Diagnostic Tests for Dark skin

Diagnostic Test list for Dark skin:

The list of diagnostic tests mentioned in various sources as used in the diagnosis of Dark skin includes:

• Physical examination
  • Examine the dark skin in area or areas affected and note pigmentation features
  • Examine for signs of systemic disease that may be associated with the casue of the dark skin - e.g. enlarged liver with jaundice.
• Blood tests
  • Full blood count
  • ESR
  • Liver function tests - can diagnose jaundice and liver inflammation due to hemochromatosis.
  • Electrolytes and kidney function tests - high potassium in Addison's disease; elevated calcium in sarcoidosis.
  • Iron studies - raised ferritin and transferring saturation in hemochromatosis.
  • Cortisol, ACTH assay, Synacthen stimulation test, adrenal antibodies - if suspect Addison's disease.
  • Antinuclear, antinucleolar and anticentromere antibodies - may be elevated in systemic sclerosis.
  • HIV serology - if suspect Kaposi's sarcoma.
  • Hepatitis serology - if jaundice is diagnosed.
• Skin biopsy of localized dark skin lesion - to assist diagnosis.
• Liver biopsy - if suspect hemochromatosis.
• Radiological investigations
• Chest X-Ray if suspect sarcoidosis
• Transbronchial biopsy - may be required if suspect sarcoidosis.

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