SCID

SCID: Introduction

SCID: Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining feature ... more about SCID.

SCID: Major failure of the immune system, usually genetic. More detailed information about the symptoms, causes, and treatments of SCID is available below.

Symptoms of SCID

• Recurrent infections - often serious and life-threatening
• Pneumonia
• Meningitis
• Sepsis
• Chickenpox
• more symptoms...»

See full list of 37 symptoms of SCID

Home Diagnostic Testing

Home medical testing related to SCID:

• Home STD Testing
  • Home HIV Tests
  • Home Chlamydia Tests
  • Home Hepatitis Tests
  • Home Herpes Tests
  • Home Trichomonas Tests
• Sexuality & Libido: Home Testing:
  • Home Hormone Tests
  • Home Libido Tests
  • Home Menopause Testing
  • Home Andropause Tests
• Liver Health & Hepatitis: Home Testing
  • Home Hepatitis Tests
  • Home Liver Tests
  • Sexually Transmitted Disease Tests
• more tests...»

SCID: Complications

Review possible medical complications related to SCID:

• Death due to infection
• more complications...»

Medical Textbooks Online about SCID

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Less Common Symptoms of SCID

• Reduced white blood cell count
• Lack of granulocytes
• more symptoms...»

Read more about symptoms of SCID

Diagnostic Tests for SCID

• Immune function blood tests
• B-cell levels
• T-cell levels
• IgG levels
• IgA levels
• more tests...»

See full list of 6 diagnostic tests for SCID

Wrongly Diagnosed with SCID?

• Misdiagnosis of SCID
• Failure to diagnose SCID
• Undiagnosed: SCID

SCID: Medical Mistakes

• STDs -- Health Mistakes
• more mistakes...»

SCID: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for SCID:

• Sexual Health
• more product offers...»

SCID: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

• Sexual Disorders & STDs -- serious diseases often undiagnosed:
  • Sexually Transmitted Diseases -- Undiagnosed
  • Chlamydia -- Undiagnosed
  • Gonorrhea -- Undiagnosed
  • HIV -- Undiagnosed
  • Genital Herpes -- Undiagnosed
  • Hepatitis -- Undiagnosed
  • more ...»
• more undiagnosed conditions...»

SCID: Research Doctors & Specialists

Research related physicians and medical specialists:

• Immune-Related Disease Specialists (Immunology):
  • Allergy & Immunology (Allergies & Immune Diseases)
  • Pediatric Allergy and Immunology (Child Allergies & Immune Diseases)
  • Immunopathology
  • Dermatological Immunology / Diagnostic Laboratory
  • Clinical & Laboratory Immunology
• more specialists...»

Other doctor, physician and specialist research services:

• Rate Your Doctor Online
• Research Your Doctor Online
• Review Patient Surveys About Your Doctor
• Research local specialists including ratings, affiliations, and sanctions.

Hospitals & Clinics: SCID

Research quality ratings and patient safety measures for medical facilities in specialties related to SCID:

• Urinary Health (Urology) -- Hospital Quality Ratings
• more hospital ratings...»

Hospital & Clinic quality ratings » »

Choosing the Best Hospital: More general information, not necessarily in relation to SCID, on hospital performance and surgical care quality:

• 50 Best Hospitals Report
• Outstanding Patient Experinece Award Winning Hospitals
• Women's Health Best Hospitals
• Patient Safety
• Hospital Quality and Clinical Excellence Study (2009)

Causes of SCID

• Omenn syndrome
• X-linked severe combined immunodeficiency
• Reticular dysgenesis
• Bare lymphocyte syndrome type 2
• Leukocyte-common antigen deficiency
• more causes...»

See full list of 6 causes of SCID

Read more about causes of SCID.

Treatments for SCID

• Bone marrow transplant
• Intravenous immunoglobulin (IVIG)
• PEG-ADA injections - for ADA deficiency subtype.
• more treatments...»

Read more about treatments for SCID

News Archives for SCID

Medical news articles related to SCID include:

• Tailored Treatments Effective for Depression Due to Pain
• Gene Gives Clues to Why Autism More Common in Boys
• Plavix, Heartburn Drugs May Be Risky Combination
• Early Psychiatric Issues May Predict Suicide in Boys
• More Teen Boys Are Using Smokeless Tobacco, Survey Finds
• Drug Combinations Putting Seniors at Risk
• more health news...»

Source: HealthDay News

Videos for SCID

Patient Surveys for SCID

• Patient Profile Survey
  Take Survey  View Results
• Survey about the symptoms of your SCID
  Take Survey  View Results

Reseach about SCID

Visit our research pages for current research about SCID treatments.

Clinical Trials for SCID

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for SCID include:

• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies - This study is no longer recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,busulfan,cyclophosphamide,cyclosporine,etoposide,methotrexate,methylprednisolone,prednisone
• Pilot Study of Allogeneic Bone Marrow Transplantation Plus Cyclosporine and Mycophenolate Mofetil to Induce Mixed Hematopoietic Chimerism in Patients With Primary T-Cell Immunodeficiency Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - cyclosporine,mycophenolate mofetil
• Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Filgrastim,Alemtuzumab
• Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study - This study has been completed (Current: 23 Nov 2006) - ADA PBSC,ADA Umbilical Cord Blood Cells,Transduced Lymphocytes
• Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency - This study is currently recruiting patients (Current: 23 Nov 2006) - BB-IND 8556
• more trials...»

See full list of 14 Clinical Trials for SCID

Statistics for SCID

• Medical statistics for SCID
• Prevalence and incidence statistics for SCID
• Death and Mortality statistics for SCID
• Society statistics for SCID

SCID: Broader Related Topics

• Primary Immune Deficiency
• Immune disorders
• Immune deficiency conditions
• more types...»

Types of SCID

Types of SCID

• SCID with ADA deficiency - X-linked common type
• SCID from IL-2 receptor gamma chain deficiency - X-linked common type
• X-linked SCID
• MHC Class II Deficiency (Bare Lymphocyte Syndrome)
• DiGeorge syndrome
• more types...»

See full list of 6 Types of SCID

Stories from Users Related to SCID

• My 4 yr old little boy... please help
• weird combination of symptoms. is this right?
• Hair loss due to medication
• Teenage boy needs help
• Massive Weight Loss due to Nausea
• Weirdest combination of Symptoms, Need a diagnosis!!!
• Immune Deficiency???
• 3 and a half year boy
• Gas bubbles in esophagus or what?!
• combined symptoms and no diagnosis
• 8 month old baby boy nees help
• desperate! Combination of symptoms! please help!
• Help, Infection, Autoimmunity, Immune Deficiency
• Combination of pain - HELP
• 6YRS OLD BOY WITH - BRAIN - neurological illness
• Hair Loss... at 19 !! maybe due to bad habits
• Divorce due to ears
• Extra Large Hives due to stress
• Depressive disorder due to gerascophobia?
• Esophegeal Stricture due to caustic burns

Related forums and medical stories:

• Immune Conditions (46)
  • IGA Deficiency
  • hypogammaglobulinemia-2nd opinions
  • Never ending cough
  • Cvid
  • Diarrhea and gas problems possibly related with my IgA deficiency?
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about SCID, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about SCID

Genes and Disease by the National Center for Biotechnology (Excerpt)

Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining feature of SCID, commonly known as "bubble boy" disease, is a defect in the specialized white blood cells (B- and T-lymphocytes) that defend us from infection by viruses, bacteria and fungi. (Source: Genes and Disease by the National Center for Biotechnology)

Primary Immune Deficiency, NIAID Fact Sheet: NIAID (Excerpt)

Approximately one in every million people develop SCID, a group of inherited disorders. People with SCID have severe abnormalities in both B and T cell immunity. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Definitions of SCID:

X-linked or autosomal recessive disorder characterized by defects of both humoral and cell mediated immunity, resulting in low or absent antibody levels, leukopenia, marked susceptibility to infections, and early death.--2004 - (Source - Diseases Database)

A congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life - (Source - WordNet 2.1)

SCID is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that SCID, or a subtype of SCID, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)