Wiskott-Aldrich Syndrome

Introduction: Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome: An inherited immune system disorder that affects only males and is characterized by recurring infections, eczema and reduced level of blood platelets (thrombocytopenia). More detailed information about the symptoms, causes, and treatments of Wiskott-Aldrich Syndrome is available below.

Symptoms of Wiskott-Aldrich Syndrome

• Severe recurrent infections
• Bleeding easily
• Defective blood platelets
• Scaling skin rash (eczema)
• Itching

See full list of 40 symptoms of Wiskott-Aldrich Syndrome

Medical Textbooks Online about Wiskott-Aldrich Syndrome

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Causes of Wiskott-Aldrich Syndrome

Read more about causes of Wiskott-Aldrich Syndrome.

Treatments for Wiskott-Aldrich Syndrome

• Bone marrow transplantation
• Spleen removal
• Antibiotics
• IVIG
• Avoid allergic foods

Read more about treatments for Wiskott-Aldrich Syndrome

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Prognosis for Wiskott-Aldrich Syndrome

Prognosis for Wiskott-Aldrich Syndrome: bone marrow transplant improves prognosis

More about prognosis of Wiskott-Aldrich Syndrome

Reseach about Wiskott-Aldrich Syndrome

Visit our research pages for current research about Wiskott-Aldrich Syndrome treatments.

Clinical Trials for Wiskott-Aldrich Syndrome

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Wiskott-Aldrich Syndrome include:

• Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies - This study is no longer recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,busulfan,cyclophosphamide,cyclosporine,etoposide,methotrexate,methylprednisolone,prednisone
• Pilot Study of Allogeneic Bone Marrow Transplantation Plus Cyclosporine and Mycophenolate Mofetil to Induce Mixed Hematopoietic Chimerism in Patients With Primary T-Cell Immunodeficiency Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - cyclosporine,mycophenolate mofetil
• Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Pediatric Patients With Wiskott-Aldrich Syndrome: A Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases. - This study is currently recruiting patients (Current: 23 Nov 2006) - Intravenous immunoglobulin

See full list of 8 Clinical Trials for Wiskott-Aldrich Syndrome

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Definitions of Wiskott-Aldrich Syndrome:

Rare x-linked immunodeficiency syndrome of young boys characterized by eczema, thrombocytopenic purpura and recurrent pyogenic infection; IGM levels are low and IGA and IGE levels are elevated; lymphoreticular malignancies are common. - (Source - Diseases Database)

Wiskott-Aldrich Syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Wiskott-Aldrich Syndrome, or a subtype of Wiskott-Aldrich Syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)