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Diseases » Wilson's Disease » Treatments
 

Treatments for Wilson's Disease

Treatments for Wilson's Disease

The list of treatments mentioned in various sources for Wilson's Disease includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

Wilson's Disease: Is the Diagnosis Correct?

The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Wilson's Disease may include:

Hidden causes of Wilson's Disease may be incorrectly diagnosed:

  • Wilson disease is an autosomal recessive inherited condition caused by mutations or deletions of the ATP7B protein encoded by chromosome subbands 13q14.3-q 21.1
  • more causes...»

Wilson's Disease: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Wilson's Disease:

Wilson's Disease: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

Drugs and Medications used to treat Wilson's Disease:

Note:You must always seek professional medical advice about any prescription drug, OTC drug, medication, treatment or change in treatment plans.

Some of the different medications used in the treatment of Wilson's Disease include:

Hospitals & Medical Clinics: Wilson's Disease

Research quality ratings and patient incidents/safety measures for hospitals and medical facilities in specialties related to Wilson's Disease:

Hospital & Clinic quality ratings » »

Choosing the Best Treatment Hospital: More general information, not necessarily in relation to Wilson's Disease, on hospital and medical facility performance and surgical care quality:

Medical news summaries about treatments for Wilson's Disease:

The following medical news items are relevant to treatment of Wilson's Disease:

Discussion of treatments for Wilson's Disease:

Wilson's Disease: NIDDK (Excerpt)

The disease is treated with lifelong use of D-penicillamine or trientine hydrochloride, drugs that help remove copper from tissue. Patients will also need to take vitamin B6 and follow a low-copper diet, which means avoiding mushrooms, nuts, chocolate, dried fruit, liver, and shellfish. Taking extra zinc may be helpful in blocking the intestines' absorption of copper. (Source: excerpt from Wilson's Disease: NIDDK)

NINDS Wilson's Disease Information Page: NINDS (Excerpt)

Treatment of Wilson's disease generally consists of anti-copper agents to remove excess copper from the body and to prevent it from reaccumulating. Most cases are treated with the drugs zinc acetate, trientine, or penicillamine. Penicillamine and trientine increase urinary excretion of copper, however, both drugs can cause serious side effects. Zinc acetate — which blocks the absorption of copper, increases copper excretion in the stool, and causes no serious side affects — is often considered the treatment of choice. Tetrathiomolybdate, an experimental drug, also shows promise in treating Wilson's disease. In rare cases in which there is severe liver disease, a liver transplant may be needed. (Source: excerpt from NINDS Wilson's Disease Information Page: NINDS)

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Book Excerpts: Treatment of Wilson's Disease

Treatments of Wilson's Disease: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the treatments of Wilson's Disease.

Chorea: Treatment
(In a Page: Signs and Symptoms)

  • Huntington's disease: Antidepressants may reduce depressive symptoms; neuroleptics (e.g., haloperidol, clozapine) may suppress choreic movements; disease is progressive and fatal; genetic counseling is suggested
  • Sydenham's chorea is usually self-limited with symptom resolution within 15 weeks
  • Acute rheumatic fever: Corticosteroids may shorten course of chorea; antibiotic therapy with penicillin for at least 10 days
  • Drug-induced chorea: Discontinue or reduce dosage of implicated medications; atypical neuroleptics are associated with decreased risk of involuntary movements
  • Chorea gravidarum may require delivery
  • Wilson's disease: Copper-chelating agents
  • Neuroacanthocytosis: Usually fatal within 9 years of symptom onset
  • Specific therapy for lupus, hyperthyroidism, AIDS

» READ BOOK EXCERPT ONLINE »

Source: In a Page: Signs and Symptoms, 2004

Chorea: Treatment
(In A Page: Pediatric Signs and Symptoms)

    • Treatment should be reserved for patients in whom chorea severity interferes with function
      –Simple measures such as rest and avoidance of stress often alleviate symptoms
      –Anti-epilepsy medications are used for paroxysmal choreas
      –Dopamine blockers such as haloperidol and pimozide are used to decrease the movement disorder
    • Sydenham chorea
      –May be treated with valproate or pimozide
      –Immunosuppression with steroids, intravenous immunoglobulin or plasmapheresis have been used
      –Secondary prophylaxis with penicillin is required
  • Wilson disease: Treat with penicillamine, trientene chelation, or zinc
  • In cases of toxin-induced chorea, removal of the offending agent is usually sufficient

» READ BOOK EXCERPT ONLINE »

Source: In A Page: Pediatric Signs and Symptoms, 2007

Wilson's disease: Treatment
(Professional Guide to Diseases (Eighth Edition))

Treatment aims to reduce the amount of copper in the tissues, prevent additional accumulation, and manage hepatic disease. The most effective treatment for Wilson’s disease consists of lifetime therapy with pyridoxine (vitamin B6) in conjunction with penicillamine, a copper-chelating agent that mobilizes copper from the tissues and promotes its excretion in urine. The patient may require treatment with corticosteroids, such as prednisone, if he can’t tolerate penicillamine. Treatment also includes potassium and sodium supplements before meals to prevent GI absorption of copper. Exercises or physical therapy may be needed, and protective measures for the patient who’s confused or unable to care for himself. In some cases, a liver transplant may be the treatment of choice.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Chorea: Patient counseling
(Signs & Symptoms: A 2-in-1 Reference for Nurses)

Teach the patient and his family safety measures to reduce the risk of falls and poisoning. Discuss genetic counseling if Huntington’s disease is the cause of the patient’s chorea because each child of a parent with the disease has a 50% chance of inheriting it.

» READ BOOK EXCERPT ONLINE »

Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

Wilson Disease: Wilson Disease - TREATMENT
(The 5-Minute Pediatric Consult)

Early diagnosis is essential to limiting morbidity and mortality.

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008



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