Prevalence and Incidence of Retinoblastoma

Prevalance of Retinoblastoma:

3% of cancers in children under the age of 15 are due to retinoblastomas, Genetics Home Reference website ... see also overview of Retinoblastoma.

Prevalance Rate:

approx 1 in 33 or 3.00% or 8.2 million people in USA [Source statistic for calcuation: "3% of cancers in children under the age of 15 are due to retinoblastomas, Genetics Home Reference website" -- see also general information about data sources]

Retinoblastoma: Rare Disease

Retinoblastoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Retinoblastoma, or a subtype of Retinoblastoma, affects less than 200,000 people in the US population.

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Retinoblastoma as a "rare disease". More information about Retinoblastoma is available from Orphanet

Retinoblastoma Prevalence: Book Excerpts

• Causes and incidence - Malignant spinal neoplasms
• Neuroblastoma - epidemiology - Neuroblastoma
• Retinoblastoma - epidemiology - Retinoblastoma

Incidence (annual) of Retinoblastoma:

estimated 1 per 250 children are diagnosed with retinoblastomas each year, Genetics Home Reference website ... see also overview of Retinoblastoma.

Incidence Rate:

approx 1 in 249 or 0.40% or 1.1 million people in USA [Source statistic for calcuation: "estimated 1 per 250 children are diagnosed with retinoblastomas each year, Genetics Home Reference website" -- see also general information about data sources]

Incidence extrapolations for USA for Retinoblastoma:

1,088,000 per year, 90,666 per month, 20,923 per week, 2,980 per day, 124 per hour, 2 per minute, 0 per second. [Source statistic for calculation: "estimated 1 per 250 children are diagnosed with retinoblastomas each year, Genetics Home Reference website" -- see also general information about data sources]

Prevalance of Retinoblastoma:

Retinoblastoma occurs in early childhood and affects about 1 child in 20,000. (Source: Genes and Disease by the National Center for Biotechnology)

Prevalence/Incidence of Retinoblastoma: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Retinoblastoma.

Malignant spinal neoplasms: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

Primary tumors of the spinal cord may be extramedullary (occurring outside the spinal cord) or intramedullary (occurring within the cord itself). Extramedullary tumors may be intradural (meningiomas and schwannomas), which account for 60% of all primary malignant spinal cord neoplasms, or extradural (metastatic tumors from breasts, lungs, prostate, leukemia, or lymphomas), which account for 25% of these malignant neoplasms.

Intramedullary tumors, or gliomas (astrocytomas or ependymomas), are comparatively rare, accounting for only about 10%. In children, they're low-grade astrocytomas.

Spinal cord tumors are rare compared with intracranial tumors (ratio of 1:4). They occur equally in men and women, with the exception of meningiomas, which occur mostly in women. Spinal cord tumors can occur anywhere along the length of the cord or its roots.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Neuroblastoma: Neuroblastoma - epidemiology
(The 5-Minute Pediatric Consult)

• Most children are <5 years of age at diagnosis.
• ~50% of children have disseminated disease at diagnosis.
• Male/Female ratio 1.1:1
• More common in whites
• Most primary tumors are in the abdomen.

Neuroblastoma - prevalence

Neuroblastoma accounts for ~7–10% of all childhood cancers.

Neuroblastoma - incidence

About 800 new cases per year in the US (10 per million children per year)

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

Retinoblastoma: Retinoblastoma - epidemiology
(The 5-Minute Pediatric Consult)

• 1:16,000–25,000 live births
• The most common primary intraocular tumor of childhood (ocular leukemia most common overall)
• Represents 3% of all pediatric malignancies
• No sex, race, geographic, or socioeconomic predilection
• 90% diagnosed <4 years of age
• Median age at diagnosis for unilateral disease is 24 months and 12 months for bilateral disease (see “Genetics”)

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Retinoblastoma usually refers to the estimated population of people who are managing Retinoblastoma at any given time. The term 'incidence' of Retinoblastoma refers to the annual diagnosis rate, or the number of new cases of Retinoblastoma diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

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