For details see prevalence of types of Sex chromosome conditions analysis; summary of available prevalence data:
For details see incidence of types of Sex chromosome conditions analysis; summary of available incidence by type data:
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Approximately 75% of all cases of trisomy 13 syndrome are caused by chromosomal nondisjunction. About 20% are due to chromosomal translocation involving a rearrangement of chromosomes 13 and 14. About 5% are estimated to be mosaics; the clinical effects in these cases may be less severe.
Incidence is estimated to be 1 in every 5,000 neonates. The risk of chromosomal abnormalities typically increases with advanced maternal age; however, the mean maternal age for this abnormality is about 31 years.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Most cases of trisomy 18 syndrome are caused by spontaneous meiotic nondisjunction. The risk of chromosomal abnormalities typically increases with maternal age; however, the mean maternal age for this disorder is 32½. Incidence is 1 in 3,000 neonates, with females three times more likely to be affected than males.
Source: Professional Guide to Diseases (Eighth Edition), 2005
The term 'prevalence' of Sex chromosome conditions usually refers to the estimated population of people who are managing Sex chromosome conditions at any given time. The term 'incidence' of Sex chromosome conditions refers to the annual diagnosis rate, or the number of new cases of Sex chromosome conditions diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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