Diseases » Resistance to thyroid stimulating hormone

Serum Thyroid-Stimulating Hormone

Serum Thyroid-Stimulating Hormone: Excerpt from A Pocket Manual of Differential Diagnosis

Elevated Serum Thyroid-Stimulating Hormone

Primary hypothyroidism
Overt (low free T₄)
Subclinical (normal free T₄)
Assay problems
   Assay variability
   Heterophile antibodies interfering with the TSH assay
Drugs
   Domperidone
   Metoclopramide
Pulsatile TSH secretion, nocturnal TSH surge
Recovery from nonthyroidal illness
Thyroid hormone resistance syndromes
TSH-secreting pituitary tumors

Suppressed Serum Thyroid-Stimulating Hormone

Thyrotoxicosis
Overt (low free T₄)
Subclinical (normal free T₄)
T₃ Toxicosis (with normal or low free T₄)
After treatment of thyrotoxicosis, before the axis recovers from suppression
Drugs
   Dopamine
   Glucocorticoids
Laboratory error
Secondary (pituitary) and tertiary (hypothalamic) hypothyroidism
Severe nonthyroidal illness

References

1. Ross DS: Subclinical Hypothyroidism, pp. 1010–1011. See Bibliography, 4.
2. Ross DS: Subclinical Thyrotoxicosis, pp. 1016–1017. See Bibliography, 4.

Book Source Details

• Book Title: A Pocket Manual of Differential Diagnosis
• Author(s): Stephen N. Adler, Dianne B. Gasbarra
• Year of Publication: 1999
• Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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More About This Book: Title: A Pocket Manual of Differential Diagnosis Authors: Stephen N. Adler, Dianne B. Gasbarra Publisher: Lippincott Williams & Wilkins Copyright: 1999 ISBN: 0-78171-943-7

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