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Diseases » Sjogren's Syndrome » Symptoms
 

Symptoms of Sjogren's Syndrome

Symptoms of Sjogren's Syndrome

The list of signs and symptoms mentioned in various sources for Sjogren's Syndrome includes the 68 symptoms listed below:

Research symptoms & diagnosis of Sjogren's Syndrome:

Sjogren's Syndrome: Complications

Review medical complications possibly associated with Sjogren's Syndrome:

Sjogren's Syndrome Symptoms: Book Excerpts

Diagnostic Testing

Diagnostic testing of medical conditions related to Sjogren's Syndrome:

  • Schirmer 1 test - a test of eyelid wetness
  • Schirmer 2 test - a test of nasal wetness
  • Eye stain dye tests
  • Rose bengal
  • Lissamine green
  • more tests...»

Research More About Sjogren's Syndrome

Do I have Sjogren's Syndrome?

Sjogren's Syndrome: Undiagnosed Conditions

Diseases that may be commonly undiagnosed in related medical areas:

Home Diagnostic Testing

Home medical tests related to Sjogren's Syndrome:

Wrongly Diagnosed with Sjogren's Syndrome?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Sjogren's Syndrome includes:

See the full list of 22 alternative diagnoses for Sjogren's Syndrome

Sjogren's Syndrome: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

More about symptoms of Sjogren's Syndrome:

More information about symptoms of Sjogren's Syndrome and related conditions:

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

Medical Books Online about Sjogren's Syndrome

Medical Books Excerpts Excerpts of published medical book chapters related to Sjogren's Syndrome are available from published medical books for more detailed information about Sjogren's Syndrome.

Medical Books Excerpts
  • Red Eye
  • "In a Page: Signs and Symptoms" (2004)
  • RED EYE
  • "Differential Diagnosis in Primary Care" (2007)
  • Keratitis
  • "Professional Guide to Diseases (Eighth Edition)" (2005)
  • Red Eye
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Red Eye
  • "Field Guide to Bedside Diagnosis" (2007)
  • Red Eye
  • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
  • RED EYE
  • "Differential Diagnosis in Primary Care" (2007)

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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Patient Surveys for Sjogren's Syndrome

Symptoms of Sjogren's Syndrome: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of Sjogren's Syndrome.


Conjunctivitis: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Conjunctivitis commonly produces hyperemia of the conjunctiva, sometimes accompanied by discharge, tearing and, with corneal involvement, pain and photophobia. It generally doesn’t affect vision. Conjunctivitis usually begins in one eye and rapidly spreads to the other by contamination of towels, washcloths, or the patient’s own hand.

Acute bacterial conjunctivitis (pinkeye) usually lasts only 2 weeks. The patient typically complains of itching, burning, and the sensation of a foreign body in his eye. The eyelids show a crust of sticky, mucopurulent discharge. If the disorder is due to N. gonorrhoeae, however, the patient exhibits a profuse, purulent discharge.

Viral conjunctivitis produces copious tearing with minimal exudate, and enlargement of the preauricular lymph node. Some viruses follow a chronic course and produce severe disabling disease; others last 2 to 3 weeks and are self-limiting.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Inclusion conjunctivitis: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Inclusion conjunctivitis develops 5 to 12 days after contamination (it takes longer to develop than gonococcal ophthalmia). In a neonate, reddened eyelids and tearing with moderate mucoid discharge are presenting symptoms. In neonates, pseudo-membranes may form, which can lead to conjunctival scarring. In adults, follicles appear inside the lower eyelids; such follicles don’t form in infants because the lymphoid tissue isn’t yet well developed. Children and adults also develop preauricular lymphadenopathy, and children may develop otitis media as a complication. Inclusion conjunctivitis may persist for weeks or months, possibly with superficial corneal involvement.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Sjögren's syndrome: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

About 50% of patients with Sjögren’s syndrome have confirmed RA and a history of slowly developing sicca complex. However, some patients seek medical help for rapidly progressive and severe oral and ocular dryness, in many cases accompanied by periodic parotid gland enlargement. Ocular dryness (xerophthalmia) leads to foreign body sensation (gritty, sandy eye), redness, burning, photosensitivity, eye fatigue, itching, and mucoid discharge. The patient may also complain of a film across his field of vision.

Oral dryness (xerostomia) leads to difficulty swallowing and talking; abnormal taste or smell sensation or both; thirst; ulcers of the tongue, buccal mucosa, and lips (especially at the corners of the mouth); and severe dental caries. Dryness of the respiratory tract leads to epistaxis, hoarseness, chronic nonproductive cough, recurrent otitis media, and increased incidence of respiratory infections.

Other effects may include dyspareunia and pruritus (associated with vaginal dryness), generalized itching, fatigue, recurrent low-grade fever, and arthralgia or myalgia. Lymph node enlargement may be the first sign of malignant lymphoma or pseudolymphoma.

Specific extraglandular findings in Sjögren’s syndrome include interstitial pneumonitis; interstitial nephritis, which results in renal tubular acidosis in 25% of patients; Raynaud’s phenomenon (20%); and vasculitis, usually limited to the skin and characterized by palpable purpura on the legs (20%). About 50% of patients show evidence of hypothyroidism related to autoimmune thyroid disease. A few patients develop systemic necrotizing vasculitis.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Keratitis: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Keratitis is usually unilateral. The patient presents with decreased vision, discomfort ranging from mild irritation to acute pain, tearing, and photophobia. On gross examination with a penlight, the corneal light reflex may appear distorted. When keratitis results from exposure, it usually affects the lower portion of the cornea.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Conjunctivitis: Signs and symptoms
(Handbook of Diseases)

Conjunctivitis commonly produces hyperemia of the conjunctiva, sometimes accompanied by discharge and tearing. It generally doesn’t affect vision unless there is corneal involvement, which also causes pain and photophobia. Conjunctivitis usually begins in one eye and rapidly spreads to the other by contamination of towels and washcloths or by the patient’s own hands.

Acute bacterial form

With acute bacterial conjunctivitis (pinkeye), the infection usually lasts only 2 weeks. The patient typically complains of itching, burning, and the sensation of a foreign body in his eye. The eyelids show a crust of sticky, mucopurulent discharge. If the disorder stems from N. gonorrhoeae, however, the patient exhibits a profuse, purulent discharge.

Viral form

Viral conjunctivitis produces copious tearing with minimal exudate and enlargement of the preauricular lymph node. Some viruses follow a chronic course and produce severe disabling disease; others last 2 to 3 weeks.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Inclusion conjunctivitis: Signs and symptoms
(Handbook of Diseases)

Inclusion conjunctivitis develops 5 to 10 days after contamination (it takes longer to develop than gonococcal ophthalmia). In neonates, the lower eyelids redden and a thick, purulent discharge develops. In children and adults, follicles appear inside the lower eyelids; such follicles don’t form in infants because the lymphoid tissue isn’t yet well developed. Children and adults also develop preauricular lymphadenopathy and — as complications, otitis media and, occasionally, interstitial pneumonia.

Inclusion conjunctivitis may persist for weeks or months, possibly with superficial corneal involvement. In neonates, pseudomembranes may form, which can lead to conjunctival scarring.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Sjögren's syndrome: Signs and symptoms
(Handbook of Diseases)

About 50% of patients with SS have confirmed RA and a history of slowly developing sicca complex. However, some seek medical help for rapidly progressive and severe oral and ocular dryness, often accompanied by periodic parotid gland enlargement.

Ocular effects

Ocular dryness (xerophthalmia) leads to foreign body sensation (gritty, sandy eye), redness, burning, photosensitivity, eye fatigue, itching, and mucoid discharge. The patient may also complain of a film across his field of vision.

Oral effects

Oral dryness (xerostomia) leads to difficulty swallowing and talking; abnormal taste or smell sensation, or both; thirst; ulcers of the tongue, buccal mucosa, and lips (especially at the corners of the mouth); and severe dental caries. Dryness of the respiratory tract leads to epistaxis, hoarseness, chronic nonproductive cough, recurrent otitis media, and increased incidence of respiratory infections.

Other features

Other effects may include dyspareunia and pruritus (associated with vaginal dryness), generalized itching, fatigue, recurrent low-grade fever, and arthralgia or myalgia.

CLINICAL TIP: Lymphadenopathy is relatively common in patients with SS, but persistent, firm lymph node enlargement may be the first sign of malignant transformation. Patients with primary SS have a 44 times greater relative risk of lymphoma than does the general population.

Specific extraglandular findings in SS include interstitial pneumonitis; interstitial nephritis, which can result in renal tubular acidosis; Raynaud’s phenomenon; arthritis and arthralgias; peripheral neuropathy; and vasculitis, usually limited to the skin and characterized by palpable purpura on the legs.

About 50% of patients show evidence of hypothyroidism related to autoimmune thyroid disease. A few patients develop systemic necrotizing vasculitis.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Keratitis: Signs and symptoms
(Handbook of Diseases)

Unilateral keratitis may produce pain, tearing, and photophobia. If the infection is in the center of the cornea, it may produce blurred vision. Left untreated, corneal opacities can occur. When keratitis results from exposure, it usually affects the lower portion of the cornea.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Article Excerpts About Symptoms of Sjogren's Syndrome:

NINDS Sjogren's Syndrome Information Page: NINDS (Excerpt)

The hallmark symptoms of the disorder are dry mouth and dry eyes. In addition, Sjogren's syndrome may cause skin, nose, and vaginal dryness, and may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain. (Source: excerpt from NINDS Sjogren's Syndrome Information Page: NINDS)

Questions and Answers About Sjögren's Syndrome: NIAMS (Excerpt)

In technical terms, dry eyes are called keratoconjunctivitis sicca, or KCS, and dry mouth is called xerostomia. Your doctor may use these terms when talking to you about Sjögren's syndrome.

The disease can affect other glands too, such as those in the stomach, pancreas, and intestines, and can cause dryness in other places that need moisture, such as the nose, throat, airways, and skin. (Source: excerpt from Questions and Answers About Sjögren's Syndrome: NIAMS)

Questions and Answers About Sjögren's Syndrome: NIAMS (Excerpt)

The main symptoms are

  • Dry eyes--Your eyes may be red and burn and itch. People say it feels like they have sand in their eyes. Also, your vision may be blurry, and bright light, especially fluorescent lighting, might bother you.

  • Dry mouth--Dry mouth feels like a mouth full of cotton. It's difficult to swallow, speak, and taste. Your sense of smell can change, and you may develop a dry cough. Also, because you lack the protective effects of saliva, dry mouth increases your chances of developing cavities and mouth infections.

Both primary and secondary Sjögren's syndrome can affect other parts of the body as well, including the skin, joints, lungs, kidneys, blood vessels, and nervous system, and cause symptoms such as

  • Dry skin

  • Skin rashes

  • Thyroid problems

  • Joint and muscle pain

  • Pneumonia

  • Vaginal dryness

  • Numbness and tingling in the extremities

When Sjögren's affects other parts of the body, the condition is called extraglandular involvement because the problems extend beyond the tear and salivary glands. These problems are described in more detail later.

Finally, Sjögren's can cause extreme fatigue that can seriously interfere with daily life. (Source: excerpt from Questions and Answers About Sjögren's Syndrome: NIAMS)

Connective Tissue Diseases: NWHIC (Excerpt)

Dryness of the eyes and mouth, swollen neck glands, difficulty swallowing or talking, unusual tastes or smells, thirst, tongue ulcers, and severe dental caries. (Source: excerpt from Connective Tissue Diseases: NWHIC)

Sjogren's Syndrome as a Cause of Symptoms or Medical Conditions

When considering symptoms of Sjogren's Syndrome, it is also important to consider Sjogren's Syndrome as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Sjogren's Syndrome may cause:

- (Source - Diseases Database)

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

Full list of premium articles on symptoms and diagnosis

About signs and symptoms of Sjogren's Syndrome:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Sjogren's Syndrome. This signs and symptoms information for Sjogren's Syndrome has been gathered from various sources, may not be fully accurate, and may not be the full list of Sjogren's Syndrome signs or Sjogren's Syndrome symptoms. Furthermore, signs and symptoms of Sjogren's Syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Sjogren's Syndrome symptoms.


 » Next page: Diagnostic Tests for Sjogren's Syndrome

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