- Tiredness, weight loss, fever, night sweats?
Why: may suggest malignancy such as leukemia which may also be associated with swollen and bleeding gums and also recurrent mouth infections.
- Gum ulceration?
Why: may suggest acute ulcerative gingivitis (Vincent's disease).
- Dry mouth (xerostomia)?
Why: may be due to diabetes, certain drugs , Sjogren's syndrome, dehydration, anemia, HIV infection or irradiation - can increase the risk of dental caries and thus gingivitis.
- Lip ulceration?
Why: would suggest herpes simplex labialis, syphilis and carcinoma.
- Tooth pain?
Why: may suggest tooth socket (alveolar) abscess.
- Symptoms of gingivitis?
Why: e.g. tender, red, swollen and bleeding gums - Gingivitis is an inflammatory process caused by failure to remove bacteria in the form of plaque from the tooth-gum junction.
- Symptoms of oral candidiasis?
Why: e.g. creamy white curd-like patches in the mouth which are removed only with difficulty and leave a bleeding surface. If the infection spreads to the esophagus it may cause pain with swallowing.
- Symptoms of glossitis (inflammation of the tongue)?
Why: e.g. smooth appearance of the tongue, tongue may be red. In later stages there may be shallow ulceration. May be due to nutritional deficiency in iron, folate or Vitamin B12.
- Symptoms of aphthous mouth ulcers (cancer sores)?
Why: e.g. lesions occurring on the inside of the lips or mouth which begin as a small painful vesicle which later breaks down to form the painful shallow ulcer. The ulcers heal without scarring. Cause is unknown, but may occur in Crohn's disease, Celiac disease or AIDS.
- Symptoms of Vincent's disease (acute ulcerative gingivitis)?
Why: e.g. tender, red, swollen, bleeding and ulcerated gums - occurs in the malnourished person with poor dentition and also in the immunocompromised person.
- Symptoms of hand, foot and mouth disease?
Why: e.g. fever, headache, sore mouth, shallow ulcers on the lining of the mouth, gums and tongue, blisters on hands, palms and soles.
- Symptoms of herpes simplex labialis (cold sores)?
Why: e.g. prodrome of tingling, itching or burning sensation on the lips which usually precede any visible skin changes by 24 hrs. Prodrome is followed by development of fluid filled vesicles which erode to become ulcers on the lips.
- Symptoms of angular stomatitis?
Why: e.g. cracks at the corners of the mouth. Possible causes may include Vitamin B6, B12, folate and iron deficiency.
- Symptoms of Behcet's syndrome?
Why: e.g. recurrent oral aphthous ulcers, recurrent genital aphthous ulcers, features of posterior uveitis (blurred vision and floaters), erythema nodosum (painful nodules on the arms and legs).
- Symptoms of erythema multiforme?
Why: e.g. acute eruption involving the skin and mouth mainly in children, adolescents and young adults. Lesions are raised patches of concentric rings (iris or target lesions). The mouth lesions are tender and painful. It may be associated with herpes simplex type 1, systemic lupus erythematosus, Hodgkin's disease, myeloma, tuberculosis and some medications.
- Symptoms of diabetes
Why: e.g. frequent urination, excessive thirst, weight loss, fatigue - can cause recurrent mouth infections, dry mouth and lips.
- Symptoms of menopause?
Why: Hormonal changes occurring during menopause may be associated with burning mouth.
- Symptoms of riboflavin (Vitamin B2) deficiency?
Why: e.g. fissuring at the corners of the mouth, red inflamed tongue, seborrheic dermatitis on face, scrotum or vagina.
- Symptoms of Primary Sjogren's syndrome?
Why: e.g. dry eyes, dryness of the mouth, skin or vagina. Dry mouth can predispose to recurrent mouth infections including oral candidiasis. This syndrome may be associated with many systemic conditions such as Raynaud's phenomenon, difficulty in swallowing (as seen in systemic sclerosis), painful joints (like that seen with systemic lupus erythematosus), thyroid disease, myasthenia gravis, primary biliary cirrhosis, chronic active hepatitis, renal diabetes insipidus, renal tubular acidosis and vasculitis.
- Symptoms of Chronic mucocutaneous candidiasis?
Why: a distinct syndrome usually occurring in children comprising of recurrent or persistent oral thrush, finger or toe bed infection and skin infection.
- Symptoms of temporomandibular joint dysfunction?
Why: e.g. pain felt over the jaw joint and localized to the region of the ear but may radiate forwards to the cheek and even the neck; pain and limitation of jaw movements especially on opening the mouth, clicking and crackling in the jaw joint with movement.
- Symptoms of Scrombotoxic fish poisoning?
Why: e.g. 2-3 hours after ingestion may experience flushing, burning of the mouth, itchiness, headache, hives, nausea, vomiting and difficulty with breathing.
- Symptoms of depression, anxiety and stress?
Why: the cause of most cases of burning and painful mouth is unknown. There is a high prevalence of anxiety, depression and reactions to stress suggesting a psychological basis but a causal link has not been clearly established.