Again, the female genital tract can be infected by all sizes of organisms, thus a useful method for recalling the causes of a purulent vaginal discharge is to work from the smallest to the largest organism. Thus, we begin with herpes progenitalis and proceed to gonorrhea and nonspecific bacterial infection (now known as Gardnerella vaginalis), trichomoniasis, and, finally, moniliasis. This, however, does not cover all the causes of a nonbloody vaginal discharge. Consequently, anatomy is applied as well.
VAGINAL DISCHARGE
At the vulva, one encounters vulvitis, bartholinitis, and vulval carcinoma. In the vagina, the conditions mentioned above are formed in addition to senile vaginitis, foreign bodies, and vaginal carcinomas. One should also not forget vesicovaginal, rectovaginal, and enteric fistulas. At the cervix, cervicitis and endocervicitis (gonorrheal or nonspecific), cervical polyps, and carcinomas need to be mentioned. In the uterus, endometritis, polyps, and carcinomas are recalled, but the latter two conditions are usually associated with a bloody discharge. Finally, salpingitis produces a mucopurulent discharge.
To workup a vaginal discharge, simply examining a fresh wet saline and KOH (10%) preparation will expose the most common offenders, namely Trichomonas and Candida. Some physicians treat all patients with negative findings on these examinations as a nonspecific bacterial vaginitis, but this is not a particularly scientific procedure. It is best to do a smear and culture (especially for gonococci). Cultures are also available for Trichomonas and Candida. If gonorrhea is suspected, material from the endocervix should be cultured. Chlamydia cultures are routinely done in some clinics.
Obviously, if the cervix is eroded and the discharge seems to be coming from there, biopsy and conization may be indicated. Referral to a gynecologist is preferred if this procedure is deemed necessary; however, the primary physician may prefer to cauterize the superficial lesions. Patients with discharges thought to be due to lesions beyond the cervix should probably be referred.
Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.
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Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2008 Williams & Wilkins.
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Title: Differential Diagnosis in Primary Care Authors: R. Douglas Collins Publisher: Lippincott Williams & Wilkins Copyright: 2007 ISBN: 0-7817-6812-8 
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