Indomethacin: a nonsteroidal anti-inflammatory drug (trade name Indocin)
Source: WordNet 2.1
Indomethacin: A synthetic nonsteroidal indole derivative with anti-inflammatory activity and chemopreventive properties. As a nonsteroidal anti-inflammatory drug (NSAID), indomethacin inhibits the enzyme cyclooxygenase, thereby preventing cyclooxygenase-mediated DNA adduct formation by heterocyclic aromatic amines. This agent also may inhibit the expression of multidrug-resistant protein type 1, resulting in increased efficacies of some antineoplastic agents in treating multi-drug resistant tumors. In addition, indomethacin activates phosphatases that inhibit the migration and proliferation of cancer cells and downregulates survivin, which may result in tumor cell apoptosis. (NCI04)
Source: Diseases Database
Indomethacin : non-steroidal anti-inflammatory agent that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids; also inhibits the motility of polymorphonuclear leukocytes.
Source: CRISP
Count: Indomethacin is listed as a: treatment for 4 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 0 conditions.
Treatments: list of all treatments
The following list of conditions have 'Indomethacin' or similar listed as a treatment in our database:
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