Diagnosis of Toxic Shock Syndrome
Toxic Shock Syndrome Diagnosis: Book Excerpts
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Diagnostic Tests for Toxic Shock Syndrome: Online Medical Books
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Toxic shock syndrome:
Diagnosis
(Professional Guide to Diseases (Eighth Edition))
Diagnosis is based on several criteria: fever, hypotension, rash that peels after 1 to 2 weeks, and at least 3 organs with signs of dysfunction. In some cases, blood cultures may be positive for S. aureus. Organs with signs of dysfunction may include:
❑GI effects, including vomiting and profuse diarrhea
❑muscular effects, with severe myalgias or a fivefold or greater increase in creatine kinase levels
❑mucous membrane effects such as frank hyperemia
❑renal involvement with elevated blood urea nitrogen or creatinine levels (at least twice the normal levels)
❑liver involvement with elevated bilirubin, aspartate aminotransferase, or alanine aminotransferase levels (at least twice the normal levels)
❑blood involvement with signs of thrombocytopenia and a platelet count of less than 100,000/µl
❑central nervous system effects such as disorientation without focal signs.
Negative results on blood tests for Rocky Mountain spotted fever, leptospirosis, and measles help rule out these disorders.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Toxic shock syndrome:
Diagnosis
(Handbook of Diseases)
A diagnosis of TSS is based on clinical findings and the presence of at least three of the following:
❑ GI effects, including vomiting and profuse diarrhea
❑ muscular effects, with severe myalgias or a fivefold or greater increase in creatine kinase
❑ mucous membrane effects such as frank hyperemia
❑ renal involvement with elevated blood urea nitrogen or creatinine levels (at least twice the normal levels)
❑ liver involvement with elevated bilirubin, alanine aminotransferase, or aspartate aminotransferase levels (at least twice the normal levels)
❑ blood involvement with signs of thrombocytopenia and a platelet count < 100,000/µl
❑ central nervous system effects such as disorientation without focal signs.
In addition, isolation of S. aureus from vaginal discharge or lesions helps support the diagnosis. Negative results on blood tests for Rocky Mountain spotted fever, leptospirosis, and measles help rule out these disorders.
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» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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