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Diseases » Scleroderma » Summary
 

What is Scleroderma?

What is Scleroderma?

  • Scleroderma: A rare, progressive connective tissue disorder involving thickening and hardening of the skin and connective tissue. There are a number of forms of scleroderma with some forms being systemic (involving internal organs).
  • Scleroderma: systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibrotic degenerative changes in various body organs including the heart, lungs, kidneys, and gastrointestinal tract.
    Source - Diseases Database
  • Scleroderma: an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin.
    Source - WordNet 2.1

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Scleroderma as a "rare disease".
Source - Orphanet

Scleroderma: Introduction

Types of Scleroderma:

Types of Scleroderma:

Broader types of Scleroderma:

How many people get Scleroderma?

Prevalance of Scleroderma: estimated 300,000 Americans (NWHIC)
Prevalance Rate of Scleroderma: approx 1 in 906 or 0.11% or 300,000 people in USA [about data]
Prevalance of Scleroderma: Estimates for the number of people in the United States with systemic sclerosis range from 40,000 to 165,000. By contrast, a survey that included all scleroderma-related disorders, including Raynaud's phenomenon, suggested a number between 250,000 and 992,500. (Source: excerpt from Handout on Health Scleroderma: NIAMS) ... The estimated number of people with any type of scleroderma varies from study to study but may range from 1 to 4 affected individuals for every 10,000 Americans (or as many as 1 out of 2500 individuals). (Source: excerpt from Understanding Autoimmune Disease: NIAID)

Who gets Scleroderma?

Patient Profile for Scleroderma: Mostly in middle age

Profile for Scleroderma: Although scleroderma is more common in women, the disease also occurs in men and children. It affects people of all races and ethnic groups. (Source: excerpt from Handout on Health Scleroderma: NIAMS)

Gender Profile for Scleroderma: About 80% women (NWHIC). More common in women. Women 3:1 men.

How serious is Scleroderma?

Complications of Scleroderma: see complications of Scleroderma
Prognosis of Scleroderma: For some people, scleroderma (particularly the localized forms) is fairly mild and resolves with time. But for others, living with the disease and its effects day to day has a significant impact on their quality of life. (Source: excerpt from Handout on Health Scleroderma: NIAMS) ... No cure exists, but timely intervention can improve the quality of life. (Source: excerpt from Connective Tissue Diseases: NWHIC)

What causes Scleroderma?

Causes of Scleroderma: see causes of Scleroderma
Cause of Scleroderma: Probably autoimmune. Not contagious. Not genetic.
Risk factors for Scleroderma: see risk factors for Scleroderma

What are the symptoms of Scleroderma?

Symptoms of Scleroderma: see symptoms of Scleroderma

Complications of Scleroderma: see complications of Scleroderma

Can anyone else get Scleroderma?

Contagion of autoimmunity: generally not; see details in contagion of autoimmune diseases.
Inheritance: see inheritance of Scleroderma

Scleroderma: Testing

Diagnostic testing: see tests for Scleroderma.

Misdiagnosis: see misdiagnosis and Scleroderma.

How is it treated?

Treatments for Scleroderma: see treatments for Scleroderma
Research for Scleroderma: see research for Scleroderma

Society issues for Scleroderma


Hospitalization statistics for Scleroderma: The following are statistics from various sources about hospitalizations and Scleroderma:

  • 0.018% (2,281) of hospital consultant episodes were for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 92% of hospital consultant episodes for systemic sclerosis required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 18% of hospital consultant episodes for systemic sclerosis were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 82% of hospital consultant episodes for systemic sclerosis were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 14% of hospital consultant episodes for systemic sclerosis required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 10 days was the mean length of stay in hospitals for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 5 days was the median length of stay in hospitals for systemic sclerosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more statistics...»

Organs Affected by Scleroderma:

Organs and body systems related to Scleroderma include:

Name and Aliases of Scleroderma

Main name of condition: Scleroderma

Class of Condition for Scleroderma: autoimmune

Other names or spellings for Scleroderma:

Systemic Sclerosis, Progressive Systemic Sclerosis, PSS

Systemic sclerosis Source - Diseases Database

Dermatosclerosis
Source - WordNet 2.1

Research the causes of these diseases that are similar to, or related to, Scleroderma:


 » Next page: Online Medical Textbooks for Scleroderma

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