Symptoms of Wilson's Disease
Symptoms of Wilson's Disease
The list of signs and symptoms mentioned in various sources
for Wilson's Disease includes the 84
symptoms listed below:
Research symptoms & diagnosis of Wilson's Disease:
Wilson's Disease: Complications
Review medical complications possibly associated with Wilson's Disease:
Wilson's Disease Symptoms: Book Excerpts
Diagnostic Testing
Diagnostic testing of medical conditions related to Wilson's Disease:
Research More About Wilson's Disease
Do I have Wilson's Disease?
Wilson's Disease: Undiagnosed Conditions
Diseases that may be commonly undiagnosed in related medical areas:
Home Diagnostic Testing
Home medical tests related to Wilson's Disease:
- Bladder & Urinary Health: Home Testing:
- Liver Health & Hepatitis: Home Testing
- Kidney Health: Home Testing:
- Brain & Neurological Disorders: Related Home Testing:
- more home tests...»
Wrongly Diagnosed with Wilson's Disease?
The list of other diseases or medical conditions
that may be on the differential diagnosis list of alternative diagnoses
for Wilson's Disease includes:
See the full list of 13
alternative diagnoses for Wilson's Disease
Wilson's Disease: Research Doctors & Specialists
- Neurology (Brain/CNS Specialists):
- Stroke & Vascular Specialists:
- Urinary & Bladder Specialists (Urology):
- more specialists...»
Research all specialists including ratings, affiliations, and sanctions.
More about symptoms of Wilson's Disease:
More information about symptoms of Wilson's Disease and related conditions:
Other Possible Causes of these Symptoms
Click on any of the symptoms below to see a full list
of other causes including diseases, medical conditions, toxins, drug interactions,
or drug side effect causes of that symptom.
Medical Books Online about Wilson's Disease
Medical Books Excerpts
Excerpts of published medical book chapters related to Wilson's Disease
are available from published medical books
for more detailed information about Wilson's Disease.
Medical Books Excerpts
- Chorea
- "In a Page: Signs and Symptoms" (2004)
- [ read ]
- Chorea
- "In A Page: Pediatric Signs and Symptoms" (2007)
- [ read ]
- CHOREA
- "Differential Diagnosis in Primary Care" (2007)
- [ read ]
- Chorea
- "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
- [ read ]
- CHOREA
- "Differential Diagnosis in Primary Care" (2007)
- [ read ]
Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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Patient Surveys for Wilson's Disease
Symptoms of Wilson's Disease: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the symptoms of Wilson's Disease.
Wilson's disease:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Clinical manifestations of Wilson’s disease usually appear between ages 6 and 20, although signs and symptoms can occur as late as age 40. Symptoms result from damage to the body tissues caused by progressive copper deposition and vary according to the patient and the state of his disease. The characteristic symptom of Wilson’s disease is Kayser-Fleischer ring — a rusty brown ring of pigment at the periphery of the corneas. (See Kayser-Fleischer ring.) Fever may also occur in acute disease or with intercurrent infection. Other clinical features depend on the area affected.
❑ Liver (including spleen): hepatomegaly, splenomegaly, ascites, jaundice, hematemesis, spider angiomas, and thrombocytopenia, eventually leading to cirrhosis or subacute necrosis of the liver
❑ Blood: anemia and leukopenia
❑ Central nervous system: “wing-flapping” tremors in arms, pill-rolling tremors in hands, facial and muscular rigidity, dys-arthria, unsteady gait, and emotional and behavioral changes
❑ Genitourinary tract: aminoaciduria, proteinuria, uricosuria, glycosuria, and phosphaturia
❑ Musculoskeletal system (in severe disease): muscle wasting, contractures, deformities, osteomalacia, and pathologic fractures.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Wilson Disease:
Wilson Disease - signs & symptoms
(The 5-Minute Pediatric Consult)
- 45% of all patients present with liver disease, 35% with neurologic symptoms, 10% psychiatric
- Remaining 10%: Hemolytic anemia, jaundice, cardiomyopathy, other
- Consider WD in all cases of liver abnormality in which viral and autoimmune causes have been excluded.
- WD accounts for 8–10% of all chronic active hepatitis in children.
- Also consider WD in patient with unexplained neuropsychiatric symptoms.
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
Article Excerpts About Symptoms of Wilson's Disease:
Genes and Disease by the National Center for Biotechnology (Excerpt)
Liver disease is the most common symptom in children; neurological disease is most common in young adults. The cornea of the eye can also be affected: the 'Kayser-Fleischer ring' is a deep copper-colored ring at the periphery of the cornea, and is thought to represent copper deposits.
(Source: Genes and Disease by the National Center for Biotechnology)
Wilson's Disease: NIDDK (Excerpt)
The most
characteristic sign is the Kayser-Fleischer ring--a rusty brown ring
around the cornea of the eye that can be seen only through an eye exam.
Other signs depend on whether the damage occurs in the liver, blood,
central nervous system, urinary system, or musculoskeletal system. Many
signs would be detected only by a doctor, like swelling of the liver and
spleen; fluid buildup in the lining of the abdomen; anemia; low platelet
and white blood cell count in the blood; high levels of amino acids,
protein, uric acid, and carbohydrates in urine; and softening of the
bones. Some symptoms are more obvious, like jaundice, which appears as
yellowing of the eyes and skin; vomiting blood; speech and language
problems; tremors in the arms and hands; and rigid muscles.
(Source: excerpt from Wilson's Disease: NIDDK)
NINDS Wilson's Disease Information Page: NINDS (Excerpt)
The primary consequence for
approximately 40 percent of patients with Wilson's is liver disease. In
other patients the first symptoms are either neurological or psychiatric
or both, and include tremor, rigidity, drooling, difficulty with speech,
abrupt personality change, grossly inappropriate behavior and unexplicable
deterioration of school work, neurosis or psychosis.
(Source: excerpt from NINDS Wilson's Disease Information Page: NINDS)
Wilson's Disease as a Cause of Symptoms or Medical Conditions
When considering symptoms of Wilson's Disease, it is also important to consider Wilson's Disease as a possible cause of other medical conditions.
The Disease Database lists the following medical conditions that Wilson's Disease may cause:
- (Source - Diseases Database)
Wilson's Disease as a symptom:
For a more detailed analysis of Wilson's Disease as a symptom, including causes, drug side effect causes, and drug interaction causes, please see our Symptom Center information for Wilson's Disease.
Wilson's Disease: Onset and Incubation
Onset of Wilson's Disease: The onset of liver disease is usually at the age of 8-16 years.
Medical articles and books on symptoms:
These general reference articles may be of interest
in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
About signs and symptoms of Wilson's Disease:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Wilson's Disease.
This signs and symptoms information for Wilson's Disease has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Wilson's Disease signs or Wilson's Disease symptoms.
Furthermore, signs and symptoms of Wilson's Disease may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Wilson's Disease symptoms.
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» Next page: Diagnostic Tests for Wilson's Disease
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