, Proteinuria and Renal Function in Chronic Renal Disease Patients - This study has been completed (Current: 23 Nov 2006)
- Effects of Rosiglitazone on Renal Hemodynamics and Proteinuria of Type 2 Diabetic Patients With Renal Insufficiency Due to Overt Diabetic Nephropathy - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone
- Study to Evaluate the Efficacy and Safety of Daglutril Compared to Placebo on Top of Losartan in Type 2 Diabetics With Overt Nephropathy and Well Controlled Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006) - Daglutril
The format for each of the following is:
- The drug,
- followed by the name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
ClinicalTrials.gov has listed the following drugs in trials for Proteinuria:
The trial data on this page has been sourced from
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