estimated 300,000 Americans (NWHIC) ... see also overview of Scleroderma.
approx 1 in 906 or 0.11% or 300,000 people in USA [Source statistic for calcuation: "estimated 300,000 Americans (NWHIC)" -- see also general information about data sources]
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Scleroderma as a "rare disease". More information about Scleroderma is available from Orphanet
Estimates for the number of people in the United States with systemic sclerosis range from 40,000 to 165,000. By contrast, a survey that included all scleroderma-related disorders, including Raynaud's phenomenon, suggested a number between 250,000 and 992,500. (Source: excerpt from Handout on Health Scleroderma: NIAMS) ... The estimated number of people with any type of scleroderma varies from study to study but may range from 1 to 4 affected individuals for every 10,000 Americans (or as many as 1 out of 2500 individuals). (Source: excerpt from Understanding Autoimmune Disease: NIAID)
The following statistics relate to the prevalence of Scleroderma:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Scleroderma.
The cause of scleroderma is unknown. Known risk factors include exposure to silica dust and polyvinyl chloride.
Scleroderma affects more females than men, especially between ages 30 and 50. Approximately 30% of patients with scleroderma die within 5 years of onset.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Source: The 5-Minute Pediatric Consult, 2008
The term 'prevalence' of Scleroderma usually refers to the estimated population
of people who are managing Scleroderma at any given time.
The term 'incidence' of Scleroderma refers to the annual diagnosis rate,
or the number of new cases of Scleroderma diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
Footnotes:
1. Rose and Mackay, 1998, The Autoimmune Diseases, Third Edition
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