Prevalence and Incidence of Rett's syndrome
Prevalance of Rett's syndrome:
estimated 1 per 10,000 - 22,000 females suffer from Rett syndrome, Genetics Home Reference website ... see also overview of Rett's syndrome.
Prevalance Rate:
approx 1 in 10,000 or 0.01% or 27,200 people in USA [Source statistic for calcuation: "estimated 1 per 10,000 - 22,000 females suffer from Rett syndrome, Genetics Home Reference website" -- see also general information about data sources]
Rett's syndrome: Rare Disease
Rett's syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Rett's syndrome, or a subtype of Rett's syndrome,
affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Rett's syndrome as a "rare disease".
More information about Rett's syndrome is available from Orphanet
Rett's syndrome Prevalence: Book Excerpts
Incidence (annual) of Rett's syndrome:
1 in 10,000-15,000 live female births ... see also overview of Rett's syndrome.
Incidence Rate:
approx 1 in 10,000 or 0.01% or 27,200 people in USA [Source statistic for calcuation: "1 in 10,000-15,000 live female births" -- see also general information about data sources]
Incidence extrapolations for USA for Rett's syndrome:
27,199 per year,
2,266 per month,
523 per week,
74 per day,
3 per hour,
0 per minute,
0 per second.
[Source statistic for calculation: "1 in 10,000-15,000 live female births" -- see also general information about data sources]
Prevalance of Rett's syndrome:
The syndrome affects
approximately 1 in every 10,000-15,000 live female births, with symptoms
usually appearing in early childhood — between ages 6 and 18 months.
(Source: excerpt from NINDS Rett Syndrome Information Page: NINDS)
More Statistics about Rett's syndrome:
Hospitalization statistics
All statistics for Rett's syndrome
Prevalence/Incidence of Rett's syndrome: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Rett's syndrome.
Autistic disorder:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
The causes of autistic disorder remain unclear but are thought to include psychological, physiologic, and sociological factors. Much evidence has accumulated to suggest a biological substrate. The parents of a child who’s autistic may appear distant and unaffectionate. However, because children who are autistic are unresponsive or respond with rigid, screaming resistance to touch and attention, parental remoteness may be merely a frustrated, helpless reaction to this disorder, not its cause.
Some children who are autistic show abnormal but nonspecific EEG findings that suggest brain dysfunction, possibly resulting from trauma, disease, or a structural abnormality. Autistic disorder has also been associated with maternal rubella, untreated phenylketonuria, tuberous sclerosis, anoxia during birth, encephalitis, infantile spasms, and fragile X syndrome. Studies have established a link with abnormalities in neurotransmitters, including (in some cases) increased dopamine and increased serotonin. There appears to be a genetic component as well; between 2% and 4% of siblings of those with autism also had autistic disorders at a rate higher than the general population.
Autistic disorder is rare, affecting 4 to 5 children per 10,000 births. It affects three to four times more boys than girls.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Ataxia:
Ataxia - epidemiology
(The 5-Minute Pediatric Consult)
Ataxia - incidence
- ~1 in 1,000 children develop acute ataxia following varicella infection.
- The most common congenital cerebellar syndromes are caused by perinatal trauma and hypercoagulable or hemorrhagic vascular events (“ataxic cerebral palsy”). Fetal stroke is estimated to complicate 1 in 4,000 full-term births. The Dandy-Walker syndrome and structural cerebellar abnormalities are rarer causes of congenital cerebellar dysfunction.
- Metabolic/heredodegenerative causes are rare.
- Friedreich ataxia incidence is 2–4 in 100,000.
- Ataxia with oculomotor apraxia occurrence is near 5 in 100,000.
Ataxia - prevalence
Cerebellar medulloblastomas represent 20% of pediatric primary brain tumors (associated with (ataxia-telangiectasia, basal cell nevus syndrome). Cerebellar astrocytomas, fourth ventricle ependymomas, and brainstem gliomas are also more common in children than in adults.
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Rett's syndrome usually refers to the estimated population
of people who are managing Rett's syndrome at any given time.
The term 'incidence' of Rett's syndrome refers to the annual diagnosis rate,
or the number of new cases of Rett's syndrome diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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