Diseases » Tick-borne diseases » Clinical Trials

Clinical Trials for Tick-borne diseases

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Tick-borne diseases is grouped into the following categories:-

View by trial name

View by drugs used in Tick-borne diseases clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Tick-borne diseases:

Lyme Disease Prevention Program - This study has been completed (Current: 23 Nov 2006)
Study and Treatment of Post Lyme Disease (STOP-LD) - This study has been completed (Current: 23 Nov 2006) - Antibiotics
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seronegative Chronic Lyme Disease - This study has been completed (Current: 23 Nov 2006) - ceftriaxone,doxycycline
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme Disease - This study has been completed (Current: 23 Nov 2006) - ceftriaxone,doxycycline
Evaluation of Lyme Disease: Clinical, Microbiological and Immunological Characteristics - This study is currently recruiting patients (Current: 23 Nov 2006)
Evaluation, Treatment, and Follow-up of Patients With Lyme Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
Brain Imaging and Retreatment Study of Persistent Lyme Disease - This study has been completed (Current: 23 Nov 2006) - ceftriaxone
Safety of and Immune Response to a Tick-Borne Encephalitis Vaccine (LGT(TP21)/DEN4) in Healthy Adults - This study is currently recruiting patients (Current: 23 Nov 2006)
Effect of Intravenous Ceftriaxone and Oral Doxycycline for Lyme Neuroborreliosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Ceftriaxone,Doxycycline
Safety and Immunogenicity Study of 3 Vaccinations With TICOVAC in 2 Dosages in Healthy Children Aged Between 6 Months and 3 Years - This study has been completed (Current: 23 Nov 2006)
Dose-Finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 1 to 6 Years. - This study has been completed (Current: 23 Nov 2006)
Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years - This study has been completed (Current: 23 Nov 2006)
Dose-Finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 6 to 16 Years. - This study has been completed (Current: 23 Nov 2006)
Safety Study in Volunteers From 16 to 65 Years of Age: FSME IMMUN NEW vs. ENCEPUR - This study has been completed (Current: 23 Nov 2006)
FSME IMMUN NEW Follow-Up to Study 199 in Children Aged 1 to 6 Years - This study has been completed (Current: 23 Nov 2006)
Safety Study of FSME-IMMUN NEW in Healthy Children and Adolescents Aged 1 to 15 Years - This study has been completed (Current: 23 Nov 2006)
FSME IMMUN NEW Follow-Up to Study 208 in Volunteers Aged 16 to 66 Years - This study has been completed (Current: 23 Nov 2006)
FSME IMMUN NEW Follow-Up to Study 205 in Children Aged 6 to 16 Years - This study has been completed (Current: 23 Nov 2006)
Immunogenicity and Safety Study of a Rapid Immunization Schedule With FSME-IMMUN 0.5 mL in Healthy Adults Aged 16 - 65 Years - This study has been completed (Current: 23 Nov 2006)
TBE Antibody Persistence and Booster Vaccination Study in Children and Adolescents (Follow-up to Study 209) - This study has been completed (Current: 23 Nov 2006)
Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225) - This study has been completed (Current: 23 Nov 2006)
Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children. - This study is no longer recruiting patients (Current: 23 Nov 2006)
Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Tick-borne diseases

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Tick-borne diseases: