Zollinger-Ellison syndrome

Zollinger-Ellison syndrome: Introduction

Zollinger-Ellison syndrome: Zollinger-Ellison syndrome is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum. The ... more about Zollinger-Ellison syndrome.

Zollinger-Ellison syndrome: A rare disorder where excessive levels of the hormone gastrin are released into the stomach which increases stomach acidity which results in peptic ulcer development. A hormone secreting pancreatic or duodenal tumor is usually the cause. More detailed information about the symptoms, causes, and treatments of Zollinger-Ellison syndrome is available below.

Symptoms of Zollinger-Ellison syndrome

• Stomach ulcer symptoms
• Peptic ulcers - see symptoms of peptic ulcers
• Abdominal pain
• Diarrhea
• Nausea
• more symptoms...»

See full list of 37 symptoms of Zollinger-Ellison syndrome

Home Diagnostic Testing

Home medical testing related to Zollinger-Ellison syndrome:

• Colon & Rectal Cancer: Home Testing
  • Home Colorectal Cancer Tests
  • Home Fecal Occult Bleeding Tests
• Food Allergies & Intolerances: Home Testing:
  • Home Food Allergy Tests
  • Home Food Intolerance Testing
  • Home Water Testing
  • Home Lead Poisoning Tests
  • Home Heavy Metal Poisoning Tests
• Cancer-Related Home Testing:
  • Home Prostate Testing
  • Home Prostate PSA Antigen Tests
  • Home Colorectal Cancer Testing
  • Home Fecal Occult Bleeding Testing
  • Home Breast Cancer Testing
  • Home Breast Lump Detection Kits
• Digestive-Related Home Testing:
  • Home Stomach Ulcer Tests
  • Home Colorectal Cancer Test Kits
  • Home Fecal Occult Bleeding Test Kits
• more tests...»

Zollinger-Ellison syndrome: Complications

Review possible medical complications related to Zollinger-Ellison syndrome:

• Pancreas tumors
• Gastrinomas
• Duodenal tumors
• Stomach ulcers
• Duodenal ulcers
• more complications...»

Medical Textbooks Online about Zollinger-Ellison syndrome

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Diagnostic Tests for Zollinger-Ellison syndrome

• Blood gastrin levels
• Stomach x-rays
• Endoscopy
• more tests...»

Read more about tests for Zollinger-Ellison syndrome

Wrongly Diagnosed with Zollinger-Ellison syndrome?

• Misdiagnosis of Zollinger-Ellison syndrome
• Failure to diagnose Zollinger-Ellison syndrome
• Hidden causes of Zollinger-Ellison syndrome (possibly wrongly diagnosed)
• Undiagnosed: Zollinger-Ellison syndrome

Zollinger-Ellison syndrome: Medical Mistakes

• Cancer Health Mistakes:
  • Cancer (All) -- Health Mistakes
  • Breast Cancer -- Health Mistakes
  • Colorectal Cancer -- Health Mistakes
• more mistakes...»

Zollinger-Ellison syndrome: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Zollinger-Ellison syndrome:

• Digestive Health
• Cancer
• more product offers...»

Zollinger-Ellison syndrome: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

• Chronic Digestive Disorders that can remain Undiagnosed:
  • Crohn's Disease -- Undiagnosed
  • Ulcerative Colitis -- Undiagnosed
  • Celiac Disease -- Undiagnosed
  • Heartburn -- Undiagnosed
  • GERD -- Undiagnosed
  • Inflammatory Bowel Disease -- Undiagnosed
  • Irritable Bowel Syndrome -- Undiagnosed
  • Carcinoid Syndrome -- Undiagnosed
  • Pancreatitis -- Undiagnosed
• more undiagnosed conditions...»

Misdiagnosis and Zollinger-Ellison syndrome

Chronic digestive conditions often misdiagnosed: When diagnosing chronic symptoms of the digestive tract, there are a variety of conditions that may be...read more »

Intestinal bacteria disorder may be hidden cause: One of the lesser known causes of diarrhea is an imbalance of bacterial in the gut, sometimes called intestinal imbalance. The digestive system contains a variety of ...read more »

Antibiotics often causes diarrhea: The use of antibiotics are very likely to cause some level of diarrhea in patients. The reason is that antibiotics kill off not only "bad" bacteria, but can also kill the "good" bacteria in...read more »

Food poisoning may actually be an infectious disease: Many people who come down with "stomach symptoms" like diarrhea assume that it's "something I ate" (i.e. ...read more »

Mesenteric adenitis misdiagnosed as appendicitis in children: Because appendicitis is one of the more feared conditions for a child with abdominal pain, it can be over...read more »

Spitz nevi misdiagnosed as dangerous melanoma skin cancer: One possible misdiagnosis to consider in lieu of melanoma is spitz nevi. See melanoma and spitz nevi....read more »

Celiac disease often fails to be diagnosed cause of chronic digestive symptoms: One of the most common chronic digestive conditions is celiac disease, a malabsorption disorder with a variety of symptoms (see symptoms of celiac...read more »

Chronic digestive diseases hard to diagnose: There is an inherent difficulty in diagnosing the various types of chronic digestive diseases. Some of the better known possibilities are ...read more »

Read more about Misdiagnosis and Zollinger-Ellison syndrome

Zollinger-Ellison syndrome: Research Doctors & Specialists

Research related physicians and medical specialists:

• Cancer Specialists:
  • Oncology (Cancer specialists)
  • Radiation Oncology
  • Pediatric Hematology / Oncology (Child Cancer/Leukemia)
  • Radiation Oncology (Diagnostic/X-rays)
  • Gynecological Oncology
  • Hematology (Blood/Leukemia Specialists)
  • Colon & Rectal Surgery
• Digestive Health Specialists (Gastroenterology):
  • Gastroenterology (Digestive Specialists)
  • Pediatric Gastroenterology (Child Digestive Health)
• more specialists...»

Other doctor, physician and specialist research services:

• Rate Your Doctor Online
• Research Your Doctor Online
• Review Patient Surveys About Your Doctor
• Research local specialists including ratings, affiliations, and sanctions.

Hospitals & Clinics: Zollinger-Ellison syndrome

Research quality ratings and patient safety measures for medical facilities in specialties related to Zollinger-Ellison syndrome:

• Cancer (Oncology) -- Hospital Quality Ratings
• Digestive Health (Gastroenterology) -- Hospital Quality Ratings
• more hospital ratings...»

Hospital & Clinic quality ratings » »

Choosing the Best Hospital: More general information, not necessarily in relation to Zollinger-Ellison syndrome, on hospital performance and surgical care quality:

• 50 Best Hospitals Report
• Outstanding Patient Experinece Award Winning Hospitals
• Women's Health Best Hospitals
• Patient Safety
• Hospital Quality and Clinical Excellence Study (2009)

Zollinger-Ellison syndrome: Rare Types

Rare types of diseases and disorders in related medical categories:

• Chronic Digestive Disorders -- Rare Types:
  • Crohn's Disease -- Rare Types
  • Ulcerative Colitis -- Rare Types
  • Celiac Disease -- Rare Types
  • Inflammatory Bowel Disease -- Rare Types
  • Irritable Bowel Syndrome -- Rare Types
  • Carcinoid Syndrome -- Rare Types
  • Pancreatitis -- Rare Types
  • Gallstones -- Rare Types
  • Lactose Intolerance -- Rare Types
• more rare diseases...»

Causes of Zollinger-Ellison syndrome

Read more about causes of Zollinger-Ellison syndrome.

More information about causes of Zollinger-Ellison syndrome:

• Zollinger-Ellison syndrome as a complication caused by other conditions
• Zollinger-Ellison syndrome as a symptom

Treatments for Zollinger-Ellison syndrome

• Medications used to reduce stomach acid - see also treatment of peptic ulcers
  • Cimetidine
  • Ranitidine
  • Famotidine
  • Omeprazole
• more treatments...»

See full list of 8 treatments for Zollinger-Ellison syndrome

News Archives for Zollinger-Ellison syndrome

Medical news articles related to Zollinger-Ellison syndrome include:

• More Assisted Reproduction, But Fewer Multiple Births
• Team Designs Gold Nanoparticles to Deliver Multiple Drugs
• Multiple Doses of Steroids Don't Help Preemies
• Multiple ICD Replacements Can Predict Complications
• Taking Multiple Pain Relievers May Cause Complications
• Surgery Better Than Stents for Multiple Blockages
• Partial Face Transplant Patient Doing Well
• more health news...»

Source: HealthDay News

Evidence Based Medicine Research for Zollinger-Ellison syndrome

Medical research articles related to Zollinger-Ellison syndrome include:

• What is the preferred proton pump inhibitor for treatment of reflux in a breast-feeding mother?
• How should continuous infusions of proton pump inhibitors be given for acute upper gastrointestinal bleeding?
• Pantoprazole
• Clostridium difficile infection ? are acid suppressant medicines a risk factor?
• Omeprazole
• In patients with gastro-oesophageal reflux treated with long term proton pump inhibitors is there any evidence of increased malignancy?
• Proton pump inhibitor
• Ranitidine hydrochloride
• more research...»

Click here to find more evidence-based articles on the TRIP Database

Videos for Zollinger-Ellison syndrome

Patient Surveys for Zollinger-Ellison syndrome

• Patient Profile Survey
  Take Survey  View Results
• Survey about the symptoms of your Zollinger-Ellison syndrome
  Take Survey  View Results

Reseach about Zollinger-Ellison syndrome

Visit our research pages for current research about Zollinger-Ellison syndrome treatments.

Clinical Trials for Zollinger-Ellison syndrome

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Zollinger-Ellison syndrome include:

• The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid - This study is currently recruiting patients (Current: 23 Nov 2006) - Pantoprazole,Omeprazole
• Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - Interferon
• Evaluating Patients With Abnormal Levels of Gastric Acid - This study has been completed (Current: 23 Nov 2006)
• Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome - This study has been completed (Current: 23 Nov 2006) - Esomeprazole magnesium
• Treatment of Zollinger-Ellison Syndrome With Prevacid - This study is currently recruiting patients (Current: 23 Nov 2006) - Lansoprazole (Prevacid)
• more trials...»

See full list of 8 Clinical Trials for Zollinger-Ellison syndrome

Statistics for Zollinger-Ellison syndrome

• Medical statistics for Zollinger-Ellison syndrome
• Prevalence and incidence statistics for Zollinger-Ellison syndrome
• Death and Mortality statistics for Zollinger-Ellison syndrome
• Society statistics for Zollinger-Ellison syndrome

Zollinger-Ellison syndrome: Broader Related Topics

• Cancer
• Pancreas conditions
• Stomach Conditions
• more types...»

Types of Zollinger-Ellison syndrome

Stories from Users Related to Zollinger-Ellison syndrome

• 10 yr son has multiple gi symptoms
• Multiple Symptoms, Just No Answers...
• Multiple symptoms started at same time- ready to give up! HELP PLEASE!
• Help Me Please, multiple symptoms worsening, life in jeopardy
• Four years of multiple symptoms
• Odd, Multiple Symptoms - Can you help?
• Multiple conditions - can't get diagnosis
• Daughter died after multiple misdiagnosis
• multiple symptoms, multiple specialists but no-one looking at the big picture
• multiple symptoms no insurance
• Multiple symptoms - doctors helpless
• Multiple symptoms, no real answers
• Multiple viruses at once?? Please help! Stumped!
• Multiple Symptoms with no diagnosis.. doctor is at a loss....
• multiple symptoms and no help..suggestions please.
• Multiple disability symptoms-doctor does not know
• Wrong Diagnosis? (Multiple Symptoms)
• Multiple symptoms, my mom's a doctor, she has no idea what's wrong with me
• multiple symptoms
• multiple symptoms - need help please

Related forums and medical stories:

• Digestive Conditions (139)
  • Help I cant eat!! Im scared..
  • Upper left abdominal pain after eating
  • Bloating/Distention/Intenstinal Gas
  • Pain below ribs (centre and right), upper and lower back
  • Diarrhea after eating
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about Zollinger-Ellison syndrome, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum. The pancreas is a gland located behind the stomach. It produces enzymes that break down fat, protein, and carbohydrates from food, and hormones like insulin that break down sugar. The duodenum is the top part of the small intestine.

The tumors are cancerous in 50 percent of cases. They secrete a substance called gastrin that causes the stomach to produce too much acid, which in turn causes the stomach and duodenal ulcers (peptic ulcers). The ulcers caused by Zollinger-Ellison syndrome are more painful and less responsive to treatment than ordinary peptic ulcers. (Source: excerpt from Zollinger-Ellison Syndrome: NIDDK)

Definitions of Zollinger-Ellison syndrome:

A gastrin-secreting tumor of the non-beta islet cells. It is usually located in the pancreas but is also found at other sites, as in the antrum of the stomach, hilus of the spleen, and regional lymph nodes. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1 (MEN-1). Gastrinomas in patients with MEN-1 are usually diffuse in nature. - (Source - Diseases Database)

Syndrome consisting of intractable peptic ulceration with gastric hypersecretion and hyperacidity - (Source - WordNet 2.1)

Zollinger-Ellison syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Zollinger-Ellison syndrome, or a subtype of Zollinger-Ellison syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Zollinger-Ellison syndrome as a "rare disease".
Source - Orphanet