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Is there a history of chronic blood loss? A history of peptic ulcer, ulcerative colitis, or other causes of chronic GI bleeding would indicate the anemia is most likely due to iron deficiency. Likewise, chronic hypermenorrhea or ... DIAGNOSTIC WORKUP
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Is there weight loss? If there is weight loss, one must consider a neoplasm, endocrine disorders such as hyperthyroidism or diabetes mellitus, malnutrition or malabsorption, and chronic infectious diseases such as tuberculosis or subacute bacterial ... DIAGNOSTIC WORKUP
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What is the blood glucose and serum acetone level? If these are increased, consider diabetic acidosis. If these are normal, consider other causes of acidosis.
What is the bicarbonate level? An increased bicarbonate level points to ... DIAGNOSTIC WORKUP
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... Anemia is defined as a hemoglobin <13.5 g/dL in men or <12.0 g/dL in women. Etiologies are categorized by decreased RBC production, increased RBC destruction, and/or blood loss. Evaluation of anemia begins with an assessment of the MCV to distinguish>>... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Fatigue is a very common, although nonspecific, presenting symptom that refers to the sensation of exhaustion during or after usual activities, or a feeling of inadequate energy to begin these activities. Fatigue is a difficult clinical complaint... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Anemia is decreased concentration of red cells or hemoglobin in the peripheral blood, resulting in decreased oxygen-carrying capacity of blood. It results from blood loss, decreased or failed production of red blood cells, or increased... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Complaints of fatigue indicate a general state of decreased endurance for, or interest in, activities. It is typically associated with tiredness and sleepiness. Depression as a cause of fatigue in adolescents frequently goes undiagnosed.
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For male genital anomalies, the most important consideration is detection of the anomaly before circumcision. A surgical consultation must take place before circumcision, because the treatment plan may involve the use of the foreskin in reconstruction.
Differential Diagnosis
... Workup and Diagnosis ... Treatment
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... In developing a list of diagnostic possibilities in cases of anemia physiology is the key. Anemia may be caused by a decrease in red cell production, a break in the transport system (blood loss), or excessive red cell destruction.
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... The analysis of the causes of weakness depends on a knowledge of both anatomy and biochemistry. Strength depends on an intact healthy muscle, peripheral nerve, and lower and upper motor neuron pathways and a functioning myoneural junction. Thus, general
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... Developing a list of possible causes of acidosis is also best approached by using the physiologic model of production, transport, excretion, or degradation.
ACIDOSIS (DECREASED PH)
Production
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... Fatigue is a feeling of excessive tiredness, a lack of energy, or exhaustion accompanied by a strong desire to rest or sleep. This common symptom is distinct from weakness, which involves the muscles, but may occur with it.
Fatigue is a normal and... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers
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... Resulting from severe constriction of the visual field that leaves only a small central area of sight, tunnel vision is typically described as the sensation of looking through a tunnel or gun barrel. It may be unilateral or bilateral and usually... History and physical examination ... Medical causes ... Special considerations ... Pediatric pointers ... Pictures
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... Distal (Type I)
Pyelonephritis, chronic
Obstructive uropathy
Drugs, toxins
Amphotericin B
Analgesics
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... Aplastic anemias
Congenital
Fanconi's anemia
Drug- or chemical-induced, or both
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... Renal tubular acidosis (RTA) — a syndrome of persistent dehydration, hyperchloremia, hypokalemia, metabolic acidosis, and nephrocalcinosis — results from the kidneys’ inability to conserve bicarbonate. This disorder occurs as distal RTA (Type... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Aplastic, or hypoplastic, anemias result from injury to or destruction of stem cells in bone marrow or the bone marrow matrix, causing pancytopenia (anemia, granulocytopenia, and thrombocytopenia) and bone marrow hypoplasia. Although commonly used interchangeably with... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Folic acid deficiency anemia is a common, slowly progressive, megaloblastic anemia. It usually occurs in infants, adolescents, pregnant and lactating females, alcoholics, elderly people, and people with malignant or intestinal diseases.
Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Iron deficiency anemia is caused by an inadequate supply of iron for optimal formation of red blood cells (RBCs), resulting in smaller (microcytic) cells with less color on staining. Body stores of iron, including plasma iron, decrease, as do levels of transferrin, which binds... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Pernicious anemia, also known as Addison’s anemia, is a megaloblastic anemia characterized by decreased gastric production of hydrochloric acid and deficiency of intrinsic factor (IF), a substance normally secreted by the parietal cells of... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... A congenital hemolytic anemia that occurs primarily but not exclusively in blacks, sickle cell anemia results from a defective hemoglobin (Hb) molecule (HbS) that causes red blood cells (RBCs) to roughen and become sickle-shaped. Such cells impair... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Sideroblastic anemias are a group of heterogenous disorders with a common defect; they fail to use iron in hemoglobin (Hb) synthesis, despite the availability of adequate iron stores. These anemias may be hereditary or acquired; the acquired form,... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Sometimes called chronic Epstein-Barr virus, or myalgic encephalomyelitis, chronic fatigue and immune dysfunction syndrome is typically marked by debilitating fatigue, neurologic abnormalities, and persistent symptoms that suggest chronic... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... The most common congenital malformations of the ureter, bladder, and urethra include duplicated ureter, retrocaval ureter, ectopic orifice of the ureter, stricture or stenosis of the ureter, ureterocele, exstrophy of the bladder, congenital bladder diverticulum,... Causes ... Special considerations ... Pictures
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... Fatigue is a feeling of excessive tiredness, lack of energy, or exhaustion accompanied by a strong desire to rest or sleep. This common symptom is distinct from weakness, which involves the muscles, but may accompany it.
Fatigue is a normal and important response to physical... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Patient counseling
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... Resulting from severe constriction of the visual field that leaves only a small central area of sight, tunnel vision is typically described as the sensation of looking through a tunnel or gun barrel. It may be unilateral or bilateral and usually... History and physical examination ... Medical causes ... Special considerations ... Pediatric pointers ... Patient counseling ... Pictures
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... S. Shekar Chakravarthi
Anemia is defined as a reduction of more than 10% below mean values in the quantity or quality of the concentration of red blood cells (RBC) or circulating hemoglobin. In 1972, the World Health Organization... Pictures
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... Meg Hayes
Fatigue is both a normal human response as well as a symptom of physical or psychological disease. It is a subjective sensation that is multicausal and nonspecific for which no one definition is universally accepted, nor can it... Approach ... History ... Physical examination ... Testing. ... Diagnostic assessment
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... Differential Overview
❑ Iron deficiency
❑ Chronic disease
❑ Vitamin B12 deficiency
❑ Subacute blood loss ... Diagnostic Approach ... Clinical Findings
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... Differential Overview
❑ Infectious mononucleosis
❑ Depression
❑ Diabetes
❑ Hypothyroidism
... Diagnostic Approach ... Clinical Findings
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... A syndrome of persistent dehydration, hyperchloremia, hypokalemia, metabolic acidosis, and nephrocalcinosis, renal tubular acidosis (RTA) results from the kidneys’inability to conserve bicarbonate. This disorder occurs as distal RTA (type I, or classic RTA) or proximal... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Aplastic and hypoplastic anemias result from injury to or destruction of stem cells in bone marrow or the bone marrow matrix, causing pancytopenia (anemia, granulocytopenia, thrombocytopenia) and bone marrow hypoplasia. Although often used interchangeably with other terms for bone... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Chronic fatigue and immune dysfunction syndrome (CFIDS) — also known as chronic fatigue syndrome, chronic Epstein-Barr virus [EBV], benign myalgic encephalomyelitis, and “Yuppie flu” — is typically marked by debilitating fatigue,... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... A common, slowly progressive megaloblastic anemia, folic acid deficiency anemia is most prevalent in infants, adolescents, pregnant and lactating females, alcoholics, elderly people, and people with malignant or intestinal diseases.
Causes
... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... With iron deficiency anemia, an inadequate supply of iron for optimal formation of red blood cells (RBCs) results in smaller (microcytic) cells with less color on staining. Body stores of iron, including plasma iron, decrease, as does transferrin, which binds with and transports iron.... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Prevention ... Pictures
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... A megaloblastic anemia, pernicious anemia (also called Addison’s anemia) is characterized by decreased gastric production of hydrochloric acid and deficiency of intrinsic factor (IF), a substance normally secreted by the parietal cells of the gastric... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
... READ EXCERPTS »
... A congenital hemolytic anemia that occurs primarily, but not exclusively, in blacks, sickle cell anemia results from a defective hemoglobin (Hb) molecule (Hb S) that causes red blood cells (RBCs) to roughen and become sickle shaped. Such cells impair circulation, resulting in chronic ill... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
... READ EXCERPTS »
... Sideroblastic anemias, a group of heterogenous disorders, produce a common defect — failure to use iron in hemoglobin (Hb) synthesis, despite the availability of adequate iron stores. These anemias may be hereditary or acquired; the acquired... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Fatigue is a feeling of excessive tiredness, lack of energy, or exhaustion accompanied by a strong desire to rest or sleep. This common symptom is distinct from weakness, which involves the muscles, but may occur with it.
Fatigue... History ... Physical assessment ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Patient counseling ... Pictures
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...Defined as lack of energy for activitiesand decreased endurance for them. Principal Causes of Fatigue Physiologiccauses Pathologic causes Anemia Infection Chronic disease Allergic disease Chronic fatigue ... Clinical Features and Diagnosis ... Diagnostic Approach ... References
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... A decreasein blood Hgb concentration or Hct (a measure of red cell mass) thatis 2 standard deviations below mean for age and gender is definedas anemia. Pallor as sign of anemia depends onconcentration of Hgb in blood. When Hgb... Principal Causes of Pallor (Anemia) ... Clinical Features and Diagnosis ... Table 45.1. Hemoglobin Electrophoretic Patterns of Common Hemoglobinopathiesin Cord and Adult Blood ... Diagnostic Approach ... Table 45.2. Morphologic Classification of Anemia Based on Red CellMean Corpuscular Volume ... Table 45.3. Abnormal Blood Smear Findings and Possible Causes ... References
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... Fatigue is a feeling of excessive tiredness, a lack of energy, or exhaustion accompanied by a strong desire to rest or sleep. This common symptom is distinct from weakness, which involves the muscles, but may occur with it.
Fatigue... History and physical examination ... Medical causes ... Other causes ... Nursing considerations ... Patient teaching ... Pictures
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... Resulting from severe constriction of the visual field that leaves only a small central area of sight, tunnel vision is typically described as the sensation of looking through a tunnel or gun barrel. It may be unilateral or bilateral and usually develops gradually. (See ... History and physical examination ... Medical causes ... Nursing considerations ... Patient teaching ... Pictures
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In developing a list of diagnostic possibilities in cases of anemia,
physiology is the key. Anemia may be caused by a decrease in red cell
production, a break in the transport system (blood loss), or excessive red
cell destruction.
...
The analysis of the causes of weakness depends on a knowledge of both
anatomy and biochemistry. Strength depends on an intact
healthy muscle, peripheral nerve, and lower and upper motor neuron pathways
and a... Pictures
... READ EXCERPTS »
...
Developing a list of possible causes of acidosis is also best
approached by using the physiologic model of production, transport,
excretion, or degradation.
Production Acids... Pictures
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... Author:
Heidi Herrera, MD
What to Do - Make a Decision
Anemia can present in children who are otherwise healthy, or who have
systemic disease or a known hematologic disorder. Anemia is defined as a
reduction in... Suggested Readings
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... Janet L. Kwiatkowski, MD Aplastic Anemia - BASICS Aplastic Anemia - description A heterogeneous disorder within the bone marrow failure syndromes Characterized by a marked decrease ... Aplastic Anemia - DIAGNOSIS ... Aplastic Anemia - TREATMENT ... Aplastic Anemia - FOLLOW UP ... Aplastic Anemia - bibliography ... Aplastic Anemia - CODES ... Aplastic Anemia - FAQ
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... Andres J. Greco, MD Renal Tubular Acidosis - BASICS Renal Tubular Acidosis - description Group of transport defects produced by a failure to reabsorb filtered bicarbonate (type II), or an ... Renal Tubular Acidosis - DIAGNOSIS ... Renal Tubular Acidosis - TREATMENT ... Renal Tubular Acidosis - FOLLOW UP ... Renal Tubular Acidosis - bibliography ... Renal Tubular Acidosis - CODES
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For most breast cancer patients, adjuvant therapy is a crucial part of treatment. Like many successful drug therapies, however, adjuvant therapy can...
There have been many advances in improving the outcome of people living with cancer. Although, many people are living longer with their disease,...
Heart failure affects approximately 5 million people in the United States. It can be caused by a number of conditions and treatment options may vary...