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What is the WBC count? Thrombocytopenia with a high white count suggests leukemia or myeloid metaplasia. Thrombocytopenia with a normal white count suggests ... DIAGNOSTIC WORKUP
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Is there a petechial rash? The presence of a petechial rash suggests either a thrombocytopenic purpura, which may be idiopathic or secondary to leukemia, aplastic anemia, collagen disease, or ... DIAGNOSTIC WORKUP
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Because the differential diagnosis of purpura is very large, begin by determining whether the purpura is palpable or nonpalpable. Subsequent workup is dictated by the history, physical, and review of systems to determine appropriate... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Purpura represents leakage of blood from vessels into skin/mucous membranes; thus, it is nonblanching on pressure; petechiae are <3 mm, ecchymosis >3 mm in diameter. Idiopathic>... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Thrombocytopenia is defined as a platelet count of <150,000. Mild (100,000–150,000) and moderate (50,000–100,000) thrombocytopenia are rarely associated with significant bleeding. In contrast to the deep muscle>... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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... The mnemonic VINDICATE is very useful to develop a list of causes of thrombocytopenia.
THROMBOCYTOPENIA
V—Vascular
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... Purpura is the extravasation of red blood cells from the blood vessels into the skin, subcutaneous tissue, or mucous membranes. It’s characterized by discoloration that’s... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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... Decreased Production
Primary hematologic disorders
Aplastic anemia
Acute leukemia
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... Platelet Disorders
Thrombocytopenia
Drugs, especially
Cytotoxic
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... Hemophilia is a hereditary bleeding disorder resulting from a deficiency of specific clotting factors. After a person with hemophilia forms a platelet plug at a bleeding site, the clotting factor deficiency impairs the blood's capacity to... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... The most common cause of hemorrhagic disorders, thrombocytopenia is characterized by deficiency of circulating platelets. Because platelets play a vital role in coagulation, this disease poses a serious threat to... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Platelet function disorders are similar to thrombocytopenia but result from platelet dysfunction rather than platelet deficiency. They characteristically cause defects in platelet adhesion or procoagulation... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Allergic purpura, a nonthrombocytopenic purpura, is an acute or chronic vascular inflammation affecting the skin, joints, and GI and genitourinary (GU) tracts, in association with... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Idiopathic thrombocytopenic purpura (ITP), thrombocytopenia that results from immunologic platelet destruction, may be acute (postviral thrombocytopenia) or chronic (Werlhof’s disease, purpura hemorrhagica, essential... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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Purpura
(Professional Guide to Signs & Symptoms (Fifth Edition))
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... Purpura is the extravasation of red blood cells from the blood vessels into the skin, subcutaneous tissue, or mucous membranes. It’s characterized by discoloration that’s easily... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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Thrombocytopenia
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)
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... Mark D. Darrow
A low platelet count is usually brought to the attention of the practitioner as the result of an automated complete blood count in an asymptomatic patient (1).
I.... Pictures
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Petechiae and Purpura
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)
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... John L. Smith
Purpura are the visible extravasation of blood into the skin or mucous membranes. Petechiae are purpura less than 2 mm in diameter and... Approach ... History ... Physical examination ... Testing ... Diagnostic assessment (4)
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... Differential Overview
Purpura
❑Trauma
❑Senile purpura
❑Drugs ... Diagnostic Approach ... Clinical Findings ... Pictures
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... A hereditary bleeding disorder, hemophilia results from the deficiency of specific clotting factors. Hemophilia A (classic hemophilia), which affects more than 80% of all hemophiliacs, results... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... The most common cause of hemorrhagic disorders, thrombocytopenia is characterized by deficiency of circulating platelets. Because platelets play a vital role in coagulation, this... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Allergic purpura, or anaphylactoid purpura, is a type of nonthrombocytopenic purpura. It’s characterized by allergy symptoms and acute or chronic vascular inflammation affecting the skin, joints, or GI or... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Idiopathic thrombocytopenic purpura (ITP), thrombocytopenia that results from immunologic platelet destruction, may be acute (postviral thrombocytopenia) or chronic (Werlhof’s disease, purpura hemorrhagica, essential... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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Purpura
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
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... Purpura is the extravasation of red blood cells from the blood vessels into the skin, subcutaneous tissue, or mucous membranes. It’s characterized by discoloration that’s easily... History ... Physical assessment ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Patient counseling ... Pictures
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...Purpura are macular discolorations that donot blanch or disappear with pressure. They include petechiae (<3mm in diameter) and ecchymoses (larger lesions). Principal Causes of Purpura> ... Clinical Features and Diagnosis ... Diagnostic Approach ... References
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... Purpura is the extravasation of red blood cells from the blood vessels into the skin, subcutaneous tissue, or mucous membranes. It's characterized by discoloration that's easily visible... History and physical examination ... Medical causes ... Other causes ... Nursing considerations ... Patient teaching ... Pictures
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The mnemonic VINDICATE is very useful to develop a list of
causes of thrombocytopenia.
V—Vascular disorders should help
the recall of disseminated intravascular coagulation (DIC).
I&... Pictures
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