Clinical Trials for Zollinger-Ellison syndrome

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Zollinger-Ellison syndrome is grouped into the following categories:-

• View by trial name
• View by drugs used in Zollinger-Ellison syndrome clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Zollinger-Ellison syndrome:

• The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid - This study is currently recruiting patients (Current: 23 Nov 2006) - Pantoprazole,Omeprazole
• Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - Interferon
• Evaluating Patients With Abnormal Levels of Gastric Acid - This study has been completed (Current: 23 Nov 2006)
• Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome - This study has been completed (Current: 23 Nov 2006) - Esomeprazole magnesium
• Treatment of Zollinger-Ellison Syndrome With Prevacid - This study is currently recruiting patients (Current: 23 Nov 2006) - Lansoprazole (Prevacid)
• Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas - This study has been completed (Current: 23 Nov 2006)
• Treatment of Zollinger-Ellison Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Zollinger-Ellison syndrome

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Zollinger-Ellison syndrome:

• Esomeprazole magnesium - Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome - This study has been completed (Current: 23 Nov 2006)
• Interferon - Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lansoprazole (Prevacid) - Treatment of Zollinger-Ellison Syndrome With Prevacid - This study is currently recruiting patients (Current: 23 Nov 2006)
• Omeprazole - The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pantoprazole - The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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