As with all medical conditions, there may be many causal factors. Further relevant information on causes of Strongyloidiasis may be found in:
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Transmission to humans usually occurs through contact with soil that contains infective S. stercoralis filariform larvae; such larvae develop from noninfective rhabdoid (rod-shaped) larvae in human feces. The filariform larvae penetrate the human skin, usually at the feet. They migrate by way of the lymphatic system to the bloodstream and the lungs.
Once they enter into pulmonary circulation, the filariform larvae break through the alveoli and migrate upward to the pharynx, where they are swallowed. They then lodge in the small intestine, where they deposit eggs that mature into noninfectious rhabdoid larvae. Next, these larvae migrate into the large intestine and are excreted in feces, starting the cycle again. The threadworm life cycle, which begins with penetration of the skin and ends with excretion of rhabdoid larvae, takes 17 days.
In autoinfection, rhabdoid larvae mature within the intestine to become infective filariform larvae.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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