PEDIATRIC TIP In children younger than age 2, fever, vomiting, nonspecific abdominal complaints, or failure to thrive may be the only signs of acute pyelonephritis.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Kidney cancer:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Kidney cancer produces a classic clinical triad (hematuria, pain, and a palpable mass), but any one may be the first sign of cancer. Microscopic or gross hematuria (which may be intermittent) suggests that the cancer has spread to the renal pelvis. Constant abdominal or flank pain may be dull or, if the cancer causes bleeding or blood clots, acute and colicky. The mass is generally smooth, firm, and nontender. All three signs coexist in only about 10% of patients.
Other signs include fever (perhaps from hemorrhage or necrosis), hypertension (from compression of the renal artery with renal parenchymal ischemia), rapidly progressing hypercalcemia (possibly from ectopic parathyroid hormone production by the tumor), and urine retention. Weight loss, edema in the legs, nausea, and vomiting signal advanced disease.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Medullary sponge kidney:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Symptoms usually appear only as a result of complications and are seldom present before adulthood. Complications include formation of calcium oxylate stones, which lodge in the dilated cystic collecting ducts or pass through a ureter, and infection secondary to dilation of the ducts. These complications, which occur in about 30% of patients, are likely to produce severe colic, hematuria, lower urinary tract infection ([UTI]; burning on urination, urgency, frequency), and pyelonephritis. Secondary impairment of renal function from obstruction and infection occurs in only about 10% of patients.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Polycystic kidney disease:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
The neonate with infantile polycystic disease often has pronounced epicanthal folds, a pointed nose, a small chin, and floppy, low-set ears (Potter facies). At birth, he has huge bilateral masses on the flanks that are symmetrical, tense, and can’t be transilluminated. He characteristically shows signs of respiratory distress and heart failure. Eventually, he develops uremia and renal failure. Accompanying hepatic fibrosis may cause portal hypertension and bleeding varices to develop, requiring sclerotherapy or portacaval shunting.
Adult polycystic kidney disease is commonly asymptomatic through the patient’s 40s, but may induce nonspecific symptoms, such as hypertension, polyuria, and recurrent urinary tract infections (UTIs). Later, the patient develops overt symptoms related to the enlarging kidney mass, such as lumbar pain, widening girth, and swollen or tender abdomen. Abdominal pain is usually worsened by exertion and relieved by lying down. In advanced stages, this disease may cause recurrent hematuria, life-threatening retroperitoneal bleeding resulting from cyst rupture, proteinuria, and colicky abdominal pain from the ureteral passage of clots or calculi. Generally, about 10 years after symptoms appear, progressive compression of kidney structures by the enlarging mass produces renal failure and uremia. Hypertension is found in about 20% to 30% of children and up to 75% of adults due to intrarenal ischemia, which activates the renin-angiotensin system.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Pyelonephritis, acute:
Signs and symptoms
(Handbook of Diseases)
Typical clinical features include urgency, frequency, burning during urination, dysuria, nocturia, and hematuria (usually microscopic but may be gross). Urine may appear cloudy and have an ammoniacal or fishy odor. Other common symptoms include a temperature of 102° F (38.9° C) or higher, shaking chills, flank pain, anorexia, and general fatigue.
These signs and symptoms characteristically develop rapidly over a few hours or a few days. Although these symptoms may disappear within days, even without treatment, residual bacterial infection is likely and may cause later recurrence of symptoms.
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Source: Handbook of Diseases, 2003
Kidney cancer:
Signs and symptoms
(Handbook of Diseases)
Kidney cancer produces a classic triad of signs and symptoms — hematuria, pain, and a palpable mass — but any one may be the first indication of cancer. Microscopic or gross hematuria (which may be intermittent) suggests that the cancer has spread to the renal pelvis.
Constant abdominal or flank pain may be dull or, if the cancer causes bleeding or blood clots, acute and colicky. The mass is generally smooth, firm, and nontender. All three signs of kidney cancer coexist in only about 10% of patients.
Other signs and symptoms include fever (perhaps from hemorrhage or necrosis), hypertension (from compression of the renal artery with renal parenchymal ischemia), rapidly progressing hypercalcemia (possibly from ectopic parathyroid hormone production by the tumor), and urine retention. Weight loss, edema in the legs, nausea, and vomiting are signs and symptoms of advanced kidney cancer.
CLINICAL TIP: Bone pain or fracture from a metastatic lesion may also be a chief complaint.
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Source: Handbook of Diseases, 2003
Polycystic kidney disease:
Signs and symptoms
(Handbook of Diseases)
Clinical features vary with the form of disease.
Infantile form
The neonate with infantile polycystic disease may have pronounced epicanthal folds, a pointed nose, a small chin, and floppy, low-set ears (Potter facies). Signs of respiratory distress and heart failure may be evident. Eventually, he develops uremia and renal failure. Accompanying hepatic fibrosis may cause the development of portal hypertension and bleeding varices.
Adult form
Adult polycystic kidney disease is commonly asymptomatic while the patient is in his thirties and forties but may induce nonspecific signs and symptoms, such as hypertension, polyuria, and urinary tract infection. Later, the patient develops overt signs and symptoms related to the enlarging kidney mass, such as lumbar pain, widening girth, and a swollen or tender abdomen. Such abdominal pain is usually worsened by exertion and relieved by lying down.
In advanced stages, this disease may cause recurrent hematuria, life-threatening retroperitoneal bleeding resulting from a ruptured cyst, proteinuria, and colicky abdominal pain from the ureteral passage of clots or calculi. Generally, about 10 years after symptoms appear, progressive compression of kidney structures by the enlarging mass produces renal failure and uremia.
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Source: Handbook of Diseases, 2003
Pyelonephritis:
Pyelonephritis - signs & symptoms
(The 5-Minute Pediatric Consult)
- Fever
- Chills
- Flank pain
- Urination problems: Dysuria, frequency, urgency
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Source: The 5-Minute Pediatric Consult, 2008
Article Excerpts About Symptoms of Pyelonephritis:
Symptoms and signs include back, side, and groin pain; urgent, frequent
urination; pain or burning during urination; fever; nausea and vomiting;
and pus and blood in the urine.
(Source: excerpt from Pyelonephritis (Kidney Infection) in Adults: NIDDK)
Pyelonephritis as a symptom:
For a more detailed analysis of Pyelonephritis as a symptom, including causes, drug side effect causes, and drug interaction causes, please see our Symptom Center information for Pyelonephritis.
Medical articles and books on symptoms:
These general reference articles may be of interest
in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
About signs and symptoms of Pyelonephritis:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Pyelonephritis.
This signs and symptoms information for Pyelonephritis has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Pyelonephritis signs or Pyelonephritis symptoms.
Furthermore, signs and symptoms of Pyelonephritis may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Pyelonephritis symptoms.
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