Conditions listing Tetralogy of Fallot as a symptom may also be potential underlying causes of Tetralogy of Fallot. Our database lists the following as having Tetralogy of Fallot as a symptom of that condition:
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Tetralogy of Fallot may be found in:
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The cause of tetralogy of Fallot is unknown, but it results from embryologic hypoplasia of the outflow tract of the right ventricle. Multiple factors, such as Down syndrome, have been associated with its presence. Prenatal risk factors include maternal rubella or other viral illnesses, poor prenatal nutrition, maternal alcoholism, mother older than age 40, and diabetes.
Tetralogy of Fallot occurs in approximately 5 of every 10,000 infants and accounts for about 10% of all congenital heart diseases. It occurs equally in boys and girls. Before surgical advances made correction possible, about one-third of these children died in infancy.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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