Diseases » Sexual Conditions » Diagnosis

Diagnosis of Sexual Conditions

Sexual Conditions Diagnosis: Book Excerpts

• Ask the following questions - DYSPAREUNIA
• Ask the Following Questions - IMPOTENCE
• Ask the Following Questions - VAGINAL DISCHARGE
• Differential Diagnosis - Dyspareunia
• Differential Diagnosis - Vaginal Discharge
• Differential Diagnosis - Genital Skin Lesions
• Differential Diagnosis - Vaginal Discharge
• Approach to the Diagnosis - DYSPAREUNIA
• Approach to the Diagnosis - IMPOTENCE
• Approach to the Diagnosis - VAGINAL DISCHARGE
• History and physical examination - Genital lesions in the male
• History and physical examination - Impotence
• History and physical examination - Vaginal discharge
• Diagnosis - Dyspareunia
• Sexual history - Introduction Sexual Disorders
• Diagnosis - Genital herpes
• Diagnosis - Genital warts
• History and physical examination - Dyspareunia
• History and physical examination - Genital lesions in the male
• History and physical examination - Impotence
• History and physical examination - Vaginal discharge
• History - Impotence
• History (2) - Vaginal Discharge
• Differential Overview - Vaginal Discharge
• Differential Overview - Genital Ulcer
• History - Genital lesions in the male
• History - Vaginal discharge
• Clinical Features and Diagnosis - Vaginal Discharge
• History and physical examination - Impotence
• History and physical examination - Vaginal discharge
• History and physical examination - Genital lesions, male
• Approach to the Diagnosis - DYSPAREUNIA
• Approach to the Diagnosis - IMPOTENCE
• Approach to the Diagnosis - VAGINAL DISCHARGE

Diagnostic Tests for Sexual Conditions: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about diagnostis of Sexual Conditions.

DYSPAREUNIA: Ask the following questions:
(Algorithmic Diagnosis of Symptoms and Signs)

1. Does the history indicate that the difficulty is on penetration? Difficulties on penetration usually point to a vulval or vaginal origin for the problem. In that case, bartholinitis, vulvitis, vulval dystrophy, cystitis, urethritis, and urethral caruncle should be suspected.
2. Is the urinalysis abnormal? An abnormal urinalysis may indicate cystitis or a bladder calculus.
3. Are there abnormalities on rectal examination? Hemorrhoids, anal fissures, and impacted feces may cause dyspareunia.
4. Is the pelvic examination totally normal? If this is true, one would consider functional dyspareunia, or it may be that the patient does not have dyspareunia at all and simply has no sexual desire or dislikes the sexual act.

DIAGNOSTIC WORKUP

It is extremely important to look for evidence of sexual abuse both on history and physical examination before undertaking an expensive workup. Routine studies include a CBC, sedimentation rate, urinalysis, urine culture and sensitivity, and vaginal smear and culture. A Pap smear should also be done. If pregnancy is suspected, a pregnancy test should be done. If there is a pelvic mass, pelvic ultrasound may be helpful. A referral to a gynecologist is usually made before ordering this study, however. If vulval dystrophy is suspected, a vaginal biopsy may be useful. If the vaginal examination is normal, perhaps a psychiatrist should be consulted.

 

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Source: Algorithmic Diagnosis of Symptoms and Signs, 2003

IMPOTENCE: Ask the Following Questions:
(Algorithmic Diagnosis of Symptoms and Signs)

1. Is there a history of alcohol or drug ingestion? A host of antihypertensive drugs, including the beta-blockers, may cause impotence. In addition, tricyclic drugs, nicotine, and alcohol intoxication may cause impotence.
2. Is there loss of secondary sex characteristics? These findings suggest Fröhlich's syndrome, Klinefelter's syndrome, and other congenital disorders.
3. Are there abnormalities on urologic examination? Various conditions such as Peyronie's disease, atrophied testes, prostatitis, and Leriche's syndrome may be found on urologic examination.
4. Are there abnormalities on the neurologic examination? Neurologic examination may reveal diabetic neuropathy, spinal cord tumor, multiple sclerosis, and other neurologic disorders.

DIAGNOSTIC WORKUP

A thorough psychiatric and sexual history is necessary before undertaking expensive laboratory tests. It is wise to interview the spouse or sexual partner also because the symptom may be exaggerated by the patient. Do not hesitate to order a drug screen. Routine tests include a CBC and differential count, a urinalysis, a urine culture and colony count, a chemistry panel, VDRL test, thyroid profile, serum testosterone, and gonadotrophin assay. A referral to a urologist is probably wise at this point. He will work up the patient further with a nocturnal tumescent study, Doppler ultrasonography, and penile blood pressure studies. In addition, he may want to do a cystoscopy. It may be wise to perform a postage stamp test before referral for a formal tumescence study.

Nerve conduction velocity studies and EMGs may be needed to rule out diabetic neuropathy. MRI of the spine, cystometric studies, and SSEP studies will help to rule out multiple sclerosis and other spinal cord lesions. A sacral reflex latency time may be very helpful in diagnosing sacral nerve injury. A spinal tap may help rule out central nervous system lues. Angiography may be needed to exclude a Leriche's syndrome.

 

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Source: Algorithmic Diagnosis of Symptoms and Signs, 2003

VAGINAL DISCHARGE: Ask the Following Questions:
(Algorithmic Diagnosis of Symptoms and Signs)

1. Is it purulent? A purulent vaginal discharge suggests nonspecific bacterial vaginitis and gonorrhea.
2. Is it frothy and yellow? This type of discharge is very often due to trichomoniasis vaginitis.
3. Is it cheesy and associated with itching? These findings suggest candidiasis vaginitis.
4. Is it watery and bloodstained? This type of discharge suggests carcinoma of the cervix or endometrium, polyps, hydatidiform mole, and chronic cervicitis. If a frankly bloody discharge is noted, consult the differential diagnosis discussed on page 309 .
5. Is it offensive smelling? An offensive smelling discharge would suggest foreign body in the vagina.
6. Is there inflammation of the cervix? The presence of cervical inflammation would suggest chronic cervicitis and gonorrhea.

DIAGNOSTIC WORKUP

The most important test is microscopic examination of a saline and potassium hydroxide preparation. This will diagnose most cases of trichomoniasis and candidiasis. Gardnerella vaginalis can be diagnosed if clue cells are found, and the pH of the discharge will be greater than 4.7. If this is unrevealing, a Gram stain for gonorrhea and cultures for trichomoniasis, candidiasis, chlamydia, Gardnerella vaginalis , and gonorrhea may be done. A Pap smear should be done to rule out malignancy. Polyps or inflamed areas of the cervix should be biopsied. Colposcopy may help further differentiate a cervical lesion. A dilation and curettage may be necessary to diagnose endometrial carcinoma and hydatidiform mole. Occasionally, pelvic ultrasound and CT scans are necessary. However, before ordering these expensive diagnostic tests, a gynecologist should be consulted. Patients with documented evidence of gonorrhea should have a VDRL test and HIV testing.

 

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Source: Algorithmic Diagnosis of Symptoms and Signs, 2003

Dyspareunia: Differential Diagnosis
(In a Page: Signs and Symptoms)

• Definitions
  –Sexual pain disorder: Persistent or recurrent genital pain of nonorganic cause associated with sexual stimulation, thus causing personal stress; subcategories include dyspareunia and vaginismus
  –Superficial dyspareunia: Pain or dysfunction felt upon initial penetration
  –Deep dyspareunia: Pain or dysfunction felt deep within the pelvis during intercourse
  –Vaginismus: Painful involuntary spasm of the vagina, preventing intercourse
  –Vulvar vestibulitis: A chronic and persistent clinical syndrome characterized by severe pain with vestibular touch or attempted vaginal entry, tenderness in response to pressure within the vulvar vestibule, and physical findings confined to various degrees of vestibular erythema
  –Vulvodynia: Chronic vulvar discomfort (e.g. burning, stinging, irritation, rawness)

• Neurologic etiologies: Nerve damage or infection, dysesthetic (essential) vulvodynia
• Gynecologic etiologies: Gynecologic tumors (e.g., vulvar, cervical, uterine, ovarian, or rectal cancer; fibroids), Bartholin's gland inflammation
• GI: Constipation, irritable bowel syndrome, colitis, diverticulitis, GI tumors (in pelvis)
• Urinary: Interstitial cystitis, urethritis, urethral diverticulum
• Infectious: Endometritis, vaginitis, PID, salpingitis, vulvovaginitis, herpes genitalis, post-herpetic neuralgia, Bartholin's abscess
• Dermatologic etiologies: Vaginal atrophy, lichen sclerosis, Behçet syndrome, contact dermatitis
• Musculoskeletal: Pelvic floor myopathy, fibromyalgia, levator ani myalgia, dysfunctional vaginismus
• Endocrine: Estrogen deficiency, endometriosis
• Psychiatric: Female sexual dysfunction(s)
• Iatrogenic: Surgical (e.g., pelvic adhesions, episiotomy, strictures), pharmacologic (drying soaps or agents, topical medications, OCPs)
• Trauma: Vaginal lacerations or ecchymoses
• Primary pain disorder
• Severely retroverted uterus
• Imperforate hymen

Workup and Diagnosis

• History and physical examination with pelvic and rectal exams
  –Timing: Onset (e.g., upon entry, after intercourse), duration, persistence after intercourse, prior occurrence(s)
  –Associations: Symptoms may occur with all vaginal or vulvar contact, with intercourse only, with exams only, with masturbation, or with memories or recollections of prior occurrences or traumatic experiences
  –Alleviating and aggregating factors during intercourse
  –Qualifiers: Burning, sharp, dull, aching, throbbing, stabbing
  –Old medical records may be of crucial importance
  –Include complete psychiatric history and exam
• Cervical and/or vulvar cultures and microscopic evaluation of normal saline and potassium hydroxide wet mounts should be done
• Imaging studies may be indicated, including pelvic and/or abdominal ultrasound and/or CT scan
• Management of psychiatric causes is particularly challenging and requires specific and specialized therapy
• Consider gynecology and/or psychiatry consult

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Source: In a Page: Signs and Symptoms, 2004

Vaginal Discharge: Differential Diagnosis
(In a Page: Signs and Symptoms)

• Physiologic
  –Many women will have a consistent, slightly clear, non-odor-producing discharge, either midcycle or premenstrually, particularly if they are on oral contraceptives
  –A change in odor, consistency, or color of discharge may signify that evaluation is necessary
  –Increased discharge is associated with pregnancy
• Sexually transmitted disease
  –Trichomonas vaginalis: “Strawberry cervix” with punctate erythema, flagellated oval organisms on wet mount
  –Gonorrhea/Chlamydia may be associated with pelvic pain/dysmenorrhea and dyspareunia
• Bacterial vaginosis
  –Various organisms and changes in normal flora with a characteristic fishy odor
  –Not considered an STD
  –Increases the risk of preterm delivery in pregnant women

• Alteration of normal vaginal flora and/or inflammatory response
  –Candida albicans overgrowth is more common with recent antibiotic use, poorly controlled diabetes, and/or pregnancy; presents with intensely pruritic, inflamed, and erythematous introitus
  –Doderlein's cytolysis (caused by an overgrowth of lactobacilli)

• Atrophic vaginitis
  –Common in postmenopausal women, especially those not on HRT
  –Poor coital lubrication, dyspareunia
  –Dysuria due to atrophic urethral tissue
• Foreign body vaginitis (e.g., retained tampon)
• Noninfectious irritant/allergic contact vaginitis (e.g., soaps, feminine pads, perfumes)
• Cervicitis (usually due to gonorrhea or Chlamydia)
• Cervical dysplasia, cancer, or polyps
• Vaginal or vulvar trauma or cancer

Workup and Diagnosis

• A focused history and physical examination are crucial, including a complete sexual and exposure history, and full abdominal and pelvic examination
  –A wet mount and KOH of the discharge are imperative
  –pH of the discharge may aid in diagnosis
  –A whiff test is done by smelling the discharge after KOH is added; a positive test reveals a fishy odor characteristic of bacterial vaginosis
• Initial labs may include CBC, urinalysis, urine culture, β-hCG, and gonorrhea and Chlamydia cultures
• Test and treat for other STDs when one STD is found (HIV, hepatitis B and C, syphilis)

pH	Discharge	Odor	Wet Mount
Trich >4.5	yellow-green, copious	present	motile, flagellated
BV >4.5	white-grey	fishy	clue cells
Candida <4.5	white, curd-like	none	pseudo-hyphae
GC/chlamydia	mucopurulent	varies	PMNs
Atrophic vaginitis	thin, gray, watery	none	few epithelial cells

>

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Source: In a Page: Signs and Symptoms, 2004

Genital Skin Lesions: Differential Diagnosis
(In a Page: Signs and Symptoms)

• Herpes simplex virus (HSV-1 and HSV-2) is the most common cause of genital lesions in the U.S.
  –Presents with prodromal tingling and genital discomfort before lesions
  –Lesions are always painful and appear as grouped vesicles on an erythematous base
• Condyloma acuminatum (“warts,” HPV)
  –Etiologic agent is human papilloma virus
  –Lesions usually painless and pearly with a smooth surface but may be filiform, fungating, and lobulated

Tinea cruris
–Inguinal erythema with itch or tenderness
–Always spares the scrotum

Candida intertrigo
–Inguinal erythema with itch or tenderness
–Often very red with satellite lesions
–Frequently involves the labia or scrotum

Syphilis
–Primary stage: Painless solitary ulcer (chancre) on labia, penis, or oral mucosa that heals in 2–3 weeks
–Secondary stage: Condyloma lata (moist hypertrophic papules on genital and oral regions)
–Tertiary stage: Cardiac, neurologic, and other systemic effects

• Molluscum contagiosum
  –Multiple, very small, painless, flesh-colored nodules with umbilicated centers

• Chancroid
  –Etiologic agent is Haemophilus ducreyi
  –Painful, solitary, and erythematous lesions
  –May present with dyspareunia and/or dysuria

Erythrasma

Lymphogranuloma venereum

Granuloma inguinale

Behçet syndrome
–Oral and genital ulcers, retinitis, uveitis

Lichen planus

Scabies

Zoon's plasma cell balanitis

Less common etiologies (“zebras”) include inverse psoriasis, seborrheic dermatitis, genital squamous cell carcinoma, extramammary Paget's disease, plaque psoriasis, and fixed drug eruptions

Workup and Diagnosis

• History and physical examination including a sexual history and a complete skin exam
  –Separate lesions into painless and painful categories; however, note that an initially painless lesion may become painful following a secondary infection
• Viral culture is gold standard for HSV detection
• Tzanck test may be used to detect HSV and will reveal multinucleated giant cells and intranuclear inclusions
• RPR or VDRL serum tests screen for syphilis, but become positive only 6–8 weeks after primary infection
  –These tests have high false-positive rates
  –Serum FTA is more specific for syphilis
  –Early diagnosis of primary disease requires dark-field microscopic evaluation of infected tissue or IgM assay
  • Culture or Gram stain to detect chancroid
  • Condyloma accuminata can be diagnosed by applying acetic acid to lesions, which will turn acetowhite
  • Molluscum contagiosum is diagnosed by appearance
  • Wood's lamp may be used to detect erythrasma
  • Shave biopsy is diagnostic for psoriasis, Zoon's, and neoplasms
  • Lesions in older patients that are changing in size, appearance, or texture should always be biopsied to rule out carcinoma
  • All patients with a suspected STD require a full workup for HIV, syphilis, hepatitis B and C, and pregnancy

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Source: In a Page: Signs and Symptoms, 2004

Vaginal Discharge: Differential Diagnosis
(In A Page: Pediatric Signs and Symptoms)

• Physiologic leukorrhea
  –In newborns for 2–3 weeks, due to maternal estrogen effect, and in pubertal girls
  –Discharge typically clear to white, sticky, and nonirritating
  –Newborns may have withdrawal bleeding

• Infections
  –Bacterial vaginosis: Previously known as nonspecific vaginitis; polymicrobial in etiology (coliforms, streptococci, Gardnerella); discharge may be gray and malodorous (fishy smell) but generally nonirritating
  –Candida: Discharge may be cheesy and white with erythematous, pruritic, irritated vulva; typical discharge is rarely seen in prepubertal children; discharge typically has no odor
  –Trichomonas: Discharge may be frothy, malodorous, creamy, green, bloody, or pruritic (or asymptomatic)
  –Chlamydia: Commonly asymptomatic or a nonspecific discharge
  –Gonorrhea: Infection is commonly asymptomatic or has a gray-white, thick, purulent discharge
  –Group A β-hemolytic streptococci: Discharge may be bloody
  –Shigella: Discharge may be bloody

• Irritation/hygiene
  –Due to bubble baths and other chemical irritants, tight clothing, obesity, poor wiping
• Foreign body
  –Commonly includes toilet paper, forgotten tampon
  –Discharge is often bloody and malodorous
• Anatomic
  –Ectopic urethra
  –Rectovaginal fistula
  –Urethral prolapse
• Urinary tract infection
• Masturbation
• Sarcoma botyroides
• Oral contraceptives (estrogen effect)

Workup and Diagnosis

• History
  –Age of girl (pubertal vs prepubertal)
  –Sexual activity and number of partners
  –Possibility of sexual abuse
  –Medications (e.g., steroid, oral contraceptive, antibiotic)
  –PMH of diabetes mellitus or immunocompromised
  –Type of discharge and duration of symptoms
  –Hygiene practices including feminine hygiene products, soaps, wiping techniques
  –Therapy tried at home

• Physical exam
  –Frog-leg or lithotomy position; examine external genitalia for abnormalities; speculum exam in sexually active adolescents
  –Amount, odor, color, consistency of discharge

• Labs
  –pH: Normal in the pubertal female is 3.8–4.4; if >5, consider bacterial vaginosis or Trichomonas
  –Vaginal gram stain and culture
  –Cultures for gonorrhea and Chlamydia (DNA amplification may not hold up in court for abuse cases)
  –Wet prep: Trichomonas has motile trichomonads; bacterial vaginosis has clue cells (vaginal epithelial cells coated with bacteria)
  –KOH for Candida
  –Whiff test (KOH added to discharge yields a fishy smell in Trichomonas)

• Urine culture and pregnancy test as indicated by history

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Source: In A Page: Pediatric Signs and Symptoms, 2007

DYSPAREUNIA: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

The approach to this diagnosis includes an examination of both male and female genital organs and counseling by an understanding physician if these examinations are negative.

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Source: Differential Diagnosis in Primary Care, 2007

IMPOTENCE: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

A careful examination of the external genitalia, the prostate, and secondary sex characteristics is essential. The laboratory workup may include a glucose tolerance test, blood testosterone and cortisol levels, thyroid function studies, a spinal tap, a skull x-ray, and a chromosomal analysis. A nocturnal penile tumescence study is performed to rule out organic causes. If the physical examination is normal, it may be wise to administer psychometric tests or to refer the patient to a psychiatrist before doing an extensive endocrine and neurologic workup. A sympathetic physician may be able to find the supratentorial cause and cure it with a few long discussions with the patient. A female physician may have more success in this area than a male.

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Source: Differential Diagnosis in Primary Care, 2007

VAGINAL DISCHARGE: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

To workup a vaginal discharge, simply examining a fresh wet saline and KOH (10%) preparation will expose the most common offenders, namely Trichomonas and Candida. Some physicians treat all patients with negative findings on these examinations as a nonspecific bacterial vaginitis, but this is not a particularly scientific procedure. It is best to do a smear and culture (especially for gonococci). Cultures are also available for Trichomonas and Candida. If gonorrhea is suspected, material from the endocervix should be cultured. Chlamydia cultures are routinely done in some clinics.

Obviously, if the cervix is eroded and the discharge seems to be coming from there, biopsy and conization may be indicated. Referral to a gynecologist is preferred if this procedure is deemed necessary; however, the primary physician may prefer to cauterize the superficial lesions. Patients with discharges thought to be due to lesions beyond the cervix should probably be referred.

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Source: Differential Diagnosis in Primary Care, 2007

Genital lesions in the male: History and physical examination
(Handbook of Signs & Symptoms (Third Edition))

Begin by asking the patient when he first noticed the lesion. Did it erupt after he began taking a new drug or after a trip out of the country? Has he had similar lesions before? If so, did he get medical treatment for them? Find out if he has been treating the lesion himself. If so, how? Does the lesion itch? If so, is the itching constant or does it bother him only at night? Note whether the lesion is painful. Ask for a description of any drainage from the lesions. Next, take a complete sexual history, noting the frequency of relations, number of sexual partners, and pattern of condom use.

Before you examine the patient, observe his clothing. Do his pants fit properly? Tight pants or underwear, especially those made of nonabsorbent fabrics, can promote the growth of bacteria and fungi. Examine the entire skin surface, noting the location, size, color, and pattern of the lesions. Do genital lesions resemble lesions on other parts of the body? Palpate for nodules, masses, and tenderness. Also, look for bleeding, edema, or signs of infection, such as purulent drainage or erythema. Finally, take the patient’s vital signs.

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Source: Handbook of Signs & Symptoms (Third Edition), 2006

Impotence: History and physical examination
(Handbook of Signs & Symptoms (Third Edition))

If the patient complains of impotence or of a condition that may be causing it, let him describe his problem without interruption. Then begin your examination in a systematic way, moving from less sensitive to more sensitive matters. Begin with a psychosocial history. Is the patient married, single, or widowed? How long has he been married or had a sexual relationship? What’s the age and health status of his sexual partner? Is he feeling stress or pressure from his partner to conceive a child? Find out about past marriages, if any, and ask him why he thinks they ended. If you can do so discreetly, ask about sexual activity outside marriage or his primary sexual relationship. Also ask about his job history, his typical daily activities, and his living situation. How well does he get along with others in his household?

Focus your medical history on the causes of erectile dysfunction. Does the patient have type 2 diabetes mellitus, hypertension, or heart disease? If so, ask about its onset and treatment. Also ask about neurologic diseases such as multiple sclerosis. Obtain a surgical history, emphasizing neurologic, vascular, and urologic surgery. If trauma may be causing the patient’s impotence, find out the date of the injury as well as its severity, associated effects, and treatment. Ask about alcohol intake, drug use or abuse, smoking, diet, and exercise. Obtain a urologic history, including voiding problems and past injury.

Next, ask the patient when his impotence began. How did it progress? What’s its current status? Make your questions specific, but remember that he may have difficulty discussing sexual problems or may not understand the physiology involved.

The following sample questions may yield helpful data: When was the first time you remember not being able to initiate or maintain an erection? How often do you wake in the morning or at night with an erection? Do you have wet dreams? Has your sexual drive changed? How often do you try to have intercourse with your partner? How often would you like to? Can you ejaculate with or without an erection? Do you experience orgasm with ejaculation?

Ask the patient to rate the quality of a typical erection on a scale of 0 to 10, with 0 being completely flaccid and 10 being completely erect. Using the same scale, also ask him to rate his ability to ejaculate during sexual activity, with 0 being never and 10 being always.

Next, perform a brief physical examination. Inspect and palpate the genitalia and prostate for structural abnormalities. Assess the patient’s sensory function, concentrating on the perineal area. Next, test motor strength and deep tendon reflexes in all extremities, and note other neurologic deficits. Take the patient’s vital signs and palpate his pulses for quality. Note any signs of peripheral vascular disease, such as cyanosis and cool extremities. Auscultate for abdominal aortic, femoral, carotid, or iliac bruits, and palpate for thyroid gland enlargement.

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Source: Handbook of Signs & Symptoms (Third Edition), 2006

Vaginal discharge: History and physical examination
(Handbook of Signs & Symptoms (Third Edition))

Ask the patient to describe the onset, color, consistency, odor, and texture of her vaginal discharge. How does the discharge differ from her usual vaginal secretions? Is the onset related to her menstrual cycle? Also, ask about associated symptoms, such as dysuria and perineal pruritus and burning. Does she have spotting after coitus or douching? Ask about recent changes in her sexual habits and hygiene practices. Is she or could she be pregnant? Next, ask if she has had vaginal discharge before or has ever been treated for a vaginal infection. What treatment did she receive? Did she complete the course of medication? Ask about her current use of medications, especially antibiotics, oral estrogens, and hormonal contraceptives.

Examine the external genitalia and note the character of the discharge. (See Identifying causes of vaginal discharge.) Observe vulvar and vaginal tissues for redness, edema, and excoriation. Palpate the inguinal lymph nodes to detect tenderness or enlargement, and palpate the abdomen for tenderness. A pelvic examination may be required. Obtain vaginal discharge specimens for testing.

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Source: Handbook of Signs & Symptoms (Third Edition), 2006

Dyspareunia: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

Physical examination and laboratory tests help determine the underlying disorder. Diagnosis also depends on a detailed sexual history and the answers to such questions as: When does the pain occur? Does it occur with certain positions or techniques or at certain times during the sexual response cycle? Where does the pain occur? What’s its quality, frequency, and duration? What factors relieve or aggravate it?

When the disorder causes marked distress or interpersonal difficulty, it may fulfill the diagnostic criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Introduction: Sexual Disorders: Sexual history
(Professional Guide to Diseases (Eighth Edition))

Careful assessment helps identify the cause of a sexual problem as psychological or physical. A sexual history provides the basis for prevention, diagnosis, and treatment.

❑ Ensure privacy, as for physical assessment. Allow sufficient time so that the patient doesn’t feel rushed.

❑ Approach a sexual history objectively. Remember, sexual health is relative; avoid making assumptions or judgments about the patient’s sexual activities.

❑ After listening to the patient, determine his level of sexual understanding and phrase your questions in language that he can understand. Avoid technical terms.

❑ Begin with the least threatening questions. Usually, a menstrual or urologic history helps lead into a sexual history.

❑ Inquire about what the patient accepts as normal sexual behavior. Ask about sexual needs and priorities and whether the patient can discuss them with a sex partner.

❑ Assess risk behavior concerning selection of sex partners and specific sexual practices.

❑ Ask about possible homosexual activity, which can influence the risk and treatment of some STDs.

❑ Ask the female patient if she has adequate lubrication during intercourse and if she has ever experienced orgasm or pain with sexual contact. Ask the male patient if he has ever had difficulties with erection or ejaculation.

❑ Ask about current or past contraceptive practices.

❑ Try to use the history therapeutically by encouraging the patient to express anxiety. Such fears may be alleviated simply by providing factual information and answering questions.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Genital herpes: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

Diagnosis is based on the physical examination and patient history. Helpful (but nondiagnostic) measures include laboratory data showing increased antibody titers, smears of genital lesions showing atypical cells, and cytologic preparations (Tzanck test) that reveal giant cells.

CONFIRMING DIAGNOSIS Diagnosis can be confirmed by demonstration of the herpes simplex virus in vesicular fluid, using tissue culture techniques, or by antigen tests that identify specific antigens.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Genital warts: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

Dark-field examination of scrapings from wart cells shows marked vascularization of epidermal cells, which helps to differentiate genital warts from condylomata lata associated with second-stage syphilis. Applying 5% acetic acid (white vinegar) to the warts turns them white. Warts usually are diagnosed early by visual inspection; biopsy is indicated only when neoplasia is strongly suspected.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Dyspareunia: History and physical examination
(Professional Guide to Signs & Symptoms (Fifth Edition))

Begin by asking the patient to describe the pain. Does it occur with attempted penetration or deep thrusting? How long does it last? Is the pain intermittent or does it always accompany intercourse? Ask whether changing coital position or using a vaginal lubricant relieves the pain.

Next, ask about a history of pelvic, vaginal, or urinary tract infection. Does the patient have signs and symptoms of a current infection? Have her describe any discharge. Also, ask about malaise, headache, fatigue, abdominal or back pain, nausea and vomiting, and diarrhea or constipation.

Obtain a sexual and menstrual history. Determine whether dyspareunia is related to the patient’s menstrual cycle. Are her cycles regular? Ask about dysmenorrhea and metrorrhagia. Has the patient had a baby? If so, did she have an episiotomy? Note whether she’s breast-feeding. Ask about previous abortion, sexual abuse, or pelvic surgery. Also, find out what contraceptive method the patient uses. Does her partner use condoms? Does he or could he have a latex allergy? Then try to determine her attitude toward sexual intimacy. Does she feel tense during coitus? Is she satisfied with the length of foreplay? Does she usually achieve orgasm? Ask about a history of rape, incest, or sexual abuse as a child.

Next, perform a physical examination, starting with vital signs. Palpate the abdomen for tenderness, pain, or masses and for inguinal lymphadenopathy. Finally, inspect the genitalia for lesions and vaginal discharge.

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Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

Genital lesions in the male: History and physical examination
(Professional Guide to Signs & Symptoms (Fifth Edition))

Begin by asking the patient when he first noticed the lesion. Did it erupt after he began taking a new drug or after a trip out of the country? Has he had similar lesions before? If so, did he get medical treatment for them? Find out if he has been treating the lesion himself. If so, how? Does the lesion itch? If so, is the itching constant or does it bother him only at night? Note whether the lesion is painful. Ask for a description of any drainage from the lesion. Next, take a complete sexual history, noting the frequency of relations, the number of sexual partners, and the pattern of condom use.

Before you examine the patient, observe his clothing. Do his pants fit properly? Tight pants or underwear, especially those made of nonabsorbent fabrics, can promote the growth of bacteria and fungi. Examine the entire skin surface, noting the location, size, color, and pattern of the lesions. Do genital lesions resemble lesions on other parts of the body? Palpate for nodules, masses, and tenderness. Also, look for bleeding, edema, or signs of infection, such as purulent drainage or erythema. Finally, take the patient’s vital signs.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

Impotence: History and physical examination
(Professional Guide to Signs & Symptoms (Fifth Edition))

If the patient complains of impotence or of a condition that may be causing it, let him describe his problem without interruption. Then begin your examination in a systematic way, moving from less sensitive to more sensitive matters. Begin with a psychosocial history. Is the patient married, single, or widowed? How long has he been married or had a sexual relationship? What’s the age and health status of his sexual partner? Find out about past marriages, if any, and ask him why he thinks they ended. If you can do so discreetly, ask about sexual activity outside marriage or his primary sexual relationship. Also ask about his job history, his typical daily activities, and his living situation. How well does he get along with others in his household?

Focus your medical history on the causes of erectile dysfunction. Does the patient have type 2 diabetes mellitus, hypertension, or heart disease? If so, ask about its onset and treatment. Also ask about neurologic diseases such as multiple sclerosis. Obtain a surgical history, emphasizing neurologic, vascular, and urologic surgery. If trauma may be causing the patient’s impotence, find out the date of the injury as well as its severity, associated effects, and treatment. Ask about intake of alcohol, drug use or abuse, smoking, diet, and exercise. Obtain a urologic history, including voiding problems and past injury.

Next, ask the patient when his impotence began. How did it progress? What’s its current status? Make your questions specific, but remember that many patients have difficulty discussing sexual problems, and many don’t understand the physiology involved.

The following sample questions may yield helpful data: When was the first time you remember not being able to initiate or maintain an erection? How often do you wake in the morning or at night with an erection? Do you have wet dreams? Has your sexual drive changed? How often do you try to have intercourse with your partner? How often would you like to? Can you ejaculate with or without an erection? Do you experience orgasm with ejaculation?

Ask the patient to rate the quality of a typical erection on a scale of 0 to 10, with 0 being completely flaccid and 10 being completely erect. Using the same scale, also ask him to rate his ability to ejaculate during sexual activity, with 0 being never and 10 being always.

Next, perform a brief physical examination. Inspect and palpate the genitalia and prostate for structural abnormalities. Assess the patient’s sensory function, concentrating on the perineal area. Next, test motor strength and deep tendon reflexes in all extremities, and note other neurologic deficits. Take the patient’s vital signs and palpate his pulses for quality. Note any signs of peripheral vascular disease, such as cyanosis and cool extremities. Auscultate for abdominal aortic, femoral, carotid, or iliac bruits, and palpate for thyroid gland enlargement.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

Vaginal discharge: History and physical examination
(Professional Guide to Signs & Symptoms (Fifth Edition))

Ask the patient to describe the onset, color, consistency, odor, and texture of her vaginal discharge. How does the discharge differ from her usual vaginal secretions? Is the onset related to her menstrual cycle? Also, ask about associated symptoms, such as dysuria and perineal pruritus and burning. Does she have spotting after coitus or douching? Ask about recent changes in her sexual habits and hygiene practices. Is she or could she be pregnant? Next, ask if she has had a vaginal discharge before or has ever been treated for a vaginal infection. What treatment did she receive? Did she complete the course of medication? Ask about her current use of medications, especially antibiotics, oral estrogens, and hormonal contraceptives.

Examine the external genitalia and note the character of the discharge. (See Identifying causes of vaginal discharge, page 792.)  Observe vulvar and vaginal tissues for redness, edema, and excoriation. Palpate the inguinal lymph nodes to detect tenderness or enlargement, and palpate the abdomen for tenderness. A pelvic examination may be required. Obtain vaginal discharge specimens for testing.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

Impotence: History
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)

 A. Basic history. Although written questionnaires may elicit sexual dysfunction, most patients prefer to communicate such issues in the privacy of verbal communication with their primary care provider. For the initial inquiry, simply ask: “Are you sexually active?” For sexual dysfunction evaluation, gender orientation is not relevant to diagnosis or therapy, so that whether the patient is homosexual, heterosexual, or bisexual has no distinct bearing on the diagnostic or therapeutic direction. For persons who are not sexually active, next determine whether this is a matter of choice or an obstacle that prevents sexual activity (e.g., lack of partner, ED, physical disorder).

For persons who are sexually active, a series of follow-up questions will uncover most relevant psychosexual pathology. Begin with: “How would you rate your sex life on a scale of 1 to 10?” If the response is 10, sexual dysfunction is decidedly unlikely. However, most individuals respond, “Oh, about a 7.” Follow with, “What would have to be different to change your sex life from a 7 to a 10?” This forced-choice inquiry often produces responses which directly indicate problematic underlying issues: “Well, if I could just get a good erection.” “If my erection could last more than 30 seconds.” “If my partner didn’t always pick a fight with me and then expect to have sex.”

For impotent men, their response is usually direct and simple, indicating an inability to get or maintain an erection. Follow-up questions should determine the duration and nature of onset. Absence of morning erections should be sought, as this typifies organic impotence. Men who are much more likely to have psychogenic ED are those who report sudden, complete loss of sexual function, or “circumstantial” impotence, for example, (a) good function with one partner, but not another; (b) good erections with masturbation but not with interactive sex; (c) good morning erections, but not at times of interactive sex; or (d) overt anxiety or relationship conflict. Because organic ED generally leads to psychological consequences, many patients suffer a combination of psychogenic and organic impotence.

 B. Inquiry about libido is a crucial diagnostic point for testosterone deficiency. Testosterone is necessary for libido, but not erections. Men who present with good libido have only a remote possibility of having testosterone deficiency.

 C. A medication history should be taken for all men complaining of impotence, recalling that most medication-induced impotence is evident by the temporal relationship between onset of impotence and medication initiation. On the other hand, agents such as thiazides can produce impotence after months of use. Similarly, some antidepressants can produce sexual dysfunction either early or after weeks of therapy. The relationship of medications to impotence can often be clarified by a drug holiday.

Physical examination

Although physical examination is usually not enlightening, general agreement is seen that the genitals should be examined for evidence of overt testicular atrophy, and the penis for Peyronie’s disease. In the latter, inflammatory plaques in the corpora cavernosa produce an area of limited expansile capacity, with subsequent penile deviation on erection which can prevent intromission. A rectal examination to document rectal sensation as well as tone can be complemented by the bulbocavernosus reflex. This reflex is elicited by briskly squeezing the glans penis in one hand while a single digit from the other is in the rectum. A normal examination, indicating an intact reflex arc, is manifest as a rectal contraction in response to the glans squeeze. Prostate examination is pertinent at this point, in the event testosterone therapy is required.

» READ BOOK EXCERPT ONLINE »

Source: The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter, 2000

Vaginal Discharge: History (2)
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)

 A. What is the specific vaginal complaint? Is it soreness, discharge, odor, itching, or dyspareunia? Vaginal soreness correlates with vulvovaginal candidiasis, allergy, contact dermatitis, or atrophy. Yeast, BV, atrophy, and trauma produce significant dyspareunia.

 B. What is the characteristic of the discharge? Is the discharge heavy or light, thick or thin? Does it have an odor? Most women have some physiologic discharge that changes during the menstrual cycle with hormonal flux. BV and T. vaginitis produce malodorous discharge of variable amount. Yeast produces a thick discharge that usually has no odor.

C. What is the sexual history (3)? Is there a new sexual partner in the last year? How does the patient protect herself from sexually transmitted disease? In taking this part of the history, it is key to convey necessary information concerning sexually transmitted disease transmission, both to allay anxiety and to modify behavior, when appropriate.

 D. What is the menstrual history? Ask when was the last period? Are you pregnant? What is your method of contraception? Yeast often overgrows in the vagina premenstrually. Trichomoniasis and BV during pregnancy are associated with premature labor, premature delivery, and septic abortion. Yeast vaginitis is more common during pregnancy and when taking oral contraceptives.

 E. Are you taking any medications? Have you tried any medications for your vaginal problem?

Antibiotics, contraceptive preparations, hormones, vaginal medications, and other OCT preparations often alter the vaginal ecosystem and allow infection to be introduced or normal vaginal flora to become unbalanced. Foreign bodies (e.g., tampons, diaphragms, or condoms) can create vaginal irritations, inflammation, and infections.

 F. If the problem is vaginal irritation, have any substances been used that cause allergic reaction or chemical irritation? Do you douche?

These might include deodorant soaps, feminine hygiene sprays, scented douches, laundry detergent, bath oils, dyed toilet tissue, synthetic clothing, or hot tub or swimming pool chemicals.

At times, only elimination of all possible offending agents, skin testing, or both permit identification of the allergies or irritants.

G. If no obvious infectious, traumatic, or chemical agent is identified, could the vaginal complaint be related to a systemic illness [e.g., diabetes mellitus or human immunodeficiency virus (HIV) infection] or with a life change?

Idiopathic vulvovaginal ulceration can be associated with HIV disease.

Atrophic vaginitis secondary to hormone depletion can cause significant dyspareunia, swelling, and discharge. Collagen-vascular disease, pemphigus, and Bechêt’s syndrome can manifest in vaginal symptoms.

Physical examination (4)

A general physical examination should be performed if systemic illness is suspected. Record vital signs, including temperature, blood pressure, and pulse.

In most cases, a genital examination with the patient in the lithotomy position is adequate.

The external genitalia is carefully inspected for evidence of trauma, blisters, lymph nodes excoriations, swelling, erythema, ulcerations, tenderness or pain.

The amount, color, texture, odor, and location of the discharge should be noted. A complete pelvic examination should be performed with particular attention given to the cervix for evidence of friability or inflammation and a cervical motion test which may indicate pelvic inflammatory disease.

» READ BOOK EXCERPT ONLINE »

Source: The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter, 2000

Vaginal Discharge: Differential Overview
(Field Guide to Bedside Diagnosis)

❑ Physiologic discharge

❑ Candida vulvovaginitis

❑ Bacterial vaginosis

❑ Trichomonas vaginitis

❑ Atrophic vaginitis

❑ Irritant dermatitis

❑ Gonorrheal cervicitis

❑ Chlamydial cervicitis

❑ Herpes simplex

❑ Cervical cancer

Diagnostic Approach

Symptoms of vaginitis include vaginal discharge, pruritis, irritation, soreness, odor, and less commonly bleeding, dysuria, or pain with intercourse. It is important to distinguish burning on urination due to cystitis, which is internal and accompanied by irritative signs (urinary frequency), from dysuria due to vaginitis, which feels external as the urine passes over an inflamed vulva. Similarly, it is important to distinguish vaginitis, characterized by discharge and pruritus, from cervicitis, with discharge and pelvic pain.

On examination, the vulva appears normal in bacterial vaginosis, while erythema, edema or fissures suggest candidiasis, trichomonas or dermatitis. An erythematous, friable cervix with a mucopurulent discharge is consistent with cervicitis rather than vaginitis. This must be distinguished from ectropion (normal endocervical glandular tissue visible on the exocervix), which is not friable.

» READ BOOK EXCERPT ONLINE »

Source: Field Guide to Bedside Diagnosis, 2007

Genital Ulcer: Differential Overview
(Field Guide to Bedside Diagnosis)

❑ Herpes simplex

❑ Trauma

❑ Syphilis

❑ Fixed drug eruption

❑ Behçet syndrome

❑ Candida balanitis

❑ Granuloma inguinale

❑ Chancroid

❑ Lymphogranuloma venereum

❑ Bowen disease

❑ Carcinoma of the penis

Diagnostic Approach

A sexually transmitted infection is by far the most likely cause; therefore, a careful sexual history must be taken. Because the patient is often embarrassed or ashamed, cooperation with accurate information can best be gained by first clearly explaining the purpose of the questions. Therapy is usually initiated based upon a clinical diagnosis. Although classic presentations are useful guides, the appearance of ulcers can be atypical (particularly in HIV), overlap, and multiple agents may be acquired simultaneously.

» READ BOOK EXCERPT ONLINE »

Source: Field Guide to Bedside Diagnosis, 2007

Genital lesions in the male: History
(Signs & Symptoms: A 2-in-1 Reference for Nurses)

Begin by asking the patient when he first noticed the lesion. Did it erupt after he began taking a new drug or after a trip out of the country? Has he had similar lesions before? If so, did he get medical treatment for them? Find out if he has been treating the lesion himself. If so, how? Does the lesion itch? If so, is the itching constant or does it bother him only at night? Note whether the lesion is painful. Ask for a description of any drainage from the lesions. Next, take a complete sexual history, noting the frequency of relations, number of sexual partners, and pattern of condom use.

» READ BOOK EXCERPT ONLINE »

Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

Vaginal discharge: History
(Signs & Symptoms: A 2-in-1 Reference for Nurses)

Ask the patient to describe the onset, color, consistency, odor, and texture of her vaginal discharge. How does the discharge differ from her usual vaginal secretions? Is the onset related to her menstrual cycle? Also, ask about associated symptoms, such as dysuria and perineal pruritus and burning. Does she have spotting after coitus or douching? Ask about recent changes in her sexual habits and hygiene practices. Is she or could she be pregnant? Next, ask if she has had vaginal discharge before or has ever been treated for a vaginal infection. What treatment did she receive? Did she complete the course of medication? Ask about her current use of medications, especially antibiotics, oral estrogens, and contraceptives.

» READ BOOK EXCERPT ONLINE »

Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

Vaginal Discharge: Clinical Features and Diagnosis
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)

Prepubertal Onset

Physiologic Leukorrhea

Maternalestrogen passes across placenta and stimulates hypertrophy of glycogen-containingvaginal squamous epithelial cells in the fetus.

Decrease in serum estrogen after birthleads to shedding of these cells and production of whitish vaginaldischarge that may persist for a few weeks.

Some neonates also may have associatedwithdrawal bleeding secondary to decreased estrogen stimulationof the endometrium.

Vulvovaginitis

Nonspecific Causes

Most commoncause of vaginal discharge in prepubertal girls is nonspecific vaginitis, whichis usually due to poor perineal hygiene and contamination with mixedbowel flora.

Chemical irritants (e.g., bubble bathpreparations, shampoos, and harsh soaps) also may cause vaginitis.

Dysuria is sometimes associated finding.

Specific Infections

Some neonatesacquire T. vaginalis during passage through birth canal, and whitish oryellowish vaginal discharge may persist beyond neonatal period.Seeing motile flagellated organism on wet mount (saline) confirmsdiagnosis.

Infection with Candida species mayproduce whitish or yellowish discharge and vulvar inflammation.Risk factors include diabetes mellitus, use of broad-spectrum antibiotics,and immunodeficiency disorders. KOH preparation or culture of dischargeis diagnostic.

Group A Streptococcus, S. aureus, H.influenzae, S. pneumoniae, and Shigella species may produce foul-smellingvaginal discharge. Diarrhea usually occurs with Shigella vaginitis,and in some cases vaginal discharge contains blood. Positive vaginalculture is diagnostic.

E. vermicularis (pinworm) producesintense anal itching, particularly at night when worms move ontoperianal skin. Persistent scratching may produce secondary vulvovaginitis.Seeing white, threadlike worms, which are about 1 cm in length,or identifying eggs under microscope from cellophane tape preparationis diagnostic.

In prepubertal females, infection withT. vaginalis, herpes simplex virus, N. gonorrhoeae, or C. trachomatisimplies sexual abuse until proven otherwise. Infections with thesepathogens are discussed in sections Pubertal and Postpubertal Onset: Vulvovaginitis,and Cervicitis.

Foreign Body

Foreignbody in vagina causes foul-smelling discharge, which is often associated withpain or bleeding.

Toilet paper, pins, beads, and pencilerasers are some of the objects that may be found.

History and physical exam are usuallydiagnostic.

Radiography of pelvis is useful, especiallyif foreign body is radiopaque. Exam under anesthesia may be necessaryin some cases.

Pubertal and Postpubertal Onset

Physiologic Leukorrhea

Most commoncause of vaginal discharge in pubescent girls.

Cyclic ovarian activity with increasedestrogen secretion produces glycogen-containing vaginal epithelium.Desquamated vaginal cells and mucus produce whitish discharge thatusually starts before menarche and may continue for several years.

Wet preparation shows epithelial cellswith no evidence of inflammation.

Vulvovaginitis

Nonspecific Causes

Contributing factors to nonspecific vulvovaginitisinclude poor hygiene, obesity, chemical irritants, and tight-fittingnylon underpants.

Specific Infections

Primary causes of vaginitis in adolescentsare bacterial vaginosis, Candida species, T. vaginalis, and herpessimplex virus. Because of changes in vaginal epithelium and colonizingflora in puberty, vagina is more resistant to infections causedby N. gonorrhoeae and C. trachomatis. In adolescents these 2 pathogenscause cervicitis rather than vaginitis.

Bacterial Vaginosis

Presenceof vaginal Gardnerella and Mobiluncus species does not necessarilysignify a sexually transmitted disease because these bacteria alsocan occur in sexually inactive girls.

Presence of thin, white, homogenousdischarge; characteristic fishy odor when 1–2 drops of 10% KOHare added to specimen of vaginal discharge; neutral or alkalinevaginal pH; and appearance of small refractile bacteria coatingvaginal epithelial cells (clue cells) on saline wet mount or Gramstain confirm diagnosis.

Candida Species

Infectionwith Candida species produces thick, cheesy pruritic discharge.

Positive KOH preparation demonstratingyeast cells and mycelia or positive vaginal culture is diagnostic.

Trichomonas vaginalis

Infectionwith T. vaginalis usually produces frothy, pale yellow to gray-greendischarge with musty odor.

Although pathogen can survive on fomitevectors (damp clothes, towels), usual source of infection is throughdirect sexual contact.

Presence of motile flagellated organismson wet mount is diagnostic. If wet mount is negative, positive cultureor polymerase chain reaction test confirms diagnosis.

Herpes Simplex Virus

Infectionwith herpes simplex virus 1 (HSV-1) or HSV-2 may produce small painful vesiclesand ulcers on vulva, vagina, or cervix. Vaginal discharge, fever,and inguinal adenopathy also may occur.

Herpetic infections can present asprimary genital infections or as recurrent episodes, especiallywith HSV-2.

Fluorescent antibody staining of vesiclescrapings or positive culture from lesion confirms diagnosis.

Cervicitis

Is an inflammationof the ectocervix, endocervix, or both. T. vaginalis, Candida species,and herpes simplex virus can cause ectocervicitis, whereas C. trachomatisand N. gonorrhoeae are most common pathogens causing endocervicitis.

Typical clinical findings of cervicitisare mucopurulent discharge and inflamed cervix.

Chlamydia trachomatis

Infectionis almost always acquired through sexual contact. It is most prevalentbacterial sexually transmitted disease in U.S. and frequently accompaniesgonococcal genital infections.

Can be asymptomatic or produce mildcervical discharge. Associated findings include dysuria and urinaryfrequency.

Positive endocervical culture or identificationby nucleic acid amplification tests is diagnostic.

Neisseria gonorrhoeae

Transmissionoccurs by direct sexual contact.

Cervix is inflamed and tender and vaginaldischarge is thick creamy yellow.

Positive endocervical culture or identificationby nucleic acid amplification tests is diagnostic.

Pelvic Inflammatory Disease

Is an infectionwith spread of organisms from vagina or cervix to endometrium (endometritis),fallopian tubes (salpingitis, tubal abscess), pelvic peritoneum(pelvic peritonitis), or contiguous structures (oophoritis, tuboovarianabscess).

N. gonorrhoeae, C. trachomatis, andendogenous flora of lower genital tract including anaerobic bacteria(Bacteroides, Peptostreptococcus, Clostridium, and Actinomyces species)and facultative bacteria (E. coli, H. influenzae, Streptococcusspecies) are frequent pathogens.

Cervical and vaginal discharge, lowerabdominal pain, cervical motion tenderness, adnexal tenderness,vomiting, and fever are common findings.

Cervical culture for C. trachomatis,N. gonorrhoeae, and other aerobic and anaerobic bacteria shouldbe performed. Laparoscopy may be required to provide definitivediagnosis in equivocal cases.

Foreign Body

In adolescents,most common foreign body is retained tampon.

Discharge is foul smelling and oftenblood streaked.

Foreign body can usually be visualizedby speculum exam.

Diagnostic Approach

Nonspecificvulvovaginitis is most common cause of vaginal discharge in prepubertal girls.If discharge fails to improve with good perineal hygiene or if itis purulent, specific bacterial infection, sexually transmittedinfection, or foreign body should be suspected. Wet mounts (salineand KOH), Gram stain, and vaginal cultures should be performed.Exam under anesthesia may be necessary for suspected foreign body.

In pubertal girls who are not sexuallyactive, most common causes of vaginal discharge are physiologicleukorrhea, bacterial vaginosis, and C. albicans. Wet preparations(saline and KOH) and Gram stain should be performed. Bacterial andfungal cultures also should be considered.

In girls who are sexually active, thesame diagnoses described for pubertal nonsexually active femalesare possible, but sexually transmitted infections also are likely.In addition to wet preparations and Gram stain, cultures for C.trachomatis, N. gonorrhoeae, and other aerobic and anaerobic bacteria shouldbe performed. In some centers nucleic acid amplification technologyis available for detection of C. trachomatis and N. gonorrhoeaefrom endocervical and urine specimens. Laparoscopy may provide definitivediagnosis in suspected pelvic inflammatory disease with negativecervical cultures.

If sexual abuse is suspected at anyage, vaginal, rectal, and throat cultures for N. gonorrhoeae andvaginal and rectal cultures for C. trachomatis should be performed,even in an asymptomatic child. HIV testing should be considered.So should pregnancy prophylaxis, which depends on whether menarche hasbeen reached and on nature of abuse.

» READ BOOK EXCERPT ONLINE »

Source: The Diagnostic Approach to Symptoms and Signs in Pediatrics, 2006

Impotence: History and physical examination
(Nursing: Interpreting Signs and Symptoms)

If the patient complains of impotence or of a condition that may be causing it, let him describe his problem without interruption. Then begin your examination with a psychosocial history. Is the patient married, single, or widowed? How long has he been married or had a sexual relationship? What's the age and health status of his sexual partner? Is he feeling stress or pressure from his partner to conceive a child? Find out about past marriages, if any, and ask him about his sexual experiences with former spouses. Ask about sexual activity outside marriage or his primary sexual relationship. Also ask about his job history, his typical daily activities, and his living situation. How well does he get along with others in his household?

Focus your medical history on the causes of erectile dysfunction. Does the patient have diabetes mellitus, hypertension, or heart disease? If so, ask about its onset and treatment. Also ask about neurologic diseases such as multiple sclerosis. Obtain a surgical history, emphasizing neurologic, vascular, and urologic surgery. If trauma may be causing the patient's impotence, find out the date of the injury as well as its severity, associated effects, and treatment. Ask about alcohol intake, drug use or abuse, smoking, diet, and exercise. Obtain a urologic history, including voiding problems and past injury.

Next, ask the patient when his impotence began. How did it progress? What's its current status? Make your questions specific, but remember that he may have difficulty discussing sexual problems or may not understand the physiology involved.

Other questions that can help yield helpful data include: When was the first time you remember not being able to initiate or maintain an erection? How often do you wake in the morning or at night with an erection? Do you have wet dreams? Has your sexual drive changed? How often do you try to have intercourse with your partner? How often would you like to? Can you ejaculate with or without an erection? Do you experience orgasm with ejaculation?

Next, perform a brief physical examination. Inspect and palpate the genitalia and prostate for structural abnormalities. Assess the patient's sensory function, concentrating on the perineal area. Next, test motor strength and deep tendon reflexes in all extremities, and note other neurologic deficits. Take the patient's vital signs and palpate his pulses for quality. Note any signs of peripheral vascular disease, such as cyanosis and cool extremities. Auscultate for abdominal aortic, femoral, carotid, or iliac bruits, and palpate for thyroid gland enlargement.

» READ BOOK EXCERPT ONLINE »

Source: Nursing: Interpreting Signs and Symptoms, 2007

Vaginal discharge: History and physical examination
(Nursing: Interpreting Signs and Symptoms)

Ask the patient to describe the onset, color, consistency, odor, and texture of her vaginal discharge. How does the discharge differ from her usual vaginal secretions? Is the onset related to her menstrual cycle? Ask about associated symptoms, such as dysuria and perineal pruritus and burning. Does she have spotting after coitus or douching? Ask about recent changes in her sexual habits and hygiene practices. Is she or could she be pregnant? Ask if she has had vaginal discharge before or has ever been treated for a vaginal infection or sexually transmitted disease. What treatment did she receive? Did she complete the course of medication and were all sexual contacts treated? Ask about her current use of medications, especially antibiotics, oral estrogens, and hormonal contraceptives.

Examine the external genitalia and note the character of the discharge. (See Identifying causes of vaginal discharge.) Observe vulvar and vaginal tissues for redness, edema, and excoriation. Palpate the inguinal lymph nodes to detect tenderness or enlargement, and palpate the abdomen for tenderness. A pelvic examination may be required. Obtain vaginal discharge specimens for testing.

» READ BOOK EXCERPT ONLINE »

Source: Nursing: Interpreting Signs and Symptoms, 2007

Genital lesions, male: History and physical examination
(Nursing: Interpreting Signs and Symptoms)

Begin by asking the patient when he first noticed the lesion. Did it erupt after he began taking a new drug or after a trip out of the country? Has he had similar lesions before? If so, did he get medical treatment for them? Find out if he has been treating the lesion himself. If so, how? Does the lesion itch? If so, is the itching constant or does it bother him only at night? Note whether the lesion is painful. Ask for a description of any drainage from the lesion. Next, take a complete sexual history, noting the frequency of relations, number of sexual partners, and pattern of condom use.

Before you examine the patient, observe his clothing. Do his pants fit properly? Tight pants or underwear, especially those made of nonabsorbent fabrics, can promote the growth of bacteria and fungi. Examine the entire skin surface, noting the location, size, color, and pattern of the lesions. Do genital lesions resemble lesions on other parts of the body? Palpate for nodules, masses, and tenderness. Also, look for bleeding, edema, or signs of infection, such as purulent drainage or erythema. Finally, take the patient's vital signs.

» READ BOOK EXCERPT ONLINE »

Source: Nursing: Interpreting Signs and Symptoms, 2007

DYSPAREUNIA: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

The approach to this diagnosis includes an examination of both male and female genital organs and counseling by an understanding physician if these examinations are negative.

» READ BOOK EXCERPT ONLINE »

Source: Differential Diagnosis in Primary Care, 2007

IMPOTENCE: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

A careful examination of the external genitalia, the prostate, and secondary sex characteristics is essential. The laboratory workup may include a glucose tolerance test, blood testosterone, free testosterone and cortisol levels, thyroid function studies, a spinal tap, a skull x-ray, and a chromosomal analysis. A nocturnal penile tumescence study is performed to rule out organic causes. If the physical examination is normal, it may be wise to administer psychometric tests or to refer the patient to a psychiatrist before doing an extensive endocrine and neurologic workup. A sympathetic physician may be able to find the supratentorial cause and cure it with a few long discussions with the patient. A female physician may have more success in this area than a male.

» READ BOOK EXCERPT ONLINE »

Source: Differential Diagnosis in Primary Care, 2007

VAGINAL DISCHARGE: Approach to the Diagnosis
(Differential Diagnosis in Primary Care)

To workup a vaginal discharge, simply examining a fresh wet saline and KOH (10%) preparation will expose the most common offenders, namely Trichomonas and Candida. Some physicians treat all patients with negative findings on these examinations as a nonspecific bacterial vaginitis, but this is not a particularly scientific procedure. It is best to do a smear and culture (especially for gonococci). Cultures are also available for Trichomonas and Candida. If gonorrhea is suspected, material from the endocervix should be cultured. Chlamydia cultures are routinely done in some clinics. Obviously, if the cervix is eroded and the discharge seems to be coming from there, biopsy and conization may be indicated. Referral to a gynecologist is preferred if this procedure is deemed necessary; however, the primary physician may prefer to cauterize the superficial lesions. Patients with discharges thought to be due to lesions beyond the cervix should probably be referred.

» READ BOOK EXCERPT ONLINE »

Source: Differential Diagnosis in Primary Care, 2007

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Choose ... Alzheimers & Dementia Asthma Child ADHD ADHD in Adults Allergy Hypertension Bipolar Breast Cancer Celiac Disease Crohns Disease Colon Cancer Contraception Diabetes Cancer Depression Erectile Disorder Cholesterol COPD GERD Heartburn/Reflux Metabolic Syndrome Migraine/Headache Multiple Sclerosis Obesity Osteoporosis Overactive Bladder Psoriasis Sexual Disorder Sleep Disorders Smoking The Pill Ulcerative Colitis All Common Mistakes

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