Diagnosis of Uterine fibroids
Uterine fibroids Diagnosis: Book Excerpts
Diagnosis of Uterine fibroids: medical news summaries:
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Diagnostic Tests for Uterine fibroids: Online Medical Books
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Abnormal Uterine Bleeding:
Differential Diagnosis
(In a Page: Signs and Symptoms)
- Endometrial hyperplasia
–Endogenous estrogen excess (e.g., obesity,
tumor)
–Exogenous estrogen
–DUB is a diagnosis of exclusion (usually
not cyclic, occurs irregularly throughout the menstrual cycle)
-
Polycystic ovarian syndrome
-
Hypo- or hyperthyroidism
-
Endometrial atrophy
–Caused by long-term progestin or oral contraceptive use
-
Anatomic or structural lesions
–Uterine leiomyoma (fibroids)
–Foreign body (often intrauterine device)
–Cervical or uterine polyps
-
Pelvic infection (cervicitis, pelvic inflammatory disease)
-
Hypothalamic lesion
-
Hyperprolactinemia
-
Medications (e.g., exogenous estrogen, phenothiazines, reserpine)
-
Coagulation disorders
–Platelet dysfunction: Thrombocytopenia, leukemia, medications (e.g., aspirin, NSAIDs)
–Clotting factor abnormality: Von Willebrand's disease, hemophilia, hepatic or renal disease, anticoagulant use
-
Complications of pregnancy
–Spontaneous abortion (miscarriage)
–Ectopic pregnancy
–Placenta previa
–Placental abruption
-
Endometrial cancer
–Risk factors include older age, chronic anovulation, obesity, hypertension, DM, and unopposed estrogen
-
Systemic disease (e.g., HIV, hepatic disease, renal disease)
-
Nonuterine bleeding
–Vaginal (tear, trauma, or cancer)
–Cervical (trauma or cancer)
–Urinary (UTI or cancer)
–Rectal (bleeding, trauma, fissure, or cancer)
-
Other malignancy (ovarian or uterine tumor, sarcoma)
-
Endometrioma
Workup and Diagnosis
-
History, physical, pelvic, and rectal examinations
-
Pap smear
-
- Initial labs may include β-hCG (qualitative and, if positive, quantitative); CBC with differential; TSH, LH, FSH, estradiol, testosterone, prolactin, and DHEA-S levels
-
Consider PT/PTT, peripheral smear, clotting factor assays, liver function tests, serum progesterone, and BUN/creatinine to evaluate for coagulopathy, hepatic, or renal disease
-
Pelvic ultrasound may reveal adnexal or uterine masses or other pathology
-
Transvaginal ultrasound is more accurate than pelvic ultrasound in evaluating the endometrium
-
Endometrial biopsy and progesterone challenge test are helpful in the evaluation of estrogen excess
–Administration of medroxyprogesterone for 10 days results in withdrawal bleeding if adequate estrogen is present
-
CT scan may be helpful if malignancy is suspected
-
Hysteroscopy for evaluation of endometrium and uterine cavity
-
Diagnostic dilatation and curettage is more invasive but offers more information than endometrial biopsy
» READ BOOK EXCERPT ONLINE »
Source: In a Page: Signs and Symptoms, 2004
Uterine leiomyomas:
Diagnosis
(Professional Guide to Diseases (Eighth Edition))
Clinical findings and patient history may suggest uterine leiomyomas. Bimanual examination may reveal an enlarged, firm, nontender, and irregularly contoured uterus. Ultrasound (transvaginal or pelvic) or magnetic resonance imaging allows accurate assessment of the dimensions, number, and location of tumors. Other diagnostic procedures include hysterosalpingography, dilatation and curettage, endometrial biopsy, and laparoscopy.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Uterine leiomyomas:
Diagnosis
(Handbook of Diseases)
Clinical findings and the patient history suggest uterine leiomyomas.
❑ Blood studies showing anemia from abnormal bleeding support the diagnosis.
❑ Bimanual examination may reveal an enlarged, firm, nontender, and irregularly contoured uterus.
❑ Ultrasonography allows accurate assessment of the dimensions, number, and location of tumors. Magnetic resonance imaging is particularly useful for fibroid imaging.
❑ Other diagnostic procedures include hysterosalpingography, dilatation and curettage, endometrial biopsy, and laparoscopy.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
For many women, any gynecologic procedure is an unattractive prospect, and something with a name like "hysteroscopy" sounds downright frightening. In...
As many as 20 to 50 percent of all women develop fibroids. These benign muscle tumors usually grow in the uterus, and can cause pain, and in some...
As many as 20 to 50 percent of all women develop fibroids. These benign muscle tumors usually grow in the uterus, and can cause pain, and in some...
If you are suffering from abnormal bleeding, you may have submucus fibroid tumors. These tumors can cause severe cramping, fatigue, heavy menstrual...
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