Symptoms of West Nile fever

List of symptoms of West Nile fever:

The list of signs and symptoms mentioned in various sources for West Nile fever includes the 22 symptoms listed below:

• Mild symptoms
• Fever
• Headache
• Body aches
• Skin rash
• Swollen lymph glands
• Fever
• Headache
• Neck pain
• Vomiting
• Muscle ache
• Maculopapular rash
• Diarrhea
• Photophobia
• Altered mental status
• Muscle weakness
• Malaise
• Myalgia
• Stiff neck
• Lethargy
• Coma
• Seizures

Note that West Nile fever symptoms usually refers to various symptoms known to a patient, but the phrase West Nile fever signs may refer to those signs only noticable by a doctor.

More ways to research these symptoms: To research other symptoms use the symptom center, or to research causes of more than one symptom in combination, try our multi-symptom search.

Research More About West Nile fever

Do I have West Nile fever?

• West Nile fever: Introduction
• West Nile fever: Diagnostic Testing to confirm diagnosis
• Home Diagnostic Testing
• Alternative diagnoses and misdiagnosis for West Nile fever
• Failure to Diagnose West Nile fever
• How serious is it?
• Treatments for West Nile fever
• More about West Nile fever

Home Diagnostic Testing

Home medical tests related to West Nile fever:

• Cold & Flu: Home Testing:
  • Home Fever Tests
  • Home Ear Infection Tests
  • Home Flu Tests

Wrongly Diagnosed with West Nile fever?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for West Nile fever includes:

• Guillain-Barre Syndrome

See the full list of 1 alternative diagnoses for West Nile fever

More about symptoms of West Nile fever:

More information about symptoms of West Nile fever and related conditions:

• Other diseases with similar symptoms and common misdiagnoses
• Tests to determine if these are the symptoms of West Nile fever
• Symptoms that may be caused by complications of West Nile fever
• Underlying causes of West Nile fever
• Associated conditions for West Nile fever
• Risk factors for West Nile fever

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

• Altered mental status - see all causes of Mental problems
• Body aches - see all causes of Aches
• Coma - see all causes of Coma
• Diarrhea - see all causes of Diarrhea
• Fever - see all causes of Fever
• Fever - see all causes of Fever
• Headache - see all causes of Headache
• Headache - see all causes of Headache
• Lethargy - see all causes of Lethargy
• Maculopapular rash - see all causes of Maculopapular rash
• Malaise - see all causes of Malaise
• Mild symptoms - see all causes of Vague symptoms
• Muscle ache - see all causes of Muscle aches
• Muscle weakness - see all causes of Muscle weakness
• Myalgia - see all causes of Myalgia
• Neck pain - see all causes of Neck pain
• Photophobia - see all causes of Photophobia
• Seizures - see all causes of Seizures
• Skin rash - see all causes of Rash
• Stiff neck - see all causes of Stiff neck
• Swollen lymph glands - see all causes of Swollen lymph glands
• Vomiting - see all causes of Vomiting

Medical Books Online about West Nile fever

Medical Books Excerpts Excerpts of published medical book chapters related to West Nile fever are available from published medical books for more detailed information about West Nile fever.

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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Symptoms of West Nile fever: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of West Nile fever.

West Nile encephalitis: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

Mild infections of the virus are more common and include fever, headache, and body aches, usually accompanied by a skin rash and swollen lymph glands. Severe infections can be manifested by headache, high fever, neck stiffness, stupor, disorientation, coma, tremors, occasional convulsions, paralysis and, rarely, death.

The incubation period for West Nile encephalitis is anywhere from 5 to 15 days after exposure. Most patients who are bitten by an infected mosquito won’t develop symptoms. It's estimated that only 1 in 300 people who are bitten by an infected mosquito will actually get sick.

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Colorado tick fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

After a 3- to 6-day incubation period, Colorado tick fever begins abruptly with chills; temperature of 104° F (40° C); severe aching of back, arms, and legs; lethargy; and headache with eye movement such as extraocular movement. Photophobia, abdominal pain, nausea, and vomiting may occur. Rare effects include petechial or maculopapular rashes and central nervous system involvement. Symptoms subside after several days but return within 2 to 3 days and continue for 3 more days before slowly disappearing. Complete recovery usually follows.

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Lassa fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

After a 7- to 18-day incubation period, this disease produces a fever that persists for 2 to 3 weeks, exudative pharyngitis, oral ulcers, lymphadenopathy with swelling of the face and neck, purpura, conjunctivitis, and bradycardia. Severe infection may also cause hepatitis, myocarditis, pleural infection, encephalitis, and permanent unilateral or bilateral deafness.

Virus multiplication in reticuloendothelial cells causes capillary lesions that lead to erythrocyte and platelet loss; mild to moderate thrombocytopenia (with a tendency toward bleeding); and secondary bacterial infection. These capillary lesions may also cause focal hemorrhage in the stomach, small intestine, kidneys, lungs, and brain and, possibly, hemorrhagic shock and peripheral vascular collapse.

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Relapsing fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

The incubation period for relapsing fever is 5 to 15 days (the average is 7 days). Clinically, tick- and louse-borne diseases are similar. Both begin suddenly, with a temperature approaching 105° F (40.6° C), prostration, headache, severe myalgia, arthralgia, diarrhea, vomiting, coughing, and eye or chest pains. Splenomegaly is common; hepatomegaly and lymphade-nopathy may occur. During febrile periods, the victim's pulse and respiratory rates rise, and a transient macular rash may develop over his torso.

The first attack usually lasts from 3 to 6 days; then the patient's temperature drops quickly and is accompanied by profuse sweating. A skin rash on the trunk lasting 1 to 2 days is common after the primary febrile episode. The rash may be petechiae, macular, or papular. About 5 to 10 days later, a second febrile, symptomatic period begins. In louse-borne infection, additional relapses are unusual; but, in tick-borne cases, a second or third relapse is common. As the afebrile intervals become longer, relapses become shorter and milder because of antibody accumulation. Relapses are possibly due to antigenic changes in the Borrelia organism.

Complications from relapsing fever include nephritis, bronchitis, pneumonia, endocarditis, seizures, cranial nerve lesions, paralysis, and coma. Death may occur from hyperpyrexia, massive bleeding, circulatory failure, splenic rupture, or a secondary infection.

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Rheumatic fever and rheumatic heart disease: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

In 95% of patients, rheumatic fever characteristically follows a streptococcal infection that appeared a few days to 6 weeks earlier. A temperature of at least 100.4° F (38° C) occurs, and most patients complain of migratory joint pain or polyarthritis. Swelling, redness, and signs of effusion usually accompany such pain, which most commonly affects the knees, ankles, elbows, or hips. In 5% of patients (generally those with carditis), rheumatic fever causes skin lesions such as erythema marginatum, a nonpruritic, macular, transient rash that gives rise to red lesions with blanched centers. Rheumatic fever may also produce firm, movable, nontender, subcutaneous nodules about 3 mm to 2 cm in diameter, usually near tendons or bony prominences of joints (especially the elbows, knuckles, wrists, and knees) and less often on the scalp and backs of the hands. These nodules persist for a few days to several weeks and, like erythema marginatum, often accompany carditis.

Later, rheumatic fever may cause transient chorea, which develops up to 6 months after the original streptococcal infection. Mild chorea may produce hyperirritability, a deterioration in handwriting, or an inability to concentrate. Severe chorea (Sydenham’s chorea) causes purposeless, nonrepetitive, involuntary muscle spasms; poor muscle coordination; and weakness. Chorea always resolves without residual neurologic damage.

The most destructive effect of rheumatic fever is carditis, which develops in up to 50% of patients and may affect the endocardium, myocardium, pericardium, or the heart valves. Pericarditis causes a pericardial friction rub and, occasionally, pain and effusion. Myocarditis produces characteristic lesions called Aschoff bodies (in the acute stages) and cellular swelling and fragmentation of interstitial collagen, leading to formation of a progressively fibrotic nodule and interstitial scars. Endocarditis causes valve leaflet swelling, erosion along the lines of leaflet closure, and blood, platelet, and fibrin deposits, which form beadlike vegetations. Endocarditis affects the mitral valve most often in females; the aortic, most often in males. In both females and males, endocarditis affects the tricuspid valves occasionally and the pulmonic only rarely.

Severe rheumatic carditis may cause heart failure with dyspnea; right upper quadrant pain; tachycardia; tachypnea; a hacking, nonproductive cough; edema; and significant mitral and aortic murmurs. The most common of such murmurs include:

❑ a systolic murmur of mitral insufficiency (high-pitched, blowing, holosystolic, loudest at apex, possibly radiating to the anterior axillary line)

❑ a midsystolic murmur due to stiffening and swelling of the mitral leaflet

❑ occasionally, a diastolic murmur of aortic insufficiency (low-pitched, rumbling, almost inaudible). Valvular disease may eventually result in chronic valvular stenosis and insufficiency, including mitral stenosis and insufficiency, and aortic insufficiency. In children, mitral insufficiency remains the major sequela of rheumatic heart disease.

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Rocky Mountain spotted fever: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

The incubation period is usually about 7 days, but it can range from 2 to 14 days. Generally, the shorter the incubation time, the more severe the infection. Signs and symptoms, which usually begin abruptly, include a persistent temperature of 102° to 104° F (38.9° to 40° C); a generalized, excruciating headache; nausea and vomiting; and aching in the bones, muscles, joints, and back. In addition, the tongue is covered with a thick white coating that gradually turns brown as the fever persists and rises.

Initially, the skin may simply appear flushed. Between days 2 and 5, eruptions begin around the wrists, ankles, or forehead; within 2 days, they cover the entire body, including the scalp, palms, and soles. The rash consists of erythematous macules 1 to 5 mm in diameter that blanch on pressure; if untreated, the rash may become petechial and maculopapular. By the third week, the skin peels off and may become gangrenous over the elbows, fingers, and toes.

The pulse is strong initially, but it gradually becomes rapid (possibly reaching 150 beats/minute) and thready.

Alert A rapid pulse rate and hypotension (systolic pressure less than 90 mm Hg) herald imminent death from complete vascular collapse.

Other signs and symptoms include a bronchial cough, a rapid respiratory rate (as high as 60 breaths/minute), anorexia, constipation, abdominal pain, hepatomegaly, splenomegaly, insomnia, restlessness and, in extreme cases, delirium. Urine output falls to half of the normal level or less, is dark in color, and contains albumin. Complications, although uncommon, include lobar pneumonia, otitis media, pa-rotitis, disseminated intravascular coagulation (DIC) and, possibly, renal failure. In rare cases, RMSF leads to death.

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West Nile encephalitis: Signs and symptoms
(Handbook of Diseases)

Mild WNV infections are more common than severe infections and include symptoms such as fever, headache, and body aches, often accompanied by swollen lymph glands and a skin rash. Severe infections present with symptoms such as headache, high fever, neck stiffness, stupor, disorientation, coma, tremors, occasional convulsions, paralysis and, rarely, death.

The incubation period for West Nile encephalitis is 5 to 15 days after exposure.

CLINICAL TIP: Researchers estimate that only 1 in 300 people who are bitten by a mosquito infected with WNV actually develops the disease.

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Rheumatic fever and rheumatic heart disease: Signs and symptoms
(Handbook of Diseases)

In 95% of patients, rheumatic fever characteristically follows a streptococcal infection that appeared a few days to 6 weeks earlier. A temperature of at least 100.4° F (38° C) occurs.

Joint pain

Most patients complain of migratory joint pain or polyarthritis. Swelling, redness, and signs of effusion usually accompany such pain, which most commonly affects the knees, ankles, elbows, or hips.

Skin lesions and nodules

In 5% of patients (generally those with carditis), rheumatic fever causes skin lesions, such as erythema marginatum. This nonpruritic, macular, transient rash gives rise to red lesions with blanched centers.

Rheumatic fever may also produce firm, movable, nontender, subcutaneous nodules ⅛" to ¾" (0.5 to 2 cm) in diameter, usually near tendons or bony prominences of joints (especially the elbows, knuckles, wrists, and knees) and less commonly on the scalp and backs of the hands. These nodules persist for a few days to several weeks and, like erythema marginatum, often accompany carditis.

Chorea

Later, rheumatic fever may cause transient chorea, which develops up to 6 months after the original streptococcal infection.

Mild chorea may produce hyperirritability, a deterioration in handwriting, or an inability to concentrate. Severe chorea causes purposeless, nonrepetitive, involuntary muscle spasms; poor muscle coordination; and weakness. Chorea always resolves without residual neurologic damage.

Carditis

The most destructive effect of rheumatic fever is carditis, which develops in up to 50% of patients. It may affect the endocardium, myocardium, pericardium, or the heart valves.

Pericarditis causes a pericardial friction rub and, occasionally, pain and effusion. Myocarditis produces characteristic lesions called Aschoff bodies (in the acute stages) and cellular swelling and fragmentation of interstitial collagen, leading to formation of a progressively fibrotic nodule and interstitial scars.

Endocarditis causes valve leaflet swelling, erosion along the lines of leaflet closure, and blood, platelet, and fibrin deposits, which form beadlike vegetations. Endocarditis usually affects the mitral valve in females and the aortic valve in males. In both sexes, endocarditis affects the tricuspid valves occasionally and the pulmonic valve only rarely.

Severe rheumatic carditis may cause heart failure with dyspnea, right-upper-quadrant pain, tachycardia, tachypnea, significant mitral and aortic murmurs, and a hacking, nonproductive cough.

The most common murmurs include:

❑ a systolic murmur of mitral insufficiency (high-pitched, blowing, holo-systolic, loudest at apex, possibly radiating to the anterior axillary line)

❑ a midsystolic murmur caused by stiffening and swelling of the mitral leaflet

❑ occasionally, a diastolic murmur of aortic insufficiency. Valvular disease may eventually result in chronic valvular stenosis and insufficiency, including mitral stenosis and insufficiency and aortic insufficiency. In children, mitral insufficiency remains the major after-effect of rheumatic heart disease.

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Article Excerpts About Symptoms of West Nile fever:

NIAID Research on West Nile and Related Viruses, NIAID Fact Sheet: NIAID (Excerpt)

Most human infections are mild, causing fever, headache and body aches, often accompanied by a skin rash and swollen lymph glands. If the virus crosses the blood-brain barrier, however, it can cause life-threatening encephalitis, an inflammation of the brain. (Source: excerpt from NIAID Research on West Nile and Related Viruses, NIAID Fact Sheet: NIAID)

West Nile Virus Questions and Answers: DVBID (Excerpt)

Most infections are mild, and symptoms include fever, headache, and body aches, occasionally with skin rash and swollen lymph glands. More severe infection may be marked by headache, high fever, neck stiffness, stupor, disorientation, coma, tremors, convulsions, muscle weakness, paralysis, and, rarely, death. (Source: excerpt from West Nile Virus Questions and Answers: DVBID)

West Nile fever as a Cause of Symptoms or Medical Conditions

When considering symptoms of West Nile fever, it is also important to consider West Nile fever as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that West Nile fever may cause:

• Arboviral encephalitis
• Arthropathy
• Meningoencephalitis
• Muscle weakness
• Rash

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

• Diagnostic Testing for a Diagnosis of West Nile fever
• Research Alternative Diagnoses for West Nile fever
• How serious is West Nile fever?
• More about West Nile fever
• Online Diagnosis
• Self Diagnosis Pitfalls
• Pitfalls of Online Diagnosis
• Symptoms of the Silent Killer Diseases
• Lesser known silent killer diseases
• Books on signs and symptoms

Full list of premium articles on symptoms and diagnosis

About signs and symptoms of West Nile fever:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of West Nile fever. This signs and symptoms information for West Nile fever has been gathered from various sources, may not be fully accurate, and may not be the full list of West Nile fever signs or West Nile fever symptoms. Furthermore, signs and symptoms of West Nile fever may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed West Nile fever symptoms.