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Cyclosporine



Descriptions of Cyclosporine

Cyclosporine: A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)
Source: Diseases Database

Cyclosporine : 11-residue cyclic peptide produced by certain fungi which has antifungal and T cell specific immunosuppressive properties.
Source: CRISP

Basic Information: Cyclosporine

Count: Cyclosporine is listed as a: treatment for 10 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 3 conditions.

Treatments: list of all treatments

List of Diseases with Cyclosporine as a Treatment

The following list of conditions have 'Cyclosporine' or similar listed as a treatment in our database:

A

  • Autoimmune Hepatitis ... cyclosporine

    B

  • Behcet's Disease ... Cyclosporine

    C

  • Childhood nephrotic syndrome ... cyclosporine

    E

  • Eczema ... cyclosporine

    I

  • Immune Thrombocytopenic Purpura ... cyclosporine

    M

  • Myasthenia Gravis ... cyclosporine

    P

  • Primary sclerosing cholangitis ... Cyclosporine
  • Psoriasis ... cyclosporine (Neoral®)

    R

  • Rheumatoid arthritis ... Cyclosporine (Sandimmune, Neoral)

    T

  • Transplants ... Cyclosporine

    List of Diseases with Cyclosporine as a Research Treatment

    The following list of conditions have 'Cyclosporine' or similar listed as a research treatment or other research area in our database:

    C

  • Crohn's disease ... cyclosporine

    S

  • Sarcoidosis ... Cyclosporine

    U

  • Ulcerative colitis ... Cyclosporine

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