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Glossary for Stevens-Johnson Syndrome

  • Amobarbital - Teratogenic Agent: There is strong evidence to indicate that exposure to Amobarbital during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Benign mucosal pemphigoid: A rare chronic disease involving blistering and scarring of the mucous membranes especially in the mouth and conjunctiva of the eye.
  • Blisters: Blistering of the skin.
  • Bullous Pemphigoid: A chronic skin disorder characterized blistering of the skin which usually occurs on the joints, abdomen, armpit and groin areas.
  • Chickenpox: Common viral infection.
  • Conjunctivitis: Contagious eye infection
  • Contact dermatitis: Skin reaction to an irritant
  • Cornea disorders: Disorders affecting the cornea of the eye
  • Cornea/lens symptoms: Symptoms affecting the cornea or lens of the eye
  • Corneal scarring: Scarring occurring on the cornea.
  • Corneal ulceration: Ulceration of the corneal epithelium.
  • Death: The cessation of life
  • Dermatitis herpetiformis: Blistering skin rash of elbows, knees, and buttocks.
  • Dry Eye: Dry eyes or gritty eye feeling.
  • Eosinophilia: This is when there is an abnormal increase in the eosinophils in the blood
  • Epidermolysis bullosa: A group of rare inherited skin diseases characterized by fragile skin which forms blisters with even minor injuries. The blisters can be painful and can occur anywhere on the skin and even inside the digestive tract.
  • Erythema: A condition which is characterized by redness of the skin due to congestion of the capillaries
  • Erythema multiforme: An allergic inflammatory skin disorder which has a variety of causes and results in skin and mucous membrane lesions that affect mainly the hands, forearms, feet, mouth nose and genitals.
  • Esophageal stricture: Narrowing of the esophagus
  • Eye conditions: Any condition that affects the eyes
  • Gestational pemphigoid: A rare autoimmune skin blistering disorder that occurs during pregnancy onset during second trimester with severe form recurring after delivery during menstruation.
  • Graft-versus-host disease: A disease characterised by an immune response as a result of a transplantation or transfusion resulting in a widespread systemic inflammatory response
  • Histoplasmosis: Lung infection from fungus Histoplasma capsulatum
  • Iritis: Inflammation of the iris and anterior chamber of the eye.
  • Keratitis: Any inflammation of the cornea of the eye
  • Linear IgA dermatosis: A rare autoimmune skin condition characterized by blistered skin. The condition may occur after using certain drugs, following infection or there may be no apparent cause. It tends to occur in the non-reproductive years and most often affects the limbs, face or genital regions but may occur anywhere. The blisters may occur separately, in clusters or various other formations.
  • Loss of vision: The loss of ones ability to see
  • Mouth redness: Redness or red spots in the mouth
  • Mouth ulcers: Ulcers in the mouth membranes or oral areas
  • Mucous membrane lesions: lesions affecting the mucosa of the oral cavity.
  • Mycoplasma pneumoniae: Bacterial respiratory infection
  • Panophthalmitis: An inflammation of the inner eye which usually affects all the layers of the eyeball. The inflammation can also extend into tissue surrounding the eyeball. The infection can result from a penetrating injury to the eye, septicemia or can spread from pus-producing infection in another part of the body.
  • Pemphigus: A rare group of autoimmune skin disorders where blisters or raw sores develop on the skin and mucous membranes. The bodies immune system destroys proteins the hold skin cells together resulting in blistering. The condition can be life-threatening if untreated.
  • Pemphigus Foliaceus: A relatively milder form of the autoimmune skin disorder called pemphigus. Blisters occur on the skin but usually the mucous membranes are unaffected.
  • Porphyria Cutanea Tarda: A rare metabolic condition involving a deficiency of the enzyme uroporphyrinogen decarboxylase. This results in a buildup of porphyrins in the skin which makes it sensitive to light. Most symptoms tend to primarily affected the areas of skin most exposed to sun e.g. back of hands and arms.
  • Red throat: Redness inside the throat
  • Schwartz-Jampel Syndrome: A rare genetic disorder characterized by myotonia, blepharophimosis and joint limitation.
  • Skin conditions: Any condition that affects the skin
  • Skin lesion: Lesions appearing on the skin.
  • Toxic Shock Syndrome: Severe immune reaction causing shock
  • Toxic epidermal necrolysis: A skin condition causing widespread blisters to erupt over greater than 30% of the body.


 » Next page: Clinical Trials for Stevens-Johnson Syndrome

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