The information below shows a list of types of X Chromosome Disorders, with information as to the annual incidence of each of these types of X Chromosome Disorders. Estimates of the people affected each year are calculated based on the available statistics.
Disease | Incidence Estimate | US people estimate | Statistic Used for Calculation |
| $Chromosome disorders affecting all or most of the X chromosome:$ | N/A | N/A | No information |
| Jacobs syndrome | N/A | N/A | No information |
| Klinefelter syndrome | approx 1 in 68,000 or 0.00% or 4,000 people in USA | 4,000 | 1-in-500 to 1-in-1000 male births (NIDCD) |
| Triple-X syndrome | approx 1 in 54,400,000 or 0.00% or 5 people in USA | 5 | 5-10 girls are born with triple X syndrome each day, Genetics Home Reference website |
| Turner Syndrome | N/A | N/A | No information |
| Intersex conditions | N/A | N/A | No information |
| $Genetic disorders affecting a single gene on the X chromosome:$ | N/A | N/A | No information |
| X-linked Recessive Genetic Diseases | N/A | N/A | No information |
| X-linked Dominant Genetic Diseases | N/A | N/A | No information |
| Fragile-X Syndrome | approx 1 in 3,000 or 0.03% or 90,666 people in USA | 90,666 | about 1 in 1500 males1. |
| X-Linked Agammaglobulinemia | N/A | N/A | No information |
For more information about types of X Chromosome Disorders, refer to our section on types of X Chromosome Disorders.
The medical term 'incidence' of X Chromosome Disorders usually refers to the annual diagnosis rate of new cases of X Chromosome Disorders. Prevalence is a different medical disease measure that refers to the estimated population of people who are managing X Chromosome Disorders at any given time (e.g. prevalence includes people who have had a medical condition for a long time). For more information on prevalence and incidence statistics, see about prevalence and incidence statistics.
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