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Diseases » Uterine fibroids » Diagnosis
 

Diagnosis of Uterine fibroids

Uterine fibroids Diagnosis: Book Excerpts

Diagnosis of Uterine fibroids: medical news summaries:

The following medical news items are relevant to diagnosis and misdiagnosis issues for Uterine fibroids:

Diagnostic Tests for Uterine fibroids: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about diagnostis of Uterine fibroids.


Abnormal Uterine Bleeding: Differential Diagnosis
(In a Page: Signs and Symptoms)

  • Endometrial hyperplasia
    –Endogenous estrogen excess (e.g., obesity, tumor)
    –Exogenous estrogen
    –DUB is a diagnosis of exclusion (usually not cyclic, occurs irregularly throughout the menstrual cycle)
  • Polycystic ovarian syndrome
  • Hypo- or hyperthyroidism
    • Endometrial atrophy
      –Caused by long-term progestin or oral contraceptive use
    • Anatomic or structural lesions
      –Uterine leiomyoma (fibroids)
      –Foreign body (often intrauterine device)
      –Cervical or uterine polyps
    • Pelvic infection (cervicitis, pelvic inflammatory disease)
    • Hypothalamic lesion
    • Hyperprolactinemia
    • Medications (e.g., exogenous estrogen, phenothiazines, reserpine)
    • Coagulation disorders
      –Platelet dysfunction: Thrombocytopenia, leukemia, medications (e.g., aspirin, NSAIDs)
      –Clotting factor abnormality: Von Willebrand's disease, hemophilia, hepatic or renal disease, anticoagulant use
      • Complications of pregnancy
        –Spontaneous abortion (miscarriage)
        –Ectopic pregnancy
        –Placenta previa
        –Placental abruption
        • Endometrial cancer
          –Risk factors include older age, chronic anovulation, obesity, hypertension, DM, and unopposed estrogen
        • Systemic disease (e.g., HIV, hepatic disease, renal disease)
        • Nonuterine bleeding
          –Vaginal (tear, trauma, or cancer)
          –Cervical (trauma or cancer)
          –Urinary (UTI or cancer)
          –Rectal (bleeding, trauma, fissure, or cancer)
        • Other malignancy (ovarian or uterine tumor, sarcoma)
        • Endometrioma

        Workup and Diagnosis

        • History, physical, pelvic, and rectal examinations
          • Pap smear
          • Initial labs may include β-hCG (qualitative and, if positive, quantitative); CBC with differential; TSH, LH, FSH, estradiol, testosterone, prolactin, and DHEA-S levels
        • Consider PT/PTT, peripheral smear, clotting factor assays, liver function tests, serum progesterone, and BUN/creatinine to evaluate for coagulopathy, hepatic, or renal disease
        • Pelvic ultrasound may reveal adnexal or uterine masses or other pathology
        • Transvaginal ultrasound is more accurate than pelvic ultrasound in evaluating the endometrium
        • Endometrial biopsy and progesterone challenge test are helpful in the evaluation of estrogen excess
          –Administration of medroxyprogesterone for 10 days results in withdrawal bleeding if adequate estrogen is present
      • CT scan may be helpful if malignancy is suspected
      • Hysteroscopy for evaluation of endometrium and uterine cavity
      • Diagnostic dilatation and curettage is more invasive but offers more information than endometrial biopsy

» READ BOOK EXCERPT ONLINE »

Source: In a Page: Signs and Symptoms, 2004

Uterine leiomyomas: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

Clinical findings and patient history may suggest uterine leiomyomas. Bimanual examination may reveal an enlarged, firm, nontender, and irregularly contoured uterus. Ultrasound (transvaginal or pelvic) or magnetic resonance imaging allows accurate assessment of the dimensions, number, and location of tumors. Other diagnostic procedures include hysterosalpingography, dilatation and curettage, endometrial biopsy, and laparoscopy.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Uterine leiomyomas: Diagnosis
(Handbook of Diseases)

Clinical findings and the patient history suggest uterine leiomyomas.

Blood studies showing anemia from abnormal bleeding support the diagnosis.

Bimanual examination may reveal an enlarged, firm, nontender, and irregularly contoured uterus.

Ultrasonography allows accurate assessment of the dimensions, number, and location of tumors. Magnetic resonance imaging is particularly useful for fibroid imaging.

❑ Other diagnostic procedures include hysterosalpingography, dilatation and curettage, endometrial biopsy, and laparoscopy.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003


 » Next page: Signs of Uterine fibroids

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