Prevalence and Incidence of Wilson's Disease
Prevalance of Wilson's Disease:
approximately 1 per 30,000 people suffer from Wilson disease, Genetics Home Reference website ... see also overview of Wilson's Disease.
Prevalance Rate:
approx 1 in 30,000 or 0.00% or 9,066 people in USA [Source statistic for calcuation: "approximately 1 per 30,000 people suffer from Wilson disease, Genetics Home Reference website" -- see also general information about data sources]
Wilson's Disease: Rare Disease
Wilson's Disease is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Wilson's Disease, or a subtype of Wilson's Disease,
affects less than 200,000 people in the US population.
Wilson's Disease Prevalence: Book Excerpts
Prevalence/Incidence of Wilson's Disease: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Wilson's Disease.
Wilson's disease:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Wilson’s disease is inherited as an autosomal recessive trait only when both parents carry the abnormal gene. There is a 25% chance that carrier parents will transmit Wilson’s disease (and a 50% chance that they will transmit the carrier state) to each of their offspring. The disease usually occurs among eastern Europeans, Sicilians, and other southern Italians.
Wilson’s disease causes excessive intestinal absorption of copper and subsequent decreased excretion of copper in the stool. Copper accumulates first in the liver. As liver cells die, they release copper into the bloodstream, which carries it to other tissues. For example, in the kidneys, excretion of excessive amounts of unbound copper in urine (hypercupriuria) results from ceruloplasmin deficiency, a serum enzyme normally bound to copper. The deposit of copper in the tissue decreases serum copper (hypocupremia).
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Wilson Disease:
Wilson Disease - epidemiology
(The 5-Minute Pediatric Consult)
Children usually present with hepatic manifestations; adolescents and young adults may present with neurologic symptoms.
Wilson Disease - incidence
- Incidence is 15–25 per million.
- Worldwide carrier rate is 1:100.
Wilson Disease - prevalence
- Prevalence is 1:30,000.
- Most cases present between ages 5 and 35.
- Worldwide distribution
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Wilson's Disease usually refers to the estimated population
of people who are managing Wilson's Disease at any given time.
The term 'incidence' of Wilson's Disease refers to the annual diagnosis rate,
or the number of new cases of Wilson's Disease diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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