EPISTAXIS
The differential diagnostic approach to epistaxis is anatomic and histologic. Table 27 breaks the nasal passages into anatomic and histologic components and cross-indexes them with the various etiologies.

EPISTAXIS
TABLE 27. EPISTAXIS
| |
V |
I |
N |
D |
I |
C |
A |
T |
E |
| |
Vascular |
Inflammation |
Neoplasm |
Deficiency |
Intoxication |
Collagen or Congenital |
Allergic and Autoimmune |
Trauma |
Endocrine |
Anterior Septal Mucosa |
|
Rhinitis |
Carcinoma (rarely) |
|
|
|
Midline granuloma and polyps |
Nose-picking |
Menopause |
| |
|
Syphilis |
|
|
|
|
Rhinitis |
Foreign body |
Menstruation |
| |
|
Leprosy |
|
|
|
|
|
|
|
| |
|
Mucormycosis |
|
|
|
|
|
|
|
| |
|
Tuberculosis |
|
|
|
|
|
|
|
Sinuses |
|
Tuberculosis |
Polyp |
|
|
|
Midline granuloma and polyps |
|
|
| |
|
Mucormycosis |
Carcinoma |
|
|
|
Sinusitis |
|
|
| |
|
Viral sinusitis |
|
|
|
|
|
|
|
Nasopharynx |
|
|
Schmincke tumor |
|
|
|
Rheumatic fever |
Skull fracture |
|
| |
|
|
Adenoid |
|
|
|
|
Foreign body |
|
Veins and Capillaries |
Venous obstruction from emphysema, asthma, and congestive heart failure |
|
Hemangioma |
|
|
Kiesselbach plexus |
|
|
|
| |
|
|
|
|
|
Telangiectasis |
|
|
|
Arteries |
Hypertension |
|
|
|
|
|
|
|
|
Blood |
|
|
Leukemia |
Aplastic anemia |
Heparin and warfarin therapy |
Hemophilia and other coagulation defects |
Thrombocytopenia |
|
|
| |
|
|
Polycythemia |
|
|
|
|
|
|
By far, the most common cause of epistaxis is trauma from nose picking. Many people are particularly vulnerable to this because of the closeness of Kiesselbach plexus of veins and capillaries to the surface of the septal mucosa. This cause can quickly be ruled out by nasoscopic examination of the anterior portion of the septum. This same area may be inflamed or ulcerated by various infections, particularly syphilis, tuberculosis, leprosy, and mucormycosis. Carcinomas in this area are uncommon, but the Schmincke tumor of the nasopharynx should not be forgotten; more important are allergic polyps, which usually do not bleed unless traumatized. Wegener midline granulomatosis is an autoimmune disease that may present with a bloody or nonbloody nasal discharge. It usually involves the sinuses, however, and must be differentiated from mucormycosis.
Other systemic diseases are prominent causes of epistaxis. Back pressure from obstructed veins in emphysema, asthma, and right heart failure must be considered. Arterial hypertension, from whatever etiology, is a common cause from middle-age onward. Rheumatic fever and blood dyscrasias round out the picture.
Other miscellaneous causes of epistaxis are skull fracture and menopause. In most cases, adequate examination of the nasal septum discloses the diagnosis and coagulation or nasal packing will suffice in treatment. The blood pressure should always be checked and, in recurrent cases, nasopharyngoscopy, coagulation studies, and a search for systemic disease must be made.
Other Useful Tests
- CBC (anemia, thrombocytopenia)
- Chemistry panel (liver disease, renal disease)
- Rumpel–Leede test (thrombocytopenia)
- Liver function test (cirrhosis)
- Prothrombin time (liver disease, vitamin K deficiency, drug effects)
- Partial thromboplastin time (DIC, hemophilia)
- X-rays of the sinuses (neoplasm)
- Nasopharyngoscopy (polyps, neoplasm)
- Circulation time (CHF)
- Arterial blood gas analysis (lung disease)
- Platelet count (thrombocytopenia)
- Bleeding time (thrombocytopenia, vascular purpura)
Book Source Details
- Book Title: Differential Diagnosis in Primary Care
- Author(s): R. Douglas Collins
- Year of Publication: 2007
- Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.
Other Book Chapters Related to Nosebleeds
Read excerpts from these other book chapters related to Nosebleeds:
Medical Books Excerpts
- EPISTAXIS
- "Algorithmic Diagnosis of Symptoms and Signs" (2003)
- [ read ]
- HEMOPTYSIS
- "Algorithmic Diagnosis of Symptoms and Signs" (2003)
- [ read ]
- EPISTAXIS
- "Differential Diagnosis in Primary Care" (2007)
- [ read ]
- Epistaxis
- "Handbook of Signs & Symptoms (Third Edition)" (2006)
- [ read ]
- Hemoptysis
- "Handbook of Signs & Symptoms (Third Edition)" (2006)
- [ read ]
- Epistaxis
- "Professional Guide to Diseases (Eighth Edition)" (2005)
- [ read ]
- Epistaxis
- "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
- [ read ]
- Hemoptysis
- "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
- [ read ]
- Hemoptysis
- "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
- [ read ]
- Nosebleed
- "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
- [ read ]
- Hemoptysis
- "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
- [ read ]
- Epistaxis
- "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
- [ read ]
- Hemoptysis
- "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
- [ read ]
- Epistaxis
- "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
- [ read ]
- Hemoptysis
- "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
- [ read ]
- Epistaxis
- "Nursing: Interpreting Signs and Symptoms" (2007)
- [ read ]
- EPISTAXIS
- "Differential Diagnosis in Primary Care" (2007)
- [ read ]
Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2008 Williams & Wilkins.
More About Causes of Nosebleeds
» Next page: HEMOPTYSIS (Differential Diagnosis in Primary Care)
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