Clinical Trials for Sleep deprivation

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Sleep deprivation is grouped into the following categories:-

• View by trial name
• View by drugs used in Sleep deprivation clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Sleep deprivation:

• Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation - This study has been completed (Current: 23 Nov 2006) - Controlled Dietary Intervention
• Comparing Tai Chi Training to a Low-Stress Physical Activity to Enhance Sleep in Older Adults - This study has been completed (Current: 23 Nov 2006)
• Effects of Sleep Deprivation and Recovery on Cognitive Functions - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tips for Infant and Parent Sleep (TIPS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents - This study has been completed (Current: 23 Nov 2006)
• Behavioral and Pharmacological Treatment for Insomnia - This study has been completed (Current: 23 Nov 2006) - zolpidem
• Combined Behavioral/Pharmacological Therapy for Insomnia - This study is currently recruiting patients (Current: 23 Nov 2006) - zolpidem tartrate (Ambien)
• Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG - This study has been completed (Current: 23 Nov 2006)
• Yohimbine to Induce Rapid Antidepressant Effects - This study is currently recruiting patients (Current: 23 Nov 2006) - Yohimbine,Yohimbine hydrochloride
• Chronos: the Use of Chronobiological Treatment in Depression - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effects of Sleep Deprivation on Antidepressant Response - This study has been completed (Current: 23 Nov 2006)
• Protecting Health In Later Life - This study has been completed (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Sleep deprivation

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Sleep deprivation:

• Controlled Dietary Intervention - A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation - This study has been completed (Current: 23 Nov 2006)
• Yohimbine hydrochloride - Yohimbine to Induce Rapid Antidepressant Effects - This study is currently recruiting patients (Current: 23 Nov 2006)
• Yohimbine - Yohimbine to Induce Rapid Antidepressant Effects - This study is currently recruiting patients (Current: 23 Nov 2006)
• Zolpidem Tartrate (Ambien) - Combined Behavioral/Pharmacological Therapy for Insomnia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Zolpidem - Behavioral and Pharmacological Treatment for Insomnia - This study has been completed (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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