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Is there jaundice? Hepatomegaly with jaundice may make one think of hemolytic anemias; toxic or infectious hepatitis; bile duct obstruction due to stones, carcinoma of the ... DIAGNOSTIC WORKUP
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Is the jaundice associated with hepatomegaly? There is little or no hepatomegaly associated with hemolytic anemias, pernicious anemia, Gilbert's disease, and ... DIAGNOSTIC WORKUP
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Hepatomegaly, or enlargement of the liver, usually refers to a liver span of larger than 12 cm at the right midclavicular line or a palpable left lobe in the epigastrium. However, liver size... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Yellow skin pigmentation caused by elevated serum bilirubin level is termed jaundice. Bilirubin is the major breakdown product of hemoglobin that is released from dying or damaged erythrocytes. The normal serum bilirubin is... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Hepatomegaly represents the clinical appearance of liver enlargement and can occur via five mechanisms, including inflammation, excessive storage, infiltration, congestion, and... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Jaundice refers to the presence of a yellow hue of the skin, sclerae, or mucous membranes. Direct, or more specifically, conjugated hyperbilirubinemia represents a pathologic condition of cholestasis. It is defined... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Jaundice is the presence of a yellow hue of the skin, sclerae, or mucous membranes due to elevation of serum bilirubin; it usually becomes apparent at a total serum bilirubin level of 5 mg/dL. It is... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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... Two key words to think of here are histology and obstruction. The analysis of the differential diagnosis of hepatomegaly is best begun with a histologic breakdown of the liver tissue ( Table 37
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... Jaundice is not to be confused with xanthochromia, in which the skin turns orange from carotene deposits but the sclerae remain normal in appearance. Carotenemia is often seen in hypothyroidism and diabetes mellitus, but
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... Hepatomegaly, an enlarged liver, indicates potentially reversible primary or secondary liver disease This sign may stem from diverse pathophysiologic mechanisms, including dilated... History and physical examination ... Medical causes ... Special considerations ... Pictures
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...Icterus
A yellow discoloration of the skin, mucous membranes, or sclera of the eyes, jaundice indicates excessive levels of conjugated or unconjugated bilirubin in the... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Pictures
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... A bilateral, coarse movement, asterixis is characterized by sudden relaxation of muscle groups holding a sustained posture. This elicited sign is most commonly observed in the wrists... Emergency interventions ... Medical causes ... Other causes ... Special considerations
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... Palpable Liver without Hepatic Pathology
Normal variant
Thin or flaccid abdominal wall
Depressed right diaphragm (e.g., emphysema)
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... Primarily Unconjugated Hyperbilirubinemia
Increased production
Hemolysis, intravascular or extravascular
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... Alcoholic
Infectious
Viral hepatitis (especially B and C)
Schistosomiasis
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... Fatty liver, also known as steatosis, is a common clinical finding consisting of accumulated triglycerides and other fats in liver cells. In severe fatty liver, fat comprises as much as 40% of the liver’s weight (as... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... A liver abscess occurs when bacteria or protozoa destroy hepatic tissue, producing a cavity, which fills with infectious organisms, liquefied liver cells, and leukocytes. Necrotic tissue then... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Liver cancer, also known as primary and metastatic hepatic carcinoma, is a rare form of cancer in the United States, with a high mortality. Most primary liver tumors (90%) originate in the parenchymal cells... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Hepatomegaly, an enlarged liver, indicates potentially reversible primary or secondary liver disease. This sign may stem from diverse pathophysiologic mechanisms, including dilated hepatic sinusoids (in heart failure),... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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... A bilateral, coarse movement, asterixis is characterized by sudden relaxation of muscle groups holding a sustained posture. This elicited sign is most commonly observed in the wrists and fingers but may also appear during any sustained... Emergency interventions ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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... A yellow discoloration of the skin, mucous membranes, or sclera of the eyes, jaundice indicates excessive levels of conjugated or unconjugated bilirubin in the blood. In fair-skinned patients, it’s most noticeable on the face,... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Patient counseling ... Pictures
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Hepatomegaly
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)
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... Darryl G. White and Bruce A. Leibert
Approach Hepatomegaly is a physical sign noted on abdominal examination that is present in hepatobiliary disease but is not specific or... History ... Physical examination ... Testing ... Diagnostic assessment ... Summary ... Pictures
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Jaundice
(The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter)
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... James M. Brian and Cara K. Fox
The hepatobiliary system removes bilirubin, a byproduct of hemoglobin metabolism, from the blood stream. Jaundice, a yellowing of the skin and sclera, results from tissue build... Approach ... History ... Physical examination ... Testing ... Diagnostic assessment ... Pictures
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... Differential Overview
❑ Acute hepatitis
❑ Chronic hepatitis
❑ Cirrhosis
❑ Right... Diagnostic Approach ... Clinical Findings ... Pictures
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... Differential Overview
Conjugated
❑ Viral hepatitis
❑ Gallstone obstruction
❑ Drugs
❑... Diagnostic Approach ... Clinical Findings ... Pictures
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... Steatosis, or fatty liver, is the accumulation of triglycerides and other fats in liver cells. In severe fatty liver, fat constitutes as much as 40% of the liver’s weight (as opposed to... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... A liver abscess occurs when bacteria or protozoa destroy hepatic tissue, producing a cavity, which fills with infectious organisms, liquefied liver cells, and leukocytes. Necrotic tissue then walls off the cavity from the rest... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... A rare form of cancer, liver cancer (primary and metastatic hepatic carcinoma) has a high mortality. It’s responsible for roughly 2% of all cancers in the United States and for 10%... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Hepatomegaly (an enlarged liver) indicates potentially reversible primary or secondary liver disease. This sign may stem from diverse pathophysiologic mechanisms, including dilated hepatic sinusoids (in heart failure), persistently... History ... Physical assessment ... Medical causes ... Special considerations ... Pediatric pointers ... Patient counseling ... Pictures
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... A yellow discoloration of the skin, mucous membranes, or sclerae of the eyes, jaundice indicates excessive levels of conjugated or unconjugated bilirubin in the blood. Also known as icterus, jaundice is most... History ... Physical assessment ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Geriatric pointers ... Patient counseling ... Pictures
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Hepatomegaly
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)
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... Liver sizemay be estimated by degree of extension of liver edge below costalmargin or by span of liver dullness to percussion. In children liver edge may be normallypalpable up to... Principal Causes of Hepatomegaly ... Clinical Features and Diagnosis ... Diagnostic Approach ... References
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Jaundice
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)
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... Jaundice,yellow discoloration of skin and sclera, is produced by depositionof bilirubin in these tissues. Increase in unconjugated or conjugatedbilirubin or both produce jaundice, which is visible when... Principal Causes of Unconjugated Hyperbilirubinemia ... Clinical Features and Diagnosis: Unconjugated Hyperbilirubinemia(Neonatal Onset) ... Clinical Features and Diagnosis: Unconjugated Hyperbilirubinemia(Postneonatal Onset) ... Diagnostic Approach: Unconjugated Hyperbilirubinemia ... Principal Causes of Conjugated Hyperbilirubinemia (NeonatalOnset) ... Clinical Features and Diagnosis: Conjugated Hyperbilirubinemia(Neonatal Onset) ... Principal Causes of Conjugated Hyperbilirubinemia (PostneonatalOnset) ... Clinical Features and Diagnosis: Conjugated Hyperbilirubinemia(Postneonatal Onset) ... Diagnostic Approach: Conjugated Hyperbilirubinemia ... References
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... Hepatomegaly, an enlarged liver, indicates potentially reversible primary or secondary liver disease. This sign may stem from diverse pathophysiologic mechanisms, including dilated hepatic sinusoids (in heart... History and physical examination ... Medical causes ... Nursing considerations ... Patient teaching ... Pictures
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... A bilateral, coarse movement, asterixis is characterized by sudden relaxation of muscle groups holding a sustained posture. This elicited sign is most commonly observed in the wrists and fingers, but may also appear during any sustained... History and physical examination ... Medical causes ... Other causes ... Nursing considerations ... Patient teaching ... Pictures
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... A yellow discoloration of the skin, mucous membranes, or sclera of the eyes, jaundice indicates excessive levels of conjugated or unconjugated bilirubin in the blood. In fair-skinned patients, it's most noticeable on... History and physical examination ... Medical causes ... Other causes ... Nursing considerations ... Patient teaching ... Pictures
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Two key words to think of here are histology and
obstruction. The analysis of the differential diagnosis of hepatomegaly is
best begun with a... Pictures
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...
Jaundice is not to be confused with xanthochromia, in which the skin
turns orange from carotene deposits but the sclerae remain normal in
appearance. Carotenemia is often seen in hypothyroidism... Pictures
... READ MEDICAL BOOK EXCERPTS ONLINE » (free access, no registration)
