Prevalence and Incidence of Soto's Syndrome
Prevalance of Soto's Syndrome:
rare ... see also overview of Soto's Syndrome.
Soto's Syndrome: Rare Disease
Soto's Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Soto's Syndrome, or a subtype of Soto's Syndrome,
affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Soto's Syndrome as a "rare disease".
More information about Soto's Syndrome is available from Orphanet
Soto's Syndrome Prevalence: Book Excerpts
Incidence (annual) of Soto's Syndrome:
estimated 1 per 5,000 newborns have Sotos syndrome which includes reported cases and undiagnosed cases, Genetics Home Reference website ... see also overview of Soto's Syndrome.
Incidence Rate:
approx 1 in 5,000 or 0.02% or 54,400 people in USA [Source statistic for calcuation: "estimated 1 per 5,000 newborns have Sotos syndrome which includes reported cases and undiagnosed cases, Genetics Home Reference website" -- see also general information about data sources]
Incidence extrapolations for USA for Soto's Syndrome:
54,399 per year,
4,533 per month,
1,046 per week,
149 per day,
6 per hour,
0 per minute,
0 per second.
[Source statistic for calculation: "estimated 1 per 5,000 newborns have Sotos syndrome which includes reported cases and undiagnosed cases, Genetics Home Reference website" -- see also general information about data sources]
Prevalence/Incidence of Soto's Syndrome: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Soto's Syndrome.
Acromegaly and gigantism:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Typically, oversecretion of human growth hormone (hGH) produces changes throughout the body, resulting in acromegaly and, when oversecretion occurs before puberty, gigantism. Eosinophilic or mixed-cell adenomas of the anterior pituitary gland may cause this oversecretion but the etiology of the tumors themselves remains unclear. Occasionally, hGH levels are elevated in more than one family member, which suggests the possibility of a genetic cause.
The earliest clinical manifestations of acromegaly include soft-tissue swelling of the extremities and coarsening of facial features. This rare form of hyperpituitarism occurs equally among males and females, usually between ages 30 and 50. Annually, it affects 3 to 4 people per every million.
In gigantism, proportional overgrowth of all body tissues starts before epiphyseal closure. This causes remarkable height increases of as much as 6"(15 cm) per year. Gigantism affects infants and children, causing them to attain as much as three times the normal height for their age. As adults, they may ultimately reach a height of more than 80"(203 cm). Gigantism is rare; there have only been 100 reported cases.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Developmental Disabilities:
Developmental Disabilities - epidemiology
(The 5-Minute Pediatric Consult)
Found in both sexes and all racial and socioeconomic groups.
Developmental Disabilities - prevalence
This is a heterogeneous group of disorders with different prevalence rates.
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Soto's Syndrome usually refers to the estimated population
of people who are managing Soto's Syndrome at any given time.
The term 'incidence' of Soto's Syndrome refers to the annual diagnosis rate,
or the number of new cases of Soto's Syndrome diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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