What is Scleroderma?
What is Scleroderma?
- Scleroderma: A rare, progressive connective tissue disorder involving thickening and hardening of the skin and connective tissue. There are a number of forms of scleroderma with some forms being systemic (involving internal organs).
- Scleroderma: systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibrotic degenerative changes in various body organs including the heart, lungs, kidneys, and gastrointestinal tract.
Source - Diseases Database
- Scleroderma: an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin.
Source - WordNet 2.1
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Scleroderma as a "rare disease".
Source - Orphanet
Scleroderma: Introduction
Types of Scleroderma:
Types of Scleroderma:
Broader types of Scleroderma:
How many people get Scleroderma?
Prevalance of Scleroderma: estimated 300,000 Americans (NWHIC)
Prevalance Rate of Scleroderma: approx 1 in 906 or 0.11% or 300,000 people in USA [about data]
Prevalance of Scleroderma:
Estimates for the number of people in
the United States with systemic sclerosis range from 40,000 to 165,000.
By contrast, a survey that included all scleroderma-related disorders,
including Raynaud's phenomenon, suggested a number between 250,000 and
992,500. (Source: excerpt from Handout on Health Scleroderma: NIAMS)
...
The
estimated number of people with any type of scleroderma varies from study to
study but may range from 1 to 4 affected individuals for every 10,000 Americans
(or as many as 1 out of 2500 individuals). (Source: excerpt from Understanding Autoimmune Disease: NIAID)
Who gets Scleroderma?
Patient Profile for Scleroderma: Mostly in middle age
Profile for Scleroderma: Although scleroderma is more common in women, the disease
also occurs in men and children. It affects people of all races and
ethnic groups. (Source: excerpt from Handout on Health Scleroderma: NIAMS)
Gender Profile for Scleroderma: About 80% women (NWHIC). More common in women. Women 3:1 men.
How serious is Scleroderma?
Complications of Scleroderma:
see complications of Scleroderma
Prognosis of Scleroderma: For some people, scleroderma (particularly the localized
forms) is fairly mild and resolves with time. But for others, living
with the disease and its effects day to day has a significant impact on
their quality of life. (Source: excerpt from Handout on Health Scleroderma: NIAMS)
...
No cure
exists, but timely intervention can improve the quality of
life. (Source: excerpt from Connective Tissue Diseases: NWHIC)
What causes Scleroderma?
Causes of Scleroderma: see causes of Scleroderma
Cause of Scleroderma: Probably autoimmune. Not contagious. Not genetic.
Risk factors for Scleroderma:
see
risk factors for Scleroderma
What are the symptoms of Scleroderma?
Symptoms of Scleroderma:
see symptoms of Scleroderma
Complications of Scleroderma:
see complications of Scleroderma
Can anyone else get Scleroderma?
Contagion of autoimmunity:
generally not; see details in contagion of autoimmune diseases.
Inheritance:
see inheritance of Scleroderma
Scleroderma: Testing
Diagnostic testing: see tests for Scleroderma.
Misdiagnosis: see misdiagnosis and Scleroderma.
How is it treated?
Treatments for Scleroderma:
see treatments for Scleroderma
Research for Scleroderma:
see research for Scleroderma
Society issues for Scleroderma
Hospitalization statistics for Scleroderma:
The following are statistics from various sources about hospitalizations and Scleroderma:
- 0.018% (2,281) of hospital consultant episodes were for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 92% of hospital consultant episodes for systemic sclerosis required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 18% of hospital consultant episodes for systemic sclerosis were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 82% of hospital consultant episodes for systemic sclerosis were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 14% of hospital consultant episodes for systemic sclerosis required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 10 days was the mean length of stay in hospitals for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 5 days was the median length of stay in hospitals for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more statistics...»
Organs Affected by Scleroderma:
Organs and body systems related to Scleroderma include:
Name and Aliases of Scleroderma
Main name of condition: Scleroderma
Class of Condition for Scleroderma: autoimmune
Other names or spellings for Scleroderma:
Systemic Sclerosis, Progressive Systemic Sclerosis, PSS
Systemic sclerosis
Source - Diseases Database
Dermatosclerosis
Source - WordNet 2.1
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