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Stiff-Person Syndrome
Stiff-Person Syndrome: Introduction
A very rare autoimmune disorder of the central nervous system causing various symptoms, but also sometimes diabetes. The patient usually has anti-GAD antibodies, and about half get a type of secondary diabetes from SMS.
Symptoms of Stiff-Person Syndrome
- Constant painful contractions
- Muscle spasms - esp. back and upper legs but sometimes the arms and neck.
- Worsening with anxiety
- Worsening with sudden motion
- Worsening with sudden noise
- more symptoms...»
See full list of 22 symptoms of Stiff-Person Syndrome
Stiff-Person Syndrome: Complications
Review possible medical complications related to Stiff-Person Syndrome:
Medical Textbooks Online about Stiff-Person Syndrome
Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
Wrongly Diagnosed with Stiff-Person Syndrome?
Causes of Stiff-Person Syndrome
Read more about causes of Stiff-Person Syndrome.
Treatments for Stiff-Person Syndrome
See full list of 7 treatments for Stiff-Person Syndrome
News Archives for Stiff-Person Syndrome
Medical news articles related to Stiff-Person Syndrome include:
- What's That Smell? Ask a Woman, Not a Man
- Thinking Man's Chimp Shows 1st Animal 'Planning'
- 'Blind' Man Navigates Obstacle Course Without Error
- Health Tip: When Another Person Bites You
- Health Tip: Talking to a Person With Alzheimer's Disease
- Personal Contact Helps Maintain Weight Loss
- more health news...»
Source: HealthDay News
Evidence Based Medicine Research for Stiff-Person Syndrome
Medical research articles related to Stiff-Person Syndrome include:
- Paraneoplastic Syndromes (Overview)
- Paraneoplastic Syndromes (Treatment)
- Stiff Person Syndrome (Overview)
- Stiff Person Syndrome (Follow-up)
- Paraneoplastic Syndromes (Diagnosis)
- Paraneoplastic Syndromes (Follow-up)
- Stiff Person Syndrome (Treatment)
- Stiff Person Syndrome (Diagnosis)
- more research...»
Click here to find more evidence-based articles on the TRIP Database
Videos for Stiff-Person Syndrome
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Medications for Parkinson's disease work very well. But symptoms can creep back when they wear off. Discover how one patient is trying to keep...
Patient Surveys for Stiff-Person Syndrome
- Patient Profile Survey
Take Survey View Results - Survey about the symptoms of your Stiff-Person Syndrome
Take Survey View Results
Prognosis for Stiff-Person Syndrome
Prognosis for Stiff-Person Syndrome: There is no cure for stiff-person syndrome. The long-term prognosis for individuals with stiff-person syndrome is uncertain. Management of the disorder with drug therapy may provide significant improvements and relief of symptoms. (Source: excerpt from NINDS Stiff-Person Syndrome Information Page: NINDS)
More about prognosis of Stiff-Person Syndrome
Reseach about Stiff-Person Syndrome
Visit our research pages for current research about Stiff-Person Syndrome treatments.
Clinical Trials for Stiff-Person Syndrome
The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.
Some of the clinical trials listed on ClinicalTrials.gov for Stiff-Person Syndrome include:
- Cause, Development, and Progression of Stiff-Person Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Rituximab to Treat Stiff Person Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab
- Intravenous Immunoglobulin (IVIg) for the Treatment of Stiff-Man Syndrome (SMS) - This study has been completed (Current: 23 Nov 2006)
- more trials...»
Read more about Clinical Trials for Stiff-Person Syndrome
Statistics for Stiff-Person Syndrome
- Medical statistics for Stiff-Person Syndrome
- Prevalence and incidence statistics for Stiff-Person Syndrome
- Death and Mortality statistics for Stiff-Person Syndrome
- Society statistics for Stiff-Person Syndrome
Stiff-Person Syndrome: Broader Related Topics
- Possibly autoimmune diseases
- more types...»
Types of Stiff-Person Syndrome
Stories from Users Related to Stiff-Person Syndrome
- 2 Personalities?!
- Border Personality Disorder or/and Asperger's Syndrome???
- Stiff-Person Syndrome
- Man Boobs?
- So weird. Must be the only person the planet with this lol
- personality disorder
- Stiff Person's Syndrome
- Yes, Please Help an Old Man
- Not a Morning Person
- The Personality Disorder debate...
- stiff mans syndrome
- double sex in one person
- help split personality disorder?
- Schitzoid personality disorder?
- Gonorrhea/Chlymedia (sp?) question
- Not a happy person
- Scared stiff everytime! It's scares me alot!
- Bit of a personal one...
- scared stiff
Related forums and medical stories:
User Interactive Forums
Read about other experiences, ask a question about Stiff-Person Syndrome, or answer someone else's question, on our message boards:
- I can not get a diagnosis. Please help.
- Tell us your medical story.
- Share your misdiagnosis story.
- What is the best treatment for this?
- See all the forums.
Article Excerpts about Stiff-Person Syndrome
Stiff-person syndrome is a rare progressive neurological disorder characterized by constant painful contractions and spasms of voluntary muscles, particularly the muscles of the back and upper legs. (Source: excerpt from NINDS Stiff-Person Syndrome Information Page: NINDS)
Definitions of Stiff-Person Syndrome:
A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93) - (Source - Diseases Database)
Stiff-Person Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Stiff-Person Syndrome, or a subtype of Stiff-Person Syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Stiff-Person Syndrome as a "rare disease".
Source - Orphanet
- Stiff-Person Syndrome
- What is Stiff-Person Syndrome?
- Online Medical Textbooks for Stiff-Person Syndrome
- Prevalence and Incidence of Stiff-Person Syndrome
- Videos related to Stiff-Person Syndrome
- Prognosis of Stiff-Person Syndrome
- Causes of Stiff-Person Syndrome
- Risk Factors for Stiff-Person Syndrome
- Symptoms of Stiff-Person Syndrome
- Diagnosis of Stiff-Person Syndrome
- Signs of Stiff-Person Syndrome
- Complications of Stiff-Person Syndrome
- Undiagnosed Stiff-Person Syndrome
- Associated Conditions of Stiff-Person Syndrome
- Treatments for Stiff-Person Syndrome
- Cure Research for Stiff-Person Syndrome
- Statistics about Stiff-Person Syndrome
- Statistics by Country for Stiff-Person Syndrome
- Medical News Summaries About Stiff-Person Syndrome
- Articles about Stiff-Person Syndrome
- Glossary for Stiff-Person Syndrome
- Clinical Trials for Stiff-Person Syndrome
- External links relating to Stiff-Person Syndrome
- Personality disorders (Professional Guide to Diseases (Eighth Edition))
- Personality disorders (Handbook of Diseases)
» Next page: What is Stiff-Person Syndrome?
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- Prevalence and Incidence of Stiff-Person Syndrome
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